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4,4'-Dihydroxydiphenyl - 99.0%, high purity , CAS No.92-88-6

71 Citations
  • ≥99%
Item Number
D400225
Grouped product items
SKUSizeAvailabilityPrice Qty
D400225-25g
25g
In stock
$68.90
D400225-100g
100g
In stock
$181.90
D400225-500g
500g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$446.90
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Basic Description

Synonymspara,para'-Biphenol | p-Dihydroxydiphenyl | AC-7327 | NCGC00248640-02 | p,p''-biphenol | p,p'-Biphenol | 1,1'-biphenyl-4,4'-diol | 4HB | biphenyl-4,4''-diol | Biphenyl-4,4'-diol | STK365601 | p,p''-dihydroxybiphenyl | p,p'-Dihydroxybiphenyl | EC 202-200-5
Specifications & Purity≥99%
Storage TempProtected from light
Shipped InNormal
Product Description

4,4'-Dihydroxybiphenyl is used to prepare plastics. It serves as a laboratory reagent and an intermediate in the preparation of polyether liquid crystals. Further, it is used as an antioxidant agent for rubber and latex. In addition to this, it is used in light-colored rubber products, food packaging and medical latex products.

Associated Targets(Human)

ESR2 Tclin Estrogen receptor beta (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
UGT2B15 Tbio UDP-glucuronosyltransferase 2B15 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
UGT1A1 Tchem UDP-glucuronosyltransferase 1-1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
UGT1A4 Tbio UDP-glucuronosyltransferase 1-4 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
KRAS Tclin GTPase KRas (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
RHEB Tbio GTP-binding protein Rheb (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
NT5C2 Tbio Cytosolic purine 5'-nucleotidase (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
IDO1 Tchem Indoleamine 2,3-dioxygenase 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
MMP3 Tchem Stromelysin-1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
MMP3 Tchem Matrix metalloproteinase 3 (3433 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UGT1A4 Tbio UDP-glucuronosyltransferase 1A4 (288 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HT-29 (80576 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MCF7 (126967 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HEK293 (82097 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HeLa (62764 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
IDO1 Tchem Indoleamine 2,3-dioxygenase (6650 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UGT2B15 Tbio UDP-glucuronosyltransferase 2B15 (172 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UGT1A1 Tchem UDP-glucuronosyltransferase 1-1 (448 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KRAS Tclin GTPase KRas (1864 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RHEB Tbio GTP-binding protein Rheb (5 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

COS-7 (515 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ESR1 Estrogen receptor (4 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 4-(4-hydroxyphenyl)phenol
INCHI InChI=1S/C12H10O2/c13-11-5-1-9(2-6-11)10-3-7-12(14)8-4-10/h1-8,13-14H
InChi Key VCCBEIPGXKNHFW-UHFFFAOYSA-N
Canonical SMILES C1=CC(=CC=C1C2=CC=C(C=C2)O)O
Isomeric SMILES C1=CC(=CC=C1C2=CC=C(C=C2)O)O
WGK Germany 2
RTECS DV4725000
PubChem CID 7112
UN Number 3088
Packing Group III
Molecular Weight 186.21
Beilstein 1908886
Reaxy-Rn 1908886

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

19 results found

Lot NumberCertificate TypeDateItem
F2419157Certificate of AnalysisMar 21, 2024 D400225
D2425198Certificate of AnalysisMar 21, 2024 D400225
G2411068Certificate of AnalysisApr 19, 2023 D400225
E2329088Certificate of AnalysisApr 19, 2023 D400225
E2329090Certificate of AnalysisApr 19, 2023 D400225
E2329092Certificate of AnalysisApr 19, 2023 D400225
E2329095Certificate of AnalysisApr 19, 2023 D400225
E2329096Certificate of AnalysisApr 19, 2023 D400225
E2329099Certificate of AnalysisApr 19, 2023 D400225
K2224427Certificate of AnalysisNov 01, 2022 D400225
K2224414Certificate of AnalysisNov 01, 2022 D400225
K2224410Certificate of AnalysisNov 01, 2022 D400225
K2224409Certificate of AnalysisNov 01, 2022 D400225
B2308116Certificate of AnalysisNov 01, 2022 D400225
B2308117Certificate of AnalysisJan 17, 2022 D400225
B2218473Certificate of AnalysisJan 17, 2022 D400225
B2218468Certificate of AnalysisJan 17, 2022 D400225
B2218453Certificate of AnalysisJan 17, 2022 D400225
B2218386Certificate of AnalysisJan 17, 2022 D400225

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Chemical and Physical Properties

SolubilitySlightly soluble in water.
Sensitivitylight sensitive
Melt Point(°C)278-283°C

Safety and Hazards(GHS)

Pictogram(s) GHS09,   GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H411:Toxic to aquatic life with long lasting effects

H412:Harmful to aquatic life with long lasting effects

H317:May cause an allergic skin reaction

H312:Harmful in contact with skin

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P273:Avoid release to the environment.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P272:Contaminated work clothing should not be allowed out of the workplace.

