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4-(2-Aminoethyl)morpholine - 98%, high purity , CAS No.2038-03-1

7 Citations

≥98%

CAS#: 2038-03-1
Formula: C₆H₁₄N₂O
Molecular Weight: 130.19
Beilstein Registry Number: 104378
EC Number: 218-011-6
MDL number: MFCD00006182
PubChem CID: 408285
PubChem SID: 488189685

Item Number

M108995

Grouped product items
SKU	Size	Availability	Price
M108995-5g	5g	In stock	$9.90
M108995-25g	25g	In stock	$34.90
M108995-100g	100g	In stock	$95.90
M108995-500g	500g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$263.90

Basic Description

Synonyms	2-(morpholin-4-yl)ethaneamine \| morpholinoethyl amine \| DTXCID2024408 \| EN300-20345 \| 2-morpholin-4-ylethylamine \| 2-Morpholin-4-yl-ethylamine \| 4-2-Aminoethyl-morpholine \| Boc-L-asparticacid?-9-fluorenylmethylester \| BP-10332 \| 2-(4-Morpholinyl)ethanamin
Specifications & Purity	≥98%
Storage Temp	Room temperature
Shipped In	Normal

Associated Targets(Human)

CA2 Tclin Carbonic anhydrase II (17698 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CA3 Tclin Carbonic anhydrase III (753 Activities)

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CA6 Tclin Carbonic anhydrase VI (993 Activities)

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CA1 Tclin Carbonic anhydrase I (13240 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CA5B Tclin Carbonic anhydrase VB (957 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CA5A Tclin Carbonic anhydrase VA (1168 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CA14 Tclin Carbonic anhydrase XIV (1305 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CA12 Tclin Carbonic anhydrase XII (6231 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CA9 Tclin Carbonic anhydrase IX (8255 Activities)

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Associated Targets(non-human)

Ca7 Carbonic anhydrase VII (3 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Ca13 Carbonic anhydrase XIII (322 Activities)

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CA4 Carbonic anhydrase IV (1713 Activities)

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Carbonic anhydrase (69 Activities)

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Ca15 Carbonic anhydrase 15 (173 Activities)

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CAN2 Carbonic anhydrase 2 (140 Activities)

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Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

Pubchem Sid	488189685
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488189685
IUPAC Name	2-morpholin-4-ylethanamine
INCHI	InChI=1S/C6H14N2O/c7-1-2-8-3-5-9-6-4-8/h1-7H2
InChi Key	RWIVICVCHVMHMU-UHFFFAOYSA-N
Canonical SMILES	C1COCCN1CCN
Isomeric SMILES	C1COCCN1CCN
WGK Germany	2
RTECS	QD7350000
PubChem CID	408285
UN Number	2735
Molecular Weight	130.19
Beilstein	104378
Reaxy-Rn	104378

Certificates

Certificate of Analysis(COA)

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5 results found

Lot Number	Certificate Type	Date	Item
B2223043	Certificate of Analysis	Jan 13, 2022	M108995
B2222578	Certificate of Analysis	Dec 30, 2021	M108995
B2223015	Certificate of Analysis	Dec 30, 2021	M108995
B2223041	Certificate of Analysis	Dec 30, 2021	M108995
B2226045	Certificate of Analysis	Dec 30, 2021	M108995

Chemical and Physical Properties

Solubility	Miscible with water.
Freezing Point(°C)	25 °C
Refractive Index	1.4745-1.4765
Flash Point(°F)	186.8 °F
Flash Point(°C)	175℃
Boil Point(°C)	205°C
Melt Point(°C)	24°C

Safety and Hazards(GHS)

Pictogram(s)	GHS06, GHS05, GHS07
Signal	Danger
Hazard Statements	H311:Toxic in contact with skin H314:Causes severe skin burns and eye damage H302:Harmful if swallowed H318:Causes serious eye damage H317:May cause an allergic skin reaction
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P270:Do not eat, drink or smoke when using this product. P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P363:Wash contaminated clothing before reuse. P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P361+P364:Take off immediately all contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. P317:Get emergency medical help. P302+P361+P354:IF ON SKIN: Take off Immediately all contaminated clothing. Immediately rinse with water for several minutes. P316:Get emergency medical help immediately.
WGK Germany	2
RTECS	QD7350000
Reaxy-Rn	104378

