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Synonyms | 4,4'-Methylenediphenol | 620-92-8 | 4,4'-Dihydroxydiphenylmethane | Bisphenol F | Bis(4-hydroxyphenyl)methane | Phenol, 4,4'-methylenebis- | p-(p-Hydroxybenzyl)phenol | 4,4'-Methylenebisphenol | Phenol, 4,4'-methylenedi- | BIS(P-HYDROXYPHENYL)METHANE | 4-[(4-hydroxyphenyl)me |
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Specifications & Purity | ≥99%(GC) |
Shipped In | Normal |
Product Description | 4,4'-Dihydroxydiphenylmethane, is also used as a bisphenol derivative with antioxidant activities. Bisphenol F has been reported to exhibit estrogen agonistic properties. Bisphenol F is used to make epoxy resins and coatings for various applications, such as lacquers, varnishes, liners, adhesives, plastics, water pipes, dental sealants, and food packaging. |
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Pubchem Sid | 488181550 |
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Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488181550 |
IUPAC Name | 4-[(4-hydroxyphenyl)methyl]phenol |
INCHI | InChI=1S/C13H12O2/c14-12-5-1-10(2-6-12)9-11-3-7-13(15)8-4-11/h1-8,14-15H,9H2 |
InChi Key | PXKLMJQFEQBVLD-UHFFFAOYSA-N |
Canonical SMILES | C1=CC(=CC=C1CC2=CC=C(C=C2)O)O |
Isomeric SMILES | C1=CC(=CC=C1CC2=CC=C(C=C2)O)O |
WGK Germany | 2 |
RTECS | SL9625000 |
PubChem CID | 12111 |
Molecular Weight | 200.24 |
Beilstein | 6995 |
Reaxy-Rn | 2049425 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
F2427502 | Certificate of Analysis | Jul 05, 2024 | D135041 |
F2427511 | Certificate of Analysis | Jul 05, 2024 | D135041 |
A2417305 | Certificate of Analysis | Jan 26, 2024 | D135041 |
A2417306 | Certificate of Analysis | Jan 26, 2024 | D135041 |
A2417307 | Certificate of Analysis | Jan 26, 2024 | D135041 |
H2322337 | Certificate of Analysis | Aug 29, 2023 | D135041 |
H2322338 | Certificate of Analysis | Aug 29, 2023 | D135041 |
H2322350 | Certificate of Analysis | Aug 29, 2023 | D135041 |
F2325421 | Certificate of Analysis | Oct 20, 2022 | D135041 |
F2325424 | Certificate of Analysis | Oct 20, 2022 | D135041 |
F2325439 | Certificate of Analysis | Oct 20, 2022 | D135041 |
J2217429 | Certificate of Analysis | Oct 20, 2022 | D135041 |
J2217430 | Certificate of Analysis | Oct 20, 2022 | D135041 |
J2217431 | Certificate of Analysis | Oct 20, 2022 | D135041 |
J2217433 | Certificate of Analysis | Oct 20, 2022 | D135041 |
Solubility | It is soluble in ethanol, ether, chloroform, alkali; slightly soluble in DMSO, insoluble in carbon disulfide and water. |
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Melt Point(°C) | 159-163°C |
Pictogram(s) | GHS09, GHS05, GHS07 |
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Signal | Danger |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H411:Toxic to aquatic life with long lasting effects H412:Harmful to aquatic life with long lasting effects H318:Causes serious eye damage H317:May cause an allergic skin reaction |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P391:Collect spillage. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. P317:Get emergency medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
WGK Germany | 2 |
RTECS | SL9625000 |
Reaxy-Rn | 2049425 |
1. Jilei Xu, Ping Chen, Shuaijiang Ma, Guohao Zhu. (2024) Synthesis and properties of novel bismaleimide containing allyl group and twisted structure. THERMOCHIMICA ACTA, 732 (179661). [PMID:] |
2. Xiaolan Zhang, Shufang Xu, Zhimin Liu, Zhigang Xu, Qinpeng Shen, Shiyun Tang, Zhihua Liu, Xiaoxi Si. (2024) Flexible molecularly imprinted fiber library for the metabolic analysis of bisphenol F and ecological risk evaluation. JOURNAL OF HAZARDOUS MATERIALS, 465 (133300). [PMID:38141296] |