P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention.

P362+P364:Take off contaminated clothing and wash it before reuse.

P391:Collect spillage.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P317:Get emergency medical help.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 2
RTECS DV4725000
Reaxy-Rn 1908886
Class 4.2

Related Documents

 SDS

 Specification Sheet

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Citations of This Product

How to Cite Aladdin Scientific Products?
1. Weiping Xu, Guochen Wang, Dong Chen, Wantai Yang, Yuhong Ma.  (2023)  Synchronously Improving Mechanical and Thermal Performances of Cured Epoxy Resins by Epoxidized Polyether Sulphones as Modifiers.  MACROMOLECULAR CHEMISTRY AND PHYSICS,    (17): (2300351).  [PMID:12444095] [10.1002/macp.202300351]
2. Lan Luo, Fenghua Zhang, Linlin Wang, Yanju Liu, Jinsong Leng.  (2023)  Multidimensional cross-linked network strategies for Rapidly, Reconfigurable, refoldable shape memory polymer.  CHEMICAL ENGINEERING JOURNAL,  478  (14): (147428).  [PMID:20228063] [10.1016/j.cej.2023.147428]
3. Huagao Fang, Fan Zhang, Yongpu Zhao, Xingchen Gao, Wenjuan Zhou, Guobin Qi, Yunsheng Ding, H. Henning Winter.  (2023)  Rheology of Smectic Liquid Crystalline Elastomers with Dynamic Covalent Bonds.  MACROMOLECULES,  56  (19): (7808–7817).  [PMID:29691401] [10.1021/acs.macromol.3c00887]
4. Zichun Ding, Lishuai Zong, Chenghao Wang, Siying Wang, RunZe Liu, Xigao Jian, Jinyan Wang.  (2023)  A new approach to enhance the performance of phthalonitrile: study of carborane curing agents with dual functions.  Molecular Systems Design & Engineering,  8  (12): (1492-1497).  [PMID:] [10.1039/D3ME00103B]
5. Chenchen Zhang, Huanping Wu, Shunan Feng, Jianqiang Meng.  (2023)  Fluorination as a powerful tool for improving water/salt selectivity of hydrophilic polyethersulfone.  JOURNAL OF MEMBRANE SCIENCE,  687  (122030).  [PMID:] [10.1016/j.memsci.2023.122030]
6. Yifei Wu, Kun Wu, Fei Xiao, Wenjie Diao, Daguang He, Hui Yang, Jun Shi.  (2023)  High Thermal Conductivity and Low Dielectric Constant of Polyesters Based on Fluorine and Mesogenic Unit.  MACROMOLECULAR CHEMISTRY AND PHYSICS,  224  (19): (2300078).  [PMID:] [10.1002/macp.202300078]
7. Ying Li, Yi Wu, Xiaoxiao Huang, Changdan Gong, Qin Shi, Wenying Zhou, Qiwei Cheng.  (2023)  Flexible and thermally conductive epoxy-dispersed liquid crystal composites filled with functionalized boron nitride nanosheets.  POLYMER COMPOSITES,  44  (10): (6581-6592).  [PMID:] [10.1002/pc.27581]
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13. Jiafeng Qian, Shiju Cai, Jianxiong Hu, Chenyi Wang, Guang Li.  (2023)  Preparation and Properties of Quaternary Ammonium Anion Exchange Membranes with Flexible Side Chains for the Vanadium Redox Flow Battery.  INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH,  62  (6): (2719–2728).  [PMID:] [10.1021/acs.iecr.2c04081]
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15. Xiankun Wu, Jiale Zhang, Haonan Li, Huihui Gao, Mang Wu, Zhongkai Wang, Zhong Wang.  (2023)  Dual-hard phase structures make mechanically tough and autonomous self-healable polyurethane elastomers.  CHEMICAL ENGINEERING JOURNAL,  454  (140268).  [PMID:] [10.1016/j.cej.2022.140268]
