Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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N106587-100mg | 100mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $27.90 | |
N106587-200mg | 200mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $105.90 | |
N106587-250mg | 250mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $41.90 | |
N106587-1g | 1g | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $119.90 | |
N106587-5g | 5g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $419.90 |
Selective, irreversible succinic dehydrogenase (complex II) inhibitor.
Synonyms | 3-nitropropionic acid | 3-Nitropropanoic acid | 504-88-1 | Bovinocidin | Hiptagenic acid | beta-Nitropropionic acid | 3-Nitropropionate | Propanoic acid, 3-nitro- | Propionic acid, 3-nitro- | 3-NP acid | beta-Nitropropanoic acid | NCI-C03076 | NSC 64266 | 3-nitro-propionic acid | BO |
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Specifications & Purity | ≥97% |
Biochemical and Physiological Mechanisms | 3-Nitropropionic acid is a potent irreversible inhibitor of mitochondrial complex II enzyme, which causes dysfunction and oxidative stress in mitochondria. 3-Nitropropionic acid is an important research compound because it can simulate the effects on cell |
Storage Temp | Store at 2-8°C,Protected from light,Argon charged |
Shipped In | Wet ice |
Note | 200mg 售完停产 Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Excitotoxin shown to cause brain lesions similar to those of Huntington′s disease.3-Nitropropionic acid (β-Nitropropionic Acid, 3-NP) is an irreversible inhibitor of mitochondrial respiratory Complex II succinate dehydrogenase, resulting in energy depletion through disruption of the electron transport chain. |
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IUPAC Name | 3-nitropropanoic acid |
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INCHI | InChI=1S/C3H5NO4/c5-3(6)1-2-4(7)8/h1-2H2,(H,5,6) |
InChi Key | WBLZUCOIBUDNBV-UHFFFAOYSA-N |
Canonical SMILES | C(C[N+](=O)[O-])C(=O)O |
Isomeric SMILES | C(C[N+](=O)[O-])C(=O)O |
WGK Germany | 3 |
RTECS | UF6220000 |
PubChem CID | 1678 |
UN Number | 2811 |
Packing Group | I |
Molecular Weight | 119.08 |
Beilstein | 1759889 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
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H2402536 | Certificate of Analysis | Jul 19, 2024 | N106587 |
H2402535 | Certificate of Analysis | Jul 19, 2024 | N106587 |
H2402534 | Certificate of Analysis | Jul 19, 2024 | N106587 |
D2428383 | Certificate of Analysis | Mar 12, 2024 | N106587 |
C2401398 | Certificate of Analysis | Feb 04, 2024 | N106587 |
C2401399 | Certificate of Analysis | Feb 04, 2024 | N106587 |
C2401400 | Certificate of Analysis | Feb 04, 2024 | N106587 |
C2401401 | Certificate of Analysis | Feb 04, 2024 | N106587 |
C2401402 | Certificate of Analysis | Feb 04, 2024 | N106587 |
C2401405 | Certificate of Analysis | Feb 04, 2024 | N106587 |
C2401406 | Certificate of Analysis | Feb 04, 2024 | N106587 |
G2402129 | Certificate of Analysis | Feb 04, 2024 | N106587 |
D2311876 | Certificate of Analysis | Feb 10, 2023 | N106587 |
D2312753 | Certificate of Analysis | Feb 10, 2023 | N106587 |
D2311902 | Certificate of Analysis | Feb 10, 2023 | N106587 |
D2311880 | Certificate of Analysis | Feb 10, 2023 | N106587 |
B2427589 | Certificate of Analysis | Feb 10, 2023 | N106587 |
B2427590 | Certificate of Analysis | Feb 10, 2023 | N106587 |
Sensitivity | Light sensitive;Moisture sensitive |
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Melt Point(°C) | 68-70°C |
Pictogram(s) | GHS06, GHS07 |
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Signal | Danger |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H301:Toxic if swallowed |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
WGK Germany | 3 |
RTECS | UF6220000 |
Class | 6.1 |
Starting at $134.90