Basic Description

Synonyms	3-Nitrophenol \| 554-84-7 \| M-NITROPHENOL \| 3-Hydroxynitrobenzene \| m-Hydroxynitrobenzene \| Phenol, 3-nitro- \| Phenol, m-nitro- \| m-Nitrofenol \| meta-Nitrophenol \| 3-nitro-phenol \| 1-Hydroxy-3-nitrobenzene \| NSC 1551 \| T6P4T52V9W \| DTXSID2025765 \| CHEBI:34346 \| NSC-1551 \| m-Nitrofenol [C
Specifications & Purity	analytical standard, ≥99%(GC)
Shipped In	Normal
Grade	analytical standard

Associated Targets(Human)

NR3C1 Tclin Glucocorticoid receptor (0 Activities)

Discover Target: NR3C1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PTH1R Tclin Parathyroid hormone/parathyroid hormone-related peptide receptor (0 Activities)

Discover Target: PTH1R

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

USP1 Tchem Ubiquitin carboxyl-terminal hydrolase 1 (0 Activities)

Discover Target: USP1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TSHR Tclin Thyrotropin receptor (0 Activities)

Discover Target: TSHR

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ALOX15 Tchem Arachidonate 15-lipoxygenase (0 Activities)

Discover Target: ALOX15

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (0 Activities)

Discover Target: TDP1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ALDH1A1 Tchem Retinal dehydrogenase 1 (0 Activities)

Discover Target: ALDH1A1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TARDBP Tchem TAR DNA-binding protein 43 (0 Activities)

Discover Target: TARDBP

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NFE2L2 Tchem Nuclear factor erythroid 2-related factor 2 (0 Activities)

Discover Target: NFE2L2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NR3C1 Tclin Glucocorticoid receptor (14987 Activities)

Discover Target: NR3C1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TSHR Tclin Thyroid stimulating hormone receptor (29986 Activities)

Discover Target: TSHR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PTH1R Tclin Parathyroid hormone receptor (47172 Activities)

Discover Target: PTH1R

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)

Discover Target: ALDH1A1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ALOX15 Tchem Arachidonate 15-lipoxygenase (7108 Activities)

Discover Target: ALOX15

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MIA PaCa-2 (5949 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)

Discover Target: TDP1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

USP1 Tchem Ubiquitin carboxyl-terminal hydrolase 1 (22556 Activities)

Discover Target: USP1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TARDBP Tchem TAR DNA-binding protein 43 (40113 Activities)

Discover Target: TARDBP

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Bacillus subtilis (32866 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Plasmodium falciparum (966862 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

L1210 (27553 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Colon (26 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)

Discover Target: Nfe2l2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	3-nitrophenol
INCHI	InChI=1S/C6H5NO3/c8-6-3-1-2-5(4-6)7(9)10/h1-4,8H
InChi Key	RTZZCYNQPHTPPL-UHFFFAOYSA-N
Canonical SMILES	C1=CC(=CC(=C1)O)[N+](=O)[O-]
Isomeric SMILES	C1=CC(=CC(=C1)O)[N+](=O)[O-]
WGK Germany	3
RTECS	SM1925000
PubChem CID	11137
UN Number	1663
Packing Group	III
Molecular Weight	139.11
Beilstein	1907946
Reaxy-Rn	1907946

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

3 results found

Lot Number	Certificate Type	Date	Item
I2224418	Certificate of Analysis	Jun 19, 2024	N100696
G1604078	Certificate of Analysis	Oct 19, 2023	N100696
B2010025	Certificate of Analysis	Sep 07, 2023	N100696

Chemical and Physical Properties

Solubility	Slightly soluble in water, soluble in ethanol, ether, acetone, dilute acids, alkalis, etc.
Sensitivity	Moisture sensitive.
Boil Point(°C)	194°C
Melt Point(°C)	96-97°C

Safety and Hazards(GHS)

Pictogram(s)	GHS05, GHS07
Signal	Danger
Hazard Statements	H315:Causes skin irritation H302:Harmful if swallowed H318:Causes serious eye damage H401:Toxic to aquatic life
Precautionary Statements	P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P270:Do not eat, drink or smoke when using this product. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. P317:Get emergency medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
WGK Germany	3
RTECS	SM1925000
Reaxy-Rn	1907946
Class	6.1
Merck Index	6618

