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3M-002 , CAS No.M607166, Agonist of TLR8

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3M-002 , CAS No.M607166, Agonist of TLR8

Moligand™

PubChem CID: 10198719

Item Number

M607166

Grouped product items
SKU	Size	Availability	Price	Qty
M607166-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,334.90
M607166-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,001.90

View related series

TLR8 Agonist

Basic Description

Synonyms	2-propylthiazolo[4,5-c]quinolin-4-amine \| 256922-53-9 \| CL075 \| CL-075 \| CHEMBL512901 \| 3M-002 \| 2-Propyl[1,3]thiazolo[4,5-C]quinolin-4-Amine \| 2-PROPYL-[1,3]THIAZOLO[4,5-C]QUINOLIN-4-AMINE \| L07 \| CL 075 \| SCHEMBL482958 \| GTPL9270 \| DTXSID80436686 \| NFYMGJSUKCDVJR-UHFFFAOYSA-N \| EX
Specifications & Purity	Moligand™
Grade	Moligand™
Action Type	AGONIST
Mechanism of action	Agonist of TLR8

Associated Targets(Human)

TLR8 Tchem Toll-like receptor 8 (1 Activities)

Discover Target: TLR8

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PBMC (10003 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TLR8 Tchem Toll-like receptor 8 (1853 Activities)

Discover Target: TLR8

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Human immunodeficiency virus 1 (70413 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Hepatitis C virus (23859 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Tlr7 Toll-like receptor 7 (174 Activities)

Discover Target: Tlr7

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	2-propyl-[1,3]thiazolo[4,5-c]quinolin-4-amine
INCHI	InChI=1S/C13H13N3S/c1-2-5-10-16-11-12(17-10)8-6-3-4-7-9(8)15-13(11)14/h3-4,6-7H,2,5H2,1H3,(H2,14,15)
InChi Key	NFYMGJSUKCDVJR-UHFFFAOYSA-N
Canonical SMILES	CCCc1nc2c(s1)c1ccccc1nc2N
Isomeric SMILES	CCCC1=NC2=C(S1)C3=CC=CC=C3N=C2N
PubChem CID	10198719

Database links

PubChem CID	10198719
ChEMBL Ligand	CHEMBL512901
RCSB PDB Ligand	L07

Certificates

Certificate of Analysis(COA)

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References

1. Gorden KB, Gorski KS, Gibson SJ, Kedl RM, Kieper WC, Qiu X, Tomai MA, Alkan SS, Vasilakos JP. (2005) Synthetic TLR agonists reveal functional differences between human TLR7 and TLR8.. J Immunol, 174 (3): (1259-68). [PMID:15661881] [10.1021/op500134e]

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3M-002 , CAS No.M607166, Agonist of TLR8

Basic Description

Associated Targets(Human)

Associated Targets(non-human)

Mechanisms of Action

Names and Identifiers

Database links

Certificates

Certificate of Analysis(COA)

Related Documents

References

Solution Calculators

Molarity Calculator

Dilution Calculator

Reconstitution Calculator