3-Nitropropionic acid is a potent irreversible inhibitor of mitochondrial complex II enzyme, which causes dysfunction and oxidative stress in mitochondria. 3-Nitropropionic acid is an important research compound because it can simulate the effects on cell
Storage Temp
Store at -80°C
Shipped In
Ice chest + Ice pads
Note
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description
Excitotoxin shown to cause brain lesions similar to those of Huntington′s disease.3-Nitropropionic acid (β-Nitropropionic Acid, 3-NP) is an irreversible inhibitor of mitochondrial respiratory Complex II succinate dehydrogenase, resulting in energy depletion through disruption of the electron transport chain.
1.Suxia Wang, Min Zhou, Yongxi Zhu, Bo Peng, Jia Yang, Yongjun Ma. (2020) Voltammetric Detection of 3-Nitropropionic Acid in Sugarcane Juices Using a Poly(L-citrulline)/Lanthanide-Containing Cyano-Bridged Heterometallic Coordination Polymer Modified Electrode. JOURNAL OF THE ELECTROCHEMICAL SOCIETY, 167 (8):(86508). [PMID:][10.1149/1945-7111/ab8ece]
References
1.Suxia Wang, Min Zhou, Yongxi Zhu, Bo Peng, Jia Yang, Yongjun Ma. (2020) Voltammetric Detection of 3-Nitropropionic Acid in Sugarcane Juices Using a Poly(L-citrulline)/Lanthanide-Containing Cyano-Bridged Heterometallic Coordination Polymer Modified Electrode. JOURNAL OF THE ELECTROCHEMICAL SOCIETY, 167 (8):(86508). [PMID:][10.1149/1945-7111/ab8ece]
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