Grouped product items

SKU

Size

Availability

Price

Qty

N106587-100mg

100mg

Available within 4-8 weeks(?)

$27.90

N106587-200mg

200mg

Available within 8-12 weeks(?)

$105.90

N106587-250mg

250mg

Available within 8-12 weeks(?)

$41.90

N106587-1g

Available within 8-12 weeks(?)

$119.90

N106587-5g

Available within 4-8 weeks(?)

$419.90

Basic Description

Synonyms	3-NP \| Bovinocidin \| 3-NP acid \| β-Nitropropionic acid
Specifications & Purity	≥97%
Biochemical and Physiological Mechanisms	3-Nitropropionic acid is a potent irreversible inhibitor of mitochondrial complex II enzyme, which causes dysfunction and oxidative stress in mitochondria. 3-Nitropropionic acid is an important research compound because it can simulate the effects on cell
Storage Temp	Store at 2-8°C,Protected from light,Argon charged
Shipped In	Wet ice
Note	200mg 售完停产 Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description	Excitotoxin shown to cause brain lesions similar to those of Huntington′s disease.3-Nitropropionic acid (β-Nitropropionic Acid, 3-NP) is an irreversible inhibitor of mitochondrial respiratory Complex II succinate dehydrogenase, resulting in energy depletion through disruption of the electron transport chain.

Associated Targets(Human)

CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)

Discover Target: CHRM1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP2D6 Tclin Cytochrome P450 2D6 (33882 Activities)

Discover Target: CYP2D6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HBB Tbio Hemoglobin beta chain (329 Activities)

Discover Target: HBB

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP1A2 Tchem Cytochrome P450 1A2 (26471 Activities)

Discover Target: CYP1A2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP2C9 Tchem Cytochrome P450 2C9 (32119 Activities)

Discover Target: CYP2C9

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP2C19 Tchem Cytochrome P450 2C19 (29246 Activities)

Discover Target: CYP2C19

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)

Discover Target: CYP3A4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HepG2 (196354 Activities)

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KB (17409 Activities)

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HIF1A Tchem Hypoxia-inducible factor 1 alpha (6027 Activities)

Discover Target: HIF1A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

POLI Tchem DNA polymerase iota (116820 Activities)

Discover Target: POLI

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)

Discover Target: EHMT2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

LMNA Tbio Prelamin-A/C (36751 Activities)

Discover Target: LMNA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

BLM Tchem Bloom syndrome protein (4248 Activities)

Discover Target: BLM

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GMNN Tbio Geminin (128009 Activities)

Discover Target: GMNN

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CBX1 Tbio Chromobox protein homolog 1 (92434 Activities)

Discover Target: CBX1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MEN1 Tchem Menin/Histone-lysine N-methyltransferase MLL (48157 Activities)

Discover Target: MEN1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TARDBP Tchem TAR DNA-binding protein 43 (40113 Activities)

Discover Target: TARDBP

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

NCI-H187 (598 Activities)

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Associated Targets(non-human)

Mycobacterium avium (4587 Activities)

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Mycobacterium kansasii (6484 Activities)

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Mycobacterium tuberculosis (203094 Activities)

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Mycolicibacterium smegmatis (8003 Activities)

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Aspergillus fumigatus (16427 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Candida albicans (78123 Activities)

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Trichophyton rubrum (3646 Activities)

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Vero (26788 Activities)

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ICL1 Isocitrate lyase (219 Activities)

Discover Target: ICL1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)

Discover Target: Txnrd1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Trichophyton mentagrophytes (4846 Activities)

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Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)

Discover Target: Nfe2l2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

icl1 Isocitrate lyase 1 (45 Activities)

Discover Target: icl1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	3-nitropropanoic acid
INCHI	InChI=1S/C3H5NO4/c5-3(6)1-2-4(7)8/h1-2H2,(H,5,6)
InChi Key	WBLZUCOIBUDNBV-UHFFFAOYSA-N
Canonical SMILES	C(C[N+](=O)[O-])C(=O)O
Isomeric SMILES	C(C[N+](=O)[O-])C(=O)O
WGK Germany	3
RTECS	UF6220000
PubChem CID	1678
UN Number	2811
Packing Group	I
Molecular Weight	119.08
Beilstein	1759889

Certificates

Certificate of Analysis(COA)

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Find and download the COA for your product by matching the lot number on the packaging.

