3-Morpholino Sydnonimine Hydrochloride - 98%, high purity , CAS No.16142-27-1

  • ≥98%
Item Number
M132410
Grouped product items
SKUSizeAvailabilityPrice Qty
M132410-5mg
5mg
In stock
$27.90
M132410-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$106.90
M132410-100mg
100mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$327.90

Vasodilator. Active metabolite of molsidomine.

Basic Description

Specifications & Purity≥98%
Biochemical and Physiological MechanismsSIN-1 chloride is an active metabolite of molsidomine, which is a potent vasorelaxant and inhibitor of platelet aggregation. It produces both NO and superoxide and can therefore be used to generate peroxynitrite under physiological conditions. SIN-1 decre
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
NoteIf possible, you try to configure the solution on the same day and use it on the same day. However, if you need to prepare a stock solution in advance, we recommend that you store aliquots of the solution in sealed vials at -20°C. Generally, they can be used for up to one month. Before use and before opening the sample vial, we recommend that you allow your product to equilibrate at room temperature for at least 1 hour.
Product Description

3-Morpholinosydnonimine hydrochloride is a metabolite of the vasodilator Molsidomine . It is considered to be a peroxynitrite releasing compound.

Associated Targets(Human)

POLB Tchem DNA polymerase beta (23632 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PLK1 Tchem Serine/threonine-protein kinase PLK1 (28605 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM4A Tchem Lysine-specific demethylase 4A (52245 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TRPC5 Tchem Short transient receptor potential channel 5 (300 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SMN1 Tchem Survival motor neuron protein (34246 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GMNN Tbio Geminin (128009 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BAZ2B Tchem Bromodomain adjacent to zinc finger domain protein 2B (56204 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TGR Thioredoxin glutathione reductase (28579 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mapt Microtubule-associated protein tau (6 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
mazF mRNA interferase MazF (968 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

Isomeric SMILES C1COCCN1[N+]2=CC(=N)O[N-]2.Cl
WGK Germany 3
PubChem CID 9859122
Molecular Weight 206.63

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

6 results found

Lot NumberCertificate TypeDateItem
F2413092Certificate of AnalysisJun 18, 2024 M132410
H2231554Certificate of AnalysisJun 18, 2024 M132410
H2231555Certificate of AnalysisJun 18, 2024 M132410
I2108302Certificate of AnalysisJun 15, 2023 M132410
D2307423Certificate of AnalysisJul 23, 2022 M132410
E2410030Certificate of AnalysisJul 23, 2022 M132410

Chemical and Physical Properties

SolubilityDMSO (Slightly), Methanol (Slightly), Water (Slightly)

Safety and Hazards(GHS)

Pictogram(s) GHS07
Hazard Statements

H302:Harmful if swallowed

WGK Germany 3

Related Documents

References

1. Machino H et al..  (2022)  The metabolic stress-activated checkpoint LKB1-MARK3 axis acts as a tumor suppressor in high-grade serous ovarian carcinoma..  Commun Biol,  (39).  [PMID:35017636]

Solution Calculators