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Hao Zhang, Duxia Cao, Xiao Cheng, Ruifang Guan, Chuanjian Zhou. (2022) Amide salt pyrolysis fabrication of graphene nanosheets with multi-excitation single color emission. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 627 (671). [PMID:35878459] [10.1016/j.jcis.2022.07.009]
2. Aihong Yang, Wenjing Liu, Xiangyu Li, Wanru Wu, Xiaodi Kou, Rui Shen. (2022) Study on the novel usnic acid derivatives: Design, synthesis, X-Ray crystal structure of Cu(II) complex and anti-AD activities. JOURNAL OF MOLECULAR STRUCTURE, 1263 (133018). [PMID:] [10.1016/j.molstruc.2022.133018]
3. Feixiang Gong, Zhitao Fan, Wenke Xia, Meng Zhang, Lei Wang, Xudong Wang, Xinbing Chen. (2021) N-cyclic cationic group-functionalized cardo poly(arylene ether sulfone)s membranes with ultrahigh selectivity for diffusion dialysis in acid recovery. JOURNAL OF MEMBRANE SCIENCE, 624 (119115). [PMID:] [10.1016/j.memsci.2021.119115]
4. Shuchen Shi, Dongyi Li, Chunxiao Chai, Yufeng Wu, Ying Xu. (2018) Synthesis of a polyaspartic acid/4-(2-aminoethyl) morpholine graft copolymer and evaluation of its scale and corrosion inhibition performance. POLYMERS FOR ADVANCED TECHNOLOGIES, 29 (11): (2838-2847). [PMID:] [10.1002/pat.4406]
5. Zhichao Liu, Shengnan Wang, Wanying Li, Yang Tian. (2018) Bioimaging and Biosensing of Ferrous Ion in Neurons and HepG2 Cells upon Oxidative Stress. ANALYTICAL CHEMISTRY, 90 (4): (2816–2825). [PMID:29376642] [10.1021/acs.analchem.7b04934]
6. Fengyin Liu, Zijian Chen, Yudong Shen, Yuanming Sun, Jinyi Yang, Hong Wang, Hongtao Lei, Zhenlin Xu. (2018) Hapten synthesis and production of specific antibody against 3-amino-5-morpholinomethyl-2-oxazolidone for immunoassay without derivatisation. FOOD AND AGRICULTURAL IMMUNOLOGY, [PMID:] [10.1080/09540105.2017.1376038]
7. Xiaolong Wu, Liling Ma, Shan Sun, Kai Jiang, Ling Zhang, Yuhui Wang, Haibo Zeng, Hengwei Lin. (2018) A versatile platform for the highly efficient preparation of graphene quantum dots: photoluminescence emission and hydrophilicity–hydrophobicity regulation and organelle imaging. Nanoscale, 10 (3): (1532-1539). [PMID:29303204] [10.1039/C7NR08093J]