Citations of This Product

1. Jiannan Chen, Xiuhua Xia, Peizhen Li, Hang Yu, Yunfei Xie, Yahui Guo, Weirong Yao, He Qian, Yuliang Cheng. (2023) Crayfish shells-derived carbon dots as a fluorescence sensor for the selective detection of 4-nitrophenol. FOOD AND AGRICULTURAL IMMUNOLOGY, [PMID:]
2. Xing Jiali, Xu Xiaorong, Li Yang, Chen Cancan, Mao Lingyan, Luo Xiaohu, Shen Jian, Cheng Hai, Zhang Shufen, Guo Yahui, Gan Ning. (2023) Simultaneous detection of multiple phenolic compounds in shrimps through gas chromatography–mass spectrometry coupled with a modified QuEChERS. EUROPEAN FOOD RESEARCH AND TECHNOLOGY, (1-15). [PMID:]
3. Yao An, Zhaoxiang Yang, Yongjia Yang, Xinlei Li, Xinjia Zheng, Zhiwu Chen, Xun Wu, Beihang Xu, Yapei Wang, Yonglin He. (2023) Stretchable, Programmable and Magnet-Insensitive Protonic Display Based on Integrated Ionic Circuit. Small, 20 (11): (2308875). [PMID:37880900]
4. Guoqiang Guo, Tingting Li, Ziyi Liu, Xinyu Luo, Ting Zhang, Siyuan Tang, Xu Wang, Da Chen. (2024) Bell pepper derived nitrogen-doped carbon dots as a pH-modulated fluorescence switching sensor with high sensitivity for visual sensing of 4-nitrophenol. FOOD CHEMISTRY, 432 (137232). [PMID:37633140]
5. Xuan Zhao, Xiaolong Zeng, Xinyu Wu, Lihong Shi, Sumin Zhu, Wen Sun. (2023) A GSH-Activatable Theranostic Prodrug Based on Photoinduced Electron Transfer for Cancer Fluorescence Imaging and Therapy. Chemosensors, 11 (7): (397). [PMID:]
6. Libao Han, Minghuo Wu, Yufeng Hu. (2023) Colorimetric Detection of Multiple Phenols Based on Multifunctional Fe3O4/SnS2 Composites. ChemPlusChem, 88 (7): (e202300247). [PMID:37414731]
7. Baocheng Zhou, Ying Liu, Wei Zhao, Changhao Bian, Pengfei Sun. (2023) Graphitic carbon nitride modified by 5-sulfonic-8-hydroxyquinoline and Fe (III) ions as visible-light photocatalyst to efficiently reduce nitroaromatic compounds. Journal of Environmental Chemical Engineering, 11 (110282). [PMID:]
8. Li Sun, Mengying Sun, Yuan Zhi, Hua Zhang, Yuejin Shan, Binlin Dou, Jian Chen, Lixin Zhang. (2023) High-efficiency reactor and its tandem module with Au–Co–CoOx-coated glass beads for continuous-flow reduction of dyeing wastewater. Reaction Chemistry & Engineering, 8 (8): (1981-1992). [PMID:]
9. Ling Lei, Jiaxi Yin, Kangbing Wu, Nianjun Yang. (2023) Size-Dependent Electrochemistry of Oxygenated Ti3C2Tx MXenes. Small Methods, 7 (6): (2300302). [PMID:36998117]
10. Yi Wang, Xueke Wu, Chengpei Du, Kanglin Pei, Di Wu, Jianping Lai, Wenjing Qi. (2023) A fast and highly efficient strategy for discrimination and detection of three nitrophenol isomers. SENSORS AND ACTUATORS B-CHEMICAL, 383 (133572). [PMID:]
11. Kunpeng Wang, Liju Tan, Yuewei Zhang, Dongmei Zhang, Na Wang, Jiangtao Wang. (2023) A molecular imprinted fluorescence sensor based on carbon quantum dots for selective detection of 4-nitrophenol in aqueous environments. MARINE POLLUTION BULLETIN, 187 (114587). [PMID:36669299]
12. Yahan Yu, Chunxiu Yu, Zelin Wu, Bingkun Huang, Peng Zhou, Heng Zhang, Wen Liu, Yucheng Liu, Zhaokun Xiong, Bo Lai. (2023) Switching the primary mechanism from a radical to a nonradical pathway in electrocatalytic ozonation by onsite alternating anode and cathode. CHEMICAL ENGINEERING JOURNAL, 457 (141340). [PMID:]