18 results found

Lot Number	Certificate Type	Date	Item
H2402536	Certificate of Analysis	Jul 19, 2024	N106587
H2402535	Certificate of Analysis	Jul 19, 2024	N106587
H2402534	Certificate of Analysis	Jul 19, 2024	N106587
D2428383	Certificate of Analysis	Mar 12, 2024	N106587
C2401398	Certificate of Analysis	Feb 04, 2024	N106587
C2401399	Certificate of Analysis	Feb 04, 2024	N106587
C2401400	Certificate of Analysis	Feb 04, 2024	N106587
C2401401	Certificate of Analysis	Feb 04, 2024	N106587
C2401402	Certificate of Analysis	Feb 04, 2024	N106587
C2401405	Certificate of Analysis	Feb 04, 2024	N106587
C2401406	Certificate of Analysis	Feb 04, 2024	N106587
G2402129	Certificate of Analysis	Feb 04, 2024	N106587
D2311876	Certificate of Analysis	Feb 10, 2023	N106587
D2312753	Certificate of Analysis	Feb 10, 2023	N106587
D2311902	Certificate of Analysis	Feb 10, 2023	N106587
D2311880	Certificate of Analysis	Feb 10, 2023	N106587
B2427589	Certificate of Analysis	Feb 10, 2023	N106587
B2427590	Certificate of Analysis	Feb 10, 2023	N106587

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Chemical and Physical Properties

Sensitivity	Light sensitive;Moisture sensitive
Melt Point(°C)	68-70°C

Safety and Hazards(GHS)

Pictogram(s)	GHS06, GHS07
Signal	Danger
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H301:Toxic if swallowed
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
WGK Germany	3
RTECS	UF6220000
Class	6.1

Alternative Products

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Shanshan Wang, Qifeng Li, Fanghui Wang. (2020) The effect of imidazolated PPO with different alkyl chains on its performance as a high temperature proton exchange membrane. Polymer-Plastics Technology and Materials, [PMID:] [10.1080/25740881.2020.1750650]
2. Suxia Wang, Min Zhou, Yongxi Zhu, Bo Peng, Jia Yang, Yongjun Ma. (2020) Voltammetric Detection of 3-Nitropropionic Acid in Sugarcane Juices Using a Poly(L-citrulline)/Lanthanide-Containing Cyano-Bridged Heterometallic Coordination Polymer Modified Electrode. JOURNAL OF THE ELECTROCHEMICAL SOCIETY, 167 (8): (86508). [PMID:] [10.1149/1945-7111/ab8ece]

References

1. Shanshan Wang, Qifeng Li, Fanghui Wang. (2020) The effect of imidazolated PPO with different alkyl chains on its performance as a high temperature proton exchange membrane. Polymer-Plastics Technology and Materials, [PMID:] [10.1080/25740881.2020.1750650]
2. Suxia Wang, Min Zhou, Yongxi Zhu, Bo Peng, Jia Yang, Yongjun Ma. (2020) Voltammetric Detection of 3-Nitropropionic Acid in Sugarcane Juices Using a Poly(L-citrulline)/Lanthanide-Containing Cyano-Bridged Heterometallic Coordination Polymer Modified Electrode. JOURNAL OF THE ELECTROCHEMICAL SOCIETY, 167 (8): (86508). [PMID:] [10.1149/1945-7111/ab8ece]

Solution Calculators

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3-Nitropropionic acid - 97%, high purity , CAS No.504-88-1

Basic Description

Associated Targets(Human)

Associated Targets(non-human)

Mechanisms of Action

Names and Identifiers

Certificates

Certificate of Analysis(COA)

Show more⌵

Chemical and Physical Properties

Safety and Hazards(GHS)

Related Documents

Alternative Products

Citations of This Product

References

Solution Calculators

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

SKU	Size	Availability	Price
N106587-100mg	100mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$27.90
N106587-200mg	200mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$105.90
N106587-250mg	250mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$41.90
N106587-1g	1g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$119.90
N106587-5g	5g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$419.90