References

1. Seppo Parkkila,Daniela Vullo,Luca Puccetti,Anna-Kaisa Parkkila,Andrea Scozzafava,Claudiu T Supuran. (2006-05-30) Carbonic anhydrase activators: activation of isozyme XIII with amino acids and amines.. Bioorganic & medicinal chemistry letters, 16 ((15)): (3955-3959). [PMID:16730978]
2. Daniela Vullo,Isao Nishimori,Alessio Innocenti,Andrea Scozzafava,Claudiu T Supuran. (2006-12-19) Carbonic anhydrase activators: an activation study of the human mitochondrial isoforms VA and VB with amino acids and amines.. Bioorganic & medicinal chemistry letters, 17 ((5)): (1336-1340). [PMID:17174092]
3. Isao Nishimori,Saburo Onishi,Daniela Vullo,Alessio Innocenti,Andrea Scozzafava,Claudiu T Supuran. (2007-05-15) Carbonic anhydrase activators: the first activation study of the human secretory isoform VI with amino acids and amines.. Bioorganic & medicinal chemistry, 15 ((15)): (5351-5357). [PMID:17499996]
4. Daniela Vullo,Alessio Innocenti,Isao Nishimori,Andrea Scozzafava,Kai Kaila,Claudiu T Supuran. (2007-06-02) Carbonic anhydrase activators: activation of the human isoforms VII (cytosolic) and XIV (transmembrane) with amino acids and amines.. Bioorganic & medicinal chemistry letters, 17 ((15)): (4107-4112). [PMID:17540561]
5. Silvia Pastorekova,Daniela Vullo,Isao Nishimori,Andrea Scozzafava,Jaromir Pastorek,Claudiu T Supuran. (2008-02-26) Carbonic anhydrase activators: activation of the human tumor-associated isozymes IX and XII with amino acids and amines.. Bioorganic & medicinal chemistry, 16 ((7)): (3530-3536). [PMID:18294854]
6. Daniela Vullo,Isao Nishimori,Andrea Scozzafava,Claudiu T Supuran. (2008-07-17) Carbonic anhydrase activators: Activation of the human cytosolic isozyme III and membrane-associated isoform IV with amino acids and amines.. Bioorganic & medicinal chemistry letters, 18 ((15)): (4303-4307). [PMID:18627905]
7. Alessio Innocenti,Sabrina A Zimmerman,Andrea Scozzafava,James G Ferry,Claudiu T Supuran. (2008-10-22) Carbonic anhydrase activators: activation of the archaeal beta-class (Cab) and gamma-class (Cam) carbonic anhydrases with amino acids and amines.. Bioorganic & medicinal chemistry letters, 18 ((23)): (6194-6198). [PMID:18930395]
8. Semra Isik,Feray Kockar,Meltem Aydin,Oktay Arslan,Ozen Ozensoy Guler,Alessio Innocenti,Andrea Scozzafava,Claudiu T Supuran. (2009-02-24) Carbonic anhydrase activators: activation of the beta-carbonic anhydrase Nce103 from the yeast Saccharomyces cerevisiae with amines and amino acids.. Bioorganic & medicinal chemistry letters, 19 ((6)): (1662-1665). [PMID:19231177]
9. Alessio Innocenti,Mika Hilvo,Seppo Parkkila,Andrea Scozzafava,Claudiu T Supuran. (2009-05-26) Carbonic anhydrase activators. Activation of the membrane-associated isoform XV with amino acids and amines.. Bioorganic & medicinal chemistry letters, 19 ((13)): (3430-3433). [PMID:19464888]
10. Alessio Innocenti,Rebecca A Hall,Andrea Scozzafava,Fritz A Mühlschlegel,Claudiu T Supuran. (2010-01-12) Carbonic anhydrase activators: activation of the beta-carbonic anhydrases from the pathogenic fungi Candida albicans and Cryptococcus neoformans with amines and amino acids.. Bioorganic & medicinal chemistry, 18 ((3)): (1034-1037). [PMID:20061162]
11. Alessio Innocenti,Worraanong Leewattanapasuk,Gheorghe Manole,Andrea Scozzafava,Fritz A Mühlschlegel,Claudiu T Supuran. (2010-02-05) Carbonic anhydrase activators: Activation of the beta-carbonic anhydrase from the pathogenic yeast Candida glabrata with amines and amino acids.. Bioorganic & medicinal chemistry letters, 20 ((5)): (1701-1704). [PMID:20129782]
12. Anthony Bertucci,Didier Zoccola,Sylvie Tambutté,Daniela Vullo,Claudiu T Supuran. (2010-02-24) Carbonic anhydrase activators. The first activation study of a coral secretory isoform with amino acids and amines.. Bioorganic & medicinal chemistry, 18 ((6)): (2300-2303). [PMID:20176489]