13. Mengzhen Ren, Yujie Zhang, Lanlan Yu, Lingbo Qu, Zhaohui Li, Lin Zhang. (2023) A Co-based MOF as nanozyme with enhanced oxidase-like activity for highly sensitive and selective colorimetric differentiation of aminophenol isomers. TALANTA, 255 (124219). [PMID:36580809]
14. Jiao Luo, Hongyan Tan, Bin Yang, Donghua Chen, Junjie Fei. (2022) A mesoporous silica-based probe with a molecularly imprinted polymer recognition and Mn:ZnS QDs@rhodamine B ratiometric fluorescence sensing strategy for the analysis of 4-nitrophenol. Analytical Methods, 14 (39): (3881-3889). [PMID:36156613]
15. Ying Zhu, Zhiying Feng, Zihao Yan, Xiaoming Yang. (2022) Promoting the transfer of phosphorescence from the solid state to aqueous phase and establishing the universal real-time detection based on the smartphone imaging. SENSORS AND ACTUATORS B-CHEMICAL, 371 (132529). [PMID:]
16. Qinglin Wang, Zhuojun Wei, Jin Li, Danyang Feng, An Feng, Hui Zhang. (2022) Hierarchical-Structured Pd Nanoclusters Catalysts x-PdNCs/CoAl(O)/rGO-T by the Captopril-Capped Pd Cluster Precursor Method for the Highly Efficient 4-Nitrophenol Reduction. ACS Applied Materials & Interfaces, 14 (24): (27775–27790). [PMID:35679591]
17. Liang Zhu, Xuecui Mei, Zhengchun Peng, Jiao Yang, Yingchun Li. (2022) A paper-based microfluidic sensor array combining molecular imprinting technology and carbon quantum dots for the discrimination of nitrophenol isomers. JOURNAL OF HAZARDOUS MATERIALS, 435 (129012). [PMID:35504132]
18. Jiali Xing, Yang Li, Ruihang Zheng, Hao Shen, Xiaorong Xu, Lingyan Mao, Xiaohu Luo, Jian Shen, Weirong Yao. (2022) Simultaneous detection of multiple phenolic compounds in fish by gas chromatography-mass spectrometry following a modified QuEChERS cleanup. Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment, 39 (6): (1136-1148). [PMID:35442851]
19. Hai-Bo Wang, Bei-Bei Tao, Ning-Ning Wu, Hong-Ding Zhang, Yan-Ming Liu. (2022) Glutathione-stabilized copper nanoclusters mediated-inner filter effect for sensitive and selective determination of p-nitrophenol and alkaline phosphatase activity. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 271 (120948). [PMID:35104744]
20. Xu Yeqing, Huang Ting, Meng Minjia, Yan Yongsheng. (2022) Fluorescent polydopamine based molecularly imprinted sensor for ultrafast and selective detection of p-nitrophenol in drinking water. MICROCHIMICA ACTA, 189 (1): (1-13). [PMID:34897555]
21. Qishu Qu,Han Xuan,Kehua Zhang,Yi Ding,Qin Xu. (2016-05-14) Layer-by-layer assembly of zeolite imidazolate framework-8 as coating material for capillary electrochromatography.. Electrophoresis, 37 ((15-16)): (2175-2180). [PMID:27174427]
22. Hao Dai,Ziyi Deng,Yanbo Zeng,Jian Zhang,Yiwen Yang,Qinyan Ma,Wenling Hu,Longhua Guo,Lei Li,Shulin Wan,Haiying Liu. (2020-06-07) Highly sensitive determination of 4-nitrophenol with coumarin-based fluorescent molecularly imprinted poly (ionic liquid).. Journal of hazardous materials, 398 (122854-122854). [PMID:32504958]