16. Sheng Jie Yuan, Zhong Quan Peng, Min Zhi Rong, Ming Qiu Zhang.  (2022)  Increasing strengths of liquid crystalline polymers while minimizing anisotropy via topological rearrangement assisted bi-directional stretching of reversibly interlocked macromolecular networks.  Applied Materials Today,  29  (101643).  [PMID:] [10.1016/j.apmt.2022.101643]
17. Shengda Wang, Hanqing Jiang, Ronghua Yu, Shenghui Lou, Li Ma, Jie Liu, Tao Tang.  (2022)  Synthesis and Flame-Retardant Performance of Epoxy Resins Containing Aromatic Imine from Different Bisphenols Based on the Duff Reaction.  CHEMISTRY OF MATERIALS,  34  (19): (8629–8640).  [PMID:] [10.1021/acs.chemmater.2c01590]
18. Yao Ma, Jinfan Chen, Xiaodong Du, Chunsheng Xie, Jiangmin Zhou, Xueqin Tao, Zhi Dang, Guining Lu.  (2023)  Efficient removal of polybrominated diphenyl ethers from soil washing effluent by dummy molecular imprinted adsorbents: Selectivity and mechanisms.  Journal of Environmental Sciences,  129  (45).  [PMID:36804241] [10.1016/j.jes.2022.08.026]
19. Shenghua Du, Shuai Huang, Ning Xie, Tong Zhang, Yaoyao Xu, Xingming Ning, Pei Chen, Xinbing Chen, Zhongwei An.  (2022)  New block poly(ether sulfone) based anion exchange membranes with rigid side-chains and high-density quaternary ammonium groups for fuel cell application.  Polymer Chemistry,  13  (30): (4395-4405).  [PMID:] [10.1039/D2PY00588C]
20. Yan Xiao, Junhui Xu, Lei Hu, Hui Wang, Li Gao, Shiqi Peng, Mengting Di, Xiaojun Sun, Jie Liu, Xiaoming Yan, Liuping Chen, Gaohong He.  (2022)  Advanced anion-selective membranes with pendant quaternary ammonium for neutral aqueous supporting redox flow battery.  JOURNAL OF MEMBRANE SCIENCE,  659  (120748).  [PMID:] [10.1016/j.memsci.2022.120748]
21. Xiaole Zheng, Yingjie Zhan, Yingchun Liu, Maoping Lu, Enxiang Jiao, Hangzhen Zhang, Jun Shi, Mangeng Lu, Kun Wu.  (2022)  High intrinsic thermally conductivity side-chain liquid crystalline polysiloxane films grafted with pendent difunctional mesogenic groups.  Polymer Chemistry,  13  (26): (3915-3929).  [PMID:] [10.1039/D2PY00432A]
22. Caifen Chen, Dan Li, Baokang Jin.  (2022)  Development of a Selective Electrochemical Biosensor for Bisphenol a Based on Target-Induced Chain Release Involving Methylene Blue Release.  ANALYTICAL LETTERS,      [PMID:] [10.1080/00032719.2022.2026374]
23. Shenghua Du, Songsong Li, Ning Xie, Yaoyao Xu, Qiang Weng, Xingming Ning, Pei Chen, Xinbing Chen, Zhongwei An.  (2022)  Development of rigid side-chain poly(ether sulfone)s based anion exchange membrane with multiple annular quaternary ammonium ion groups for fuel cells.  POLYMER,  251  (124919).  [PMID:] [10.1016/j.polymer.2022.124919]
24. Zui Liu, Guangqiang Guo, Junqiu Liao, Yongjie Yuan, Hailiang Zhang.  (2022)  Manipulated and Improved Photoinduced Deformation Property of Photoresponsive Liquid Crystal Elastomers by Copolymerization.  MACROMOLECULAR RAPID COMMUNICATIONS,  43  (6): (2100717).  [PMID:35083802] [10.1002/marc.202100717]
25. Feng Zhiqiang, Liu Xiaohong, Zhang Wenchao, Zeng Juanjuan, Liu Jiaming, Chen Bifang, Lin Jiaming, Tan Liqin, Liang Liyan.  (2022)  Functionalized mesoporous silica liquid crystal epoxy resin composite: an ideal low-dielectric hydrophobic material.  JOURNAL OF MATERIALS SCIENCE,  57  (2): (1156-1173).  [PMID:] [10.1007/s10853-021-06672-w]