13. Arup Podder,Susan M Alex,Mrinmoy Maiti,Kaustabh Kumar Maiti,Sankarprasad Bhuniya. (2017-11-08) Self-calibrated fluorescent probe resembled as an indicator of the lysosomal phosphatase pertaining to the cancer cells.. Journal of photochemistry and photobiology. B, Biology, 177 (105-111). [PMID:29111484]
14. Abdelsattar M Omar,Tamer M Abdelghany,Mohamed S Abdel-Bakky,Abdulrahman M Alahdal,Mohamed F Radwan,Moustafa E El-Araby. (2018-07-27) Design, Synthesis and Antiproliferative Activities of Oxidative Stress Inducers Based on 2-Styryl-3,5-dihydro-4H-imidazol-4-one Scaffold.. Chemical & pharmaceutical bulletin, 66 ((10)): (967-975). [PMID:30047515]
15. Danford Mhule,Rahul S Kalhapure,Mahantesh Jadhav,Calvin A Omolo,Sanjeev Rambharose,Chunderika Mocktar,Sanil Singh,Ayman Y Waddad,Valence M K Ndesendo,Thirumala Govender. (2018-08-21) Synthesis of an oleic acid based pH-responsive lipid and its application in nanodelivery of vancomycin.. International journal of pharmaceutics, 550 ((1-2)): (149-159). [PMID:30125652]
16. Małgorzata Góra, Anna Czopek, Anna Rapacz, Anna Dziubina, Monika Głuch-Lutwin, Barbara Mordyl, Jolanta Obniska. (2020-08-17) Synthesis, Anticonvulsant and Antinociceptive Activity of New Hybrid Compounds: Derivatives of 3-(3-Methylthiophen-2-yl)-pyrrolidine-2,5-dione.. International journal of molecular sciences, 21 ((16)): [PMID:32796594]
17. Apurva Goel,Nisha Tomer,Vikas D Ghule,Rajesh Malhotra. (2020-12-02) A multi-responsive pyranone based Schiff base for the selective, sensitive and competent recognition of copper metal ions.. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 249 (119221-119221). [PMID:33257246]
18. Hao Zhang, Duxia Cao, Xiao Cheng, Ruifang Guan, Chuanjian Zhou. (2022) Amide salt pyrolysis fabrication of graphene nanosheets with multi-excitation single color emission. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 627 (671). [PMID:35878459] [10.1016/j.jcis.2022.07.009]
19. Aihong Yang, Wenjing Liu, Xiangyu Li, Wanru Wu, Xiaodi Kou, Rui Shen. (2022) Study on the novel usnic acid derivatives: Design, synthesis, X-Ray crystal structure of Cu(II) complex and anti-AD activities. JOURNAL OF MOLECULAR STRUCTURE, 1263 (133018). [PMID:] [10.1016/j.molstruc.2022.133018]
20. Feixiang Gong, Zhitao Fan, Wenke Xia, Meng Zhang, Lei Wang, Xudong Wang, Xinbing Chen. (2021) N-cyclic cationic group-functionalized cardo poly(arylene ether sulfone)s membranes with ultrahigh selectivity for diffusion dialysis in acid recovery. JOURNAL OF MEMBRANE SCIENCE, 624 (119115). [PMID:] [10.1016/j.memsci.2021.119115]
21. Shuchen Shi, Dongyi Li, Chunxiao Chai, Yufeng Wu, Ying Xu. (2018) Synthesis of a polyaspartic acid/4-(2-aminoethyl) morpholine graft copolymer and evaluation of its scale and corrosion inhibition performance. POLYMERS FOR ADVANCED TECHNOLOGIES, 29 (11): (2838-2847). [PMID:] [10.1002/pat.4406]
22. Zhichao Liu, Shengnan Wang, Wanying Li, Yang Tian. (2018) Bioimaging and Biosensing of Ferrous Ion in Neurons and HepG2 Cells upon Oxidative Stress. ANALYTICAL CHEMISTRY, 90 (4): (2816–2825). [PMID:29376642] [10.1021/acs.analchem.7b04934]
23. Fengyin Liu, Zijian Chen, Yudong Shen, Yuanming Sun, Jinyi Yang, Hong Wang, Hongtao Lei, Zhenlin Xu. (2018) Hapten synthesis and production of specific antibody against 3-amino-5-morpholinomethyl-2-oxazolidone for immunoassay without derivatisation. FOOD AND AGRICULTURAL IMMUNOLOGY, [PMID:] [10.1080/09540105.2017.1376038]
24. Xiaolong Wu, Liling Ma, Shan Sun, Kai Jiang, Ling Zhang, Yuhui Wang, Haibo Zeng, Hengwei Lin. (2018) A versatile platform for the highly efficient preparation of graphene quantum dots: photoluminescence emission and hydrophilicity–hydrophobicity regulation and organelle imaging. Nanoscale, 10 (3): (1532-1539). [PMID:29303204] [10.1039/C7NR08093J]

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