References

1. Jiannan Chen, Xiuhua Xia, Peizhen Li, Hang Yu, Yunfei Xie, Yahui Guo, Weirong Yao, He Qian, Yuliang Cheng. (2023) Crayfish shells-derived carbon dots as a fluorescence sensor for the selective detection of 4-nitrophenol. FOOD AND AGRICULTURAL IMMUNOLOGY, [PMID:]
2. Xing Jiali, Xu Xiaorong, Li Yang, Chen Cancan, Mao Lingyan, Luo Xiaohu, Shen Jian, Cheng Hai, Zhang Shufen, Guo Yahui, Gan Ning. (2023) Simultaneous detection of multiple phenolic compounds in shrimps through gas chromatography–mass spectrometry coupled with a modified QuEChERS. EUROPEAN FOOD RESEARCH AND TECHNOLOGY, (1-15). [PMID:]
3. Yao An, Zhaoxiang Yang, Yongjia Yang, Xinlei Li, Xinjia Zheng, Zhiwu Chen, Xun Wu, Beihang Xu, Yapei Wang, Yonglin He. (2023) Stretchable, Programmable and Magnet-Insensitive Protonic Display Based on Integrated Ionic Circuit. Small, 20 (11): (2308875). [PMID:37880900]
4. Guoqiang Guo, Tingting Li, Ziyi Liu, Xinyu Luo, Ting Zhang, Siyuan Tang, Xu Wang, Da Chen. (2024) Bell pepper derived nitrogen-doped carbon dots as a pH-modulated fluorescence switching sensor with high sensitivity for visual sensing of 4-nitrophenol. FOOD CHEMISTRY, 432 (137232). [PMID:37633140]
5. Xuan Zhao, Xiaolong Zeng, Xinyu Wu, Lihong Shi, Sumin Zhu, Wen Sun. (2023) A GSH-Activatable Theranostic Prodrug Based on Photoinduced Electron Transfer for Cancer Fluorescence Imaging and Therapy. Chemosensors, 11 (7): (397). [PMID:]
6. Libao Han, Minghuo Wu, Yufeng Hu. (2023) Colorimetric Detection of Multiple Phenols Based on Multifunctional Fe3O4/SnS2 Composites. ChemPlusChem, 88 (7): (e202300247). [PMID:37414731]
7. Baocheng Zhou, Ying Liu, Wei Zhao, Changhao Bian, Pengfei Sun. (2023) Graphitic carbon nitride modified by 5-sulfonic-8-hydroxyquinoline and Fe (III) ions as visible-light photocatalyst to efficiently reduce nitroaromatic compounds. Journal of Environmental Chemical Engineering, 11 (110282). [PMID:]
8. Li Sun, Mengying Sun, Yuan Zhi, Hua Zhang, Yuejin Shan, Binlin Dou, Jian Chen, Lixin Zhang. (2023) High-efficiency reactor and its tandem module with Au–Co–CoOx-coated glass beads for continuous-flow reduction of dyeing wastewater. Reaction Chemistry & Engineering, 8 (8): (1981-1992). [PMID:]
9. Ling Lei, Jiaxi Yin, Kangbing Wu, Nianjun Yang. (2023) Size-Dependent Electrochemistry of Oxygenated Ti3C2Tx MXenes. Small Methods, 7 (6): (2300302). [PMID:36998117]
10. Yi Wang, Xueke Wu, Chengpei Du, Kanglin Pei, Di Wu, Jianping Lai, Wenjing Qi. (2023) A fast and highly efficient strategy for discrimination and detection of three nitrophenol isomers. SENSORS AND ACTUATORS B-CHEMICAL, 383 (133572). [PMID:]
11. Kunpeng Wang, Liju Tan, Yuewei Zhang, Dongmei Zhang, Na Wang, Jiangtao Wang. (2023) A molecular imprinted fluorescence sensor based on carbon quantum dots for selective detection of 4-nitrophenol in aqueous environments. MARINE POLLUTION BULLETIN, 187 (114587). [PMID:36669299]
12. Yahan Yu, Chunxiu Yu, Zelin Wu, Bingkun Huang, Peng Zhou, Heng Zhang, Wen Liu, Yucheng Liu, Zhaokun Xiong, Bo Lai. (2023) Switching the primary mechanism from a radical to a nonradical pathway in electrocatalytic ozonation by onsite alternating anode and cathode. CHEMICAL ENGINEERING JOURNAL, 457 (141340). [PMID:]