26. Junyu Chu, Heng Wang, Yiwen Zhang, Zhengkai Li, Zhencai Zhang, Hongyan He, Qinqin Zhang, Fei Xu.  (2022)  Design and synthesis of gradient-refractive index isosorbide-based polycarbonates for optical uses.  REACTIVE & FUNCTIONAL POLYMERS,  170  (105145).  [PMID:] [10.1016/j.reactfunctpolym.2021.105145]
27. Jiajun Yu, Bingbing Luo, Yihan Wang, Siyu Wang, Kai Wu, Chao Liu, Sheng Chu, Huiyan Zhang.  (2022)  An efficient way to synthesize biomass-based molybdenum carbide catalyst via pyrolysis carbonization and its application for lignin catalytic pyrolysis.  BIORESOURCE TECHNOLOGY,  346  (126640).  [PMID:34971778] [10.1016/j.biortech.2021.126640]
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34. Fugang He, Shouping Wang, Diao Yuan, Qiang Weng, Pei Chen, Xinbing Chen, Zhongwei An.  (2020)  Crosslinked poly(arylene ether sulfone) block copolymers containing quinoxaline crosslinkage and pendant butanesulfonic acid groups as proton exchange membranes.  INTERNATIONAL JOURNAL OF HYDROGEN ENERGY,  45  (25262).  [PMID:] [10.1016/j.ijhydene.2020.06.149]
35. Yanfu Tang, Li Yuan, Guozheng Liang, Aijuan Gu.  (2020)  Reprocessable Triple-Shape-Memory Liquid Crystalline Polyester Amide with Ultrahigh Thermal Resistance.  INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH,  59  (31): (14015–14024).  [PMID:] [10.1021/acs.iecr.0c02045]
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38. Dan Ren, Yu-Tao Jin, Tian-Yin Liu, Xiaolin Wang.  (2020)  Phenanthroline-Based Polyarylate Porous Membranes with Rapid Water Transport for Metal Cation Separation.  ACS Applied Materials & Interfaces,  12  (6): (7605–7616).  [PMID:31968159] [10.1021/acsami.9b22086]
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40. Mengjie Tian, Kai Yu, Leyan Li, Yafei Wang, Liping Guo, Zulei Zhang, Yixia Lu, Lei Li.  (2019)  Fabrication of dual-template molecularly imprinted mesoporous silica for simultaneous rapid and efficient detection of bisphenol A and diethylstilbestrol in environmental water samples.  Analytical Methods,  11  (37): (4761-4768).  [PMID:] [10.1039/C9AY01368G]
41. Wen Qijuan, Sun Tanghao, Wang Qi, Huang Wenwen, Liu Yunchun.  (2019)  Unique thiophilic affinity MOFs as specific sorbent for disulfide bond-containing compounds capture.  SN Applied Sciences,  1  (7): (1-8).  [PMID:] [10.1007/s42452-019-0799-3]
42. Shengwen Kong, Xiaodong Wang, Lu Bai, Ying Song, Fanbao Meng.  (2019)  Multi-arm ionic liquid crystals formed by pyridine-mesophase and copper phthalocyanine.  JOURNAL OF MOLECULAR LIQUIDS,  288  (111012).  [PMID:] [10.1016/j.molliq.2019.111012]
43. Xiaodong Huang, Zhen Zhang, Xiang-Yu Kong, Yue Sun, Congcong Zhu, Pei Liu, Jinhui Pang, Lei Jiang, Liping Wen.  (2019)  Engineered PES/SPES nanochannel membrane for salinity gradient power generation.  Nano Energy,  59  (354).  [PMID:] [10.1016/j.nanoen.2019.02.056]
44. Peng Wei, Yanping Wang, Yumin Xia, Yong He, Yimin Wang.  (2019)  Synthesis and properties of novel photocrosslinkable aromatic-aliphatic liquid crystal copolyesters based on poly(ethylene glycol) and cinnamic acid.  LIQUID CRYSTALS,      [PMID:] [10.1080/02678292.2018.1482507]
45. Yafei Wang, Mengjie Tian, Kai Yu, Leyan Li, Zulei Zhang, Lei Li.  (2019)  A versatile strategy to fabricate magnetic dummy molecularly imprinted mesoporous silica particles for specific magnetic separation of bisphenol A.  NEW JOURNAL OF CHEMISTRY,  43  (8): (3400-3408).  [PMID:] [10.1039/C8NJ06027D]
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