3. Xianheng Li, Huan Li, Keqiang Lai, Junjian Miao, Jie Zhao. (2024) New natural deep eutectic solvent for vortex-assisted liquid–liquid microextraction for the determination of bisphenols in beverages. MICROCHEMICAL JOURNAL, 197 (18): (109710). [PMID:26382858] |
4. Xianheng Li, Huan Li, Keqiang Lai, Jie Zhao, Junjian Miao. (2024) A novel deep eutectic solvent as an extractant for the determination of bisphenol compounds in edible oils by high-performance liquid-phase fluorescence detection. JOURNAL OF FOOD COMPOSITION AND ANALYSIS, 126 (105864). [PMID:24005054] |
5. Longyu Tian, Min Wang, Guangming Liao, Baoliang Liu, Sujuan Zhang, Yucheng Sun, Zhen Meng, Jintao Zhang, Zaijun Lu. (2024) High performance quaternary ammonium-functionalized polybenzoxazine-based anion exchange membranes. POLYMER, 290 (20): (126520). [PMID:25457612] |
6. Min Jia, Fupei Xu, Fei Zhai, Xiaoying Yu, Meixia Du. (2023) An all-in-one portable colorimetric detection platform for sensitive detection of bisphenol A based on target-mediated CeO2@ZIF-8/Apt biocomposites. JOURNAL OF COLLOID AND INTERFACE SCIENCE, (10): [PMID:37845127] |
7. Siqi Wu, Siyao Liu, Zhiming Wang, Yinguang Chen, Guohua Zhao. (2023) Comprehensive analysis of bisphenol analogues in complex water using a group-targeting aptamer engineered by base mutation. JOURNAL OF HAZARDOUS MATERIALS, 460 (18): (132427). [PMID:37672991] |
8. Pengjia Sun, Ping Sun, Yingsen Fang, Hui Liu, Bitao Xiong, Hui Wang, Xingao Li. (2023) Enhanced degradation of bisphenol S in water using a combination process of electrochemical oxidation with periodate activation. Journal of Water Process Engineering, 55 (104203). [PMID:] |
9. Yuting Zhang, Lin Hao, Jie Li, Weihua Liu, Zhi Wang, Qiuhua Wu, Chun Wang. (2023) Synthesis of amine-functionalized magnetic porous organic polymers for effective extraction of phenolic endocrine disrupting chemicals. JOURNAL OF CHROMATOGRAPHY A, 1706 (464271). [PMID:37544235] |
10. Zhiying Liang, Yafen Guo, Duan Pi, Xiang Li, Bingying Li, Yongsi Huang, Xiaohong Song, Ramji Kumar Bhandari, Xuegeng Wang. (2023) Transcriptome Analysis of the Developmental Effects of Bisphenol F Exposure in Chinese Medaka (Oryzias sinensis). INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24 (13): (10898). [PMID:37446079] |
11. Sun Hao-Fei, Cui Yuan-Yuan, Li Hong-Liang, Yang Cheng-Xiong. (2023) Click postsynthesis of microporous organic network@silica composites for reversed-phase/hydrophilic interaction mixed-mode chromatography. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 415 (18): (4533-4543). [PMID:37017725] |
12. Jiamei Liu, Weichen Sheng, Rui Yang, Yu Liu, Yin Lu, Kan Zhang. (2022) Synthesis of bio-diamine derived main-chain type benzoxazine resins with low surface free energy. JOURNAL OF APPLIED POLYMER SCIENCE, 140 (10): (e53578). [PMID:] |
13. Xiqing Liu, Tao Wang, Yongqing Wang. (2023) Selective and ratiometric fluorescence sensing of bisphenol A in canned food based on portable fluorescent test strips. ANALYTICA CHIMICA ACTA, 1240 (340728). [PMID:36641151] |
14. Linli Dai, Yi Xie, Yongkui Zhang, Yabo Wang. (2023) Fe2P/N-doped biocarbon composite derived from mycelial pellet for bisphenol AF removal through peroxymonosulfate activation. Journal of Environmental Chemical Engineering, 11 (109130). [PMID:] |
15. Yue Zhao, Chenghong Feng, Chenhao Tian, Zhenling Li, Yu Yang. (2022) Enhanced adsorption selectivity of bisphenol analogues by tuning the functional groups of covalent organic frameworks (COFs). SEPARATION AND PURIFICATION TECHNOLOGY, 297 (121489). [PMID:] |
16. Yang Feng, Min Sun, Mingxia Sun, Jiaqing Feng, Haili Sun, Juanjuan Feng. (2022) Extraction performance-structure relationship of polyamidoamine dendrimers on silica for online solid-phase extraction of organic pollutants. JOURNAL OF CHROMATOGRAPHY A, 1673 (463132). [PMID:35576765] |
17. Li Chen, Tahir Maqbool, Ghazanfar Nazir, Congyu Hou, Yulong Yang, Jianning Guo, Xihui Zhang. (2022) Developing the large