3-iodothyronamine , CAS No.I607161, Agonist of TA 1 receptor

Item Number
I607161
Grouped product items
SKUSizeAvailabilityPrice Qty
I607161-25μg
25μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,334.90
I607161-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$3,334.90
View related series
TA1 receptor Agonist

Basic Description

Specifications & PurityMoligand™
GradeMoligand™
Action TypeAGONIST
Mechanism of actionAgonist of TA 1 receptor

Associated Targets(Human)

TAAR1 Tclin Trace amine-associated receptor 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 4-[4-(2-aminoethyl)phenoxy]-2-iodophenol
INCHI InChI=1S/C14H14INO2/c15-13-9-12(5-6-14(13)17)18-11-3-1-10(2-4-11)7-8-16/h1-6,9,17H,7-8,16H2
InChi Key HCYGDNGLWSZCCA-UHFFFAOYSA-N
Canonical SMILES NCCc1ccc(cc1)Oc1ccc(c(c1)I)O
Isomeric SMILES C1=CC(=CC=C1CCN)OC2=CC(=C(C=C2)O)I
PubChem CID 11501277

Certificates

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Related Documents

References

1. Scanlan TS, Suchland KL, Hart ME, Chiellini G, Huang Y, Kruzich PJ, Frascarelli S, Crossley DA, Bunzow JR, Ronca-Testoni S et al..  (2004)  3-Iodothyronamine is an endogenous and rapid-acting derivative of thyroid hormone..  Nat Med,  10  (6): (638-42).  [PMID:15146179] [10.1021/op500134e]
2. Hart ME, Suchland KL, Miyakawa M, Bunzow JR, Grandy DK, Scanlan TS.  (2006)  Trace amine-associated receptor agonists: synthesis and evaluation of thyronamines and related analogues..  J Med Chem,  49  (3): (1101-12).  [PMID:16451074] [10.1021/op500134e]

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