Basic Description

Synonyms	3-HYDROXYPICOLINIC ACID \| 874-24-8 \| 3-Hydroxypyridine-2-carboxylic acid \| 3-Hydroxy-2-pyridinecarboxylic acid \| 3-Hydroxypicolinicacid \| 3-HPA \| 2-Pyridinecarboxylic acid, 3-hydroxy- \| Pyridinecarboxylic acid, hydroxy- \| MFCD00006294 \| CHEBI:64342 \| 116357-04-1 \| XV7XP64JR5 \| C
Specifications & Purity	10mM in DMSO
Storage Temp	Store at -80°C
Shipped In	Ice chest + Ice pads

Associated Targets(Human)

DDO Tchem D-aspartate oxidase (0 Activities)

Discover Target: DDO

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MMP1 Tchem Interstitial collagenase (0 Activities)

Discover Target: MMP1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MMP9 Tchem Matrix metalloproteinase-9 (0 Activities)

Discover Target: MMP9

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ALOX5 Tclin Arachidonate 5-lipoxygenase (0 Activities)

Discover Target: ALOX5

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MMP2 Tchem 72 kDa type IV collagenase (0 Activities)

Discover Target: MMP2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

DAO Tchem D-amino-acid oxidase (0 Activities)

Discover Target: DAO

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NOS2 Tchem Nitric oxide synthase, inducible (0 Activities)

Discover Target: NOS2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MMP3 Tchem Stromelysin-1 (0 Activities)

Discover Target: MMP3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MMP8 Tchem Neutrophil collagenase (0 Activities)

Discover Target: MMP8

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ALOX5 Tclin Arachidonate 5-lipoxygenase (6568 Activities)

Discover Target: ALOX5

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TYR Tclin Tyrosinase (717 Activities)

Discover Target: TYR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MMP3 Tchem Matrix metalloproteinase 3 (3433 Activities)

Discover Target: MMP3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MMP8 Tchem Matrix metalloproteinase 8 (1942 Activities)

Discover Target: MMP8

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MMP1 Tchem Matrix metalloproteinase-1 (7046 Activities)

Discover Target: MMP1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

DAO Tchem D-amino-acid oxidase (802 Activities)

Discover Target: DAO

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Nos2 Nitric oxide synthase, inducible (3573 Activities)

Discover Target: Nos2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mmp2 Matrix metalloproteinase-2 (12 Activities)

Discover Target: Mmp2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mmp9 Matrix metalloproteinase 9 (38 Activities)

Discover Target: Mmp9

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

lef Anthrax lethal factor (7585 Activities)

Discover Target: lef

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	3-hydroxypyridine-2-carboxylic acid
INCHI	InChI=1S/C6H5NO3/c8-4-2-1-3-7-5(4)6(9)10/h1-3,8H,(H,9,10)
InChi Key	BRARRAHGNDUELT-UHFFFAOYSA-N
Canonical SMILES	C1=CC(=C(N=C1)C(=O)O)O
Isomeric SMILES	C1=CC(=C(N=C1)C(=O)O)O
WGK Germany	3
PubChem CID	13401
Molecular Weight	139.11
Beilstein	22(3/4)2134
Reaxy-Rn	118954

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

Melt Point(°C)	213-218 ℃

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
WGK Germany	3
Reaxy-Rn	118954

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Jingwei Wu, Man Qi, Gökalp Gözaydın, Ning Yan, Yongjun Gao, Xi Chen. (2021) Selectivity-Switchable Conversion of Chitin-Derived N-Acetyl-d-glucosamine into Commodity Organic Acids at Room Temperature. INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 60 (7): (3239–3248). [PMID:] [10.1021/acs.iecr.0c05805]
2. Hua Xia, Zhou Xin, Du GenLai, Xu Yong. (2020) Resolving the formidable barrier of oxygen transferring rate (OTR) in ultrahigh-titer bioconversion/biocatalysis by a sealed-oxygen supply biotechnology (SOS). Biotechnology for Biofuels, 13 (1): (1-12). [PMID:31911817] [10.1186/s13068-019-1642-1]
3. Jie Chai, Yanfei Liu, Jinglong Dong, Bin Liu, Binsheng Yang. (2017) Synthesis, structure, chemical and bioactivity behavior of eight chromium(III) picolinate derivatives Cr(R-pic)3. INORGANICA CHIMICA ACTA, 466 (151). [PMID:] [10.1016/j.ica.2017.05.041]

References

1. Jingwei Wu, Man Qi, Gökalp Gözaydın, Ning Yan, Yongjun Gao, Xi Chen. (2021) Selectivity-Switchable Conversion of Chitin-Derived N-Acetyl-d-glucosamine into Commodity Organic Acids at Room Temperature. INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 60 (7): (3239–3248). [PMID:] [10.1021/acs.iecr.0c05805]
2. Hua Xia, Zhou Xin, Du GenLai, Xu Yong. (2020) Resolving the formidable barrier of oxygen transferring rate (OTR) in ultrahigh-titer bioconversion/biocatalysis by a sealed-oxygen supply biotechnology (SOS). Biotechnology for Biofuels, 13 (1): (1-12). [PMID:31911817] [10.1186/s13068-019-1642-1]
3. Jie Chai, Yanfei Liu, Jinglong Dong, Bin Liu, Binsheng Yang. (2017) Synthesis, structure, chemical and bioactivity behavior of eight chromium(III) picolinate derivatives Cr(R-pic)3. INORGANICA CHIMICA ACTA, 466 (151). [PMID:] [10.1016/j.ica.2017.05.041]

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3-Hydroxy-2-pyridinecarboxylic acid - 10mM in DMSO, high purity , CAS No.874-24-8