13. Mengzhen Ren, Yujie Zhang, Lanlan Yu, Lingbo Qu, Zhaohui Li, Lin Zhang. (2023) A Co-based MOF as nanozyme with enhanced oxidase-like activity for highly sensitive and selective colorimetric differentiation of aminophenol isomers. TALANTA, 255 (124219). [PMID:36580809]
14. Jiao Luo, Hongyan Tan, Bin Yang, Donghua Chen, Junjie Fei. (2022) A mesoporous silica-based probe with a molecularly imprinted polymer recognition and Mn:ZnS QDs@rhodamine B ratiometric fluorescence sensing strategy for the analysis of 4-nitrophenol. Analytical Methods, 14 (39): (3881-3889). [PMID:36156613]
15. Ying Zhu, Zhiying Feng, Zihao Yan, Xiaoming Yang. (2022) Promoting the transfer of phosphorescence from the solid state to aqueous phase and establishing the universal real-time detection based on the smartphone imaging. SENSORS AND ACTUATORS B-CHEMICAL, 371 (132529). [PMID:]
16. Qinglin Wang, Zhuojun Wei, Jin Li, Danyang Feng, An Feng, Hui Zhang. (2022) Hierarchical-Structured Pd Nanoclusters Catalysts x-PdNCs/CoAl(O)/rGO-T by the Captopril-Capped Pd Cluster Precursor Method for the Highly Efficient 4-Nitrophenol Reduction. ACS Applied Materials & Interfaces, 14 (24): (27775–27790). [PMID:35679591]
17. Liang Zhu, Xuecui Mei, Zhengchun Peng, Jiao Yang, Yingchun Li. (2022) A paper-based microfluidic sensor array combining molecular imprinting technology and carbon quantum dots for the discrimination of nitrophenol isomers. JOURNAL OF HAZARDOUS MATERIALS, 435 (129012). [PMID:35504132]
18. Jiali Xing, Yang Li, Ruihang Zheng, Hao Shen, Xiaorong Xu, Lingyan Mao, Xiaohu Luo, Jian Shen, Weirong Yao. (2022) Simultaneous detection of multiple phenolic compounds in fish by gas chromatography-mass spectrometry following a modified QuEChERS cleanup. Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment, 39 (6): (1136-1148). [PMID:35442851]
19. Hai-Bo Wang, Bei-Bei Tao, Ning-Ning Wu, Hong-Ding Zhang, Yan-Ming Liu. (2022) Glutathione-stabilized copper nanoclusters mediated-inner filter effect for sensitive and selective determination of p-nitrophenol and alkaline phosphatase activity. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 271 (120948). [PMID:35104744]
20. Xu Yeqing, Huang Ting, Meng Minjia, Yan Yongsheng. (2022) Fluorescent polydopamine based molecularly imprinted sensor for ultrafast and selective detection of p-nitrophenol in drinking water. MICROCHIMICA ACTA, 189 (1): (1-13). [PMID:34897555]
21. Qishu Qu,Han Xuan,Kehua Zhang,Yi Ding,Qin Xu. (2016-05-14) Layer-by-layer assembly of zeolite imidazolate framework-8 as coating material for capillary electrochromatography.. Electrophoresis, 37 ((15-16)): (2175-2180). [PMID:27174427]
22. Hao Dai,Ziyi Deng,Yanbo Zeng,Jian Zhang,Yiwen Yang,Qinyan Ma,Wenling Hu,Longhua Guo,Lei Li,Shulin Wan,Haiying Liu. (2020-06-07) Highly sensitive determination of 4-nitrophenol with coumarin-based fluorescent molecularly imprinted poly (ionic liquid).. Journal of hazardous materials, 398 (122854-122854). [PMID:32504958]

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3-Nitrophenol - analytical standard，>99%(GC), high purity , CAS No.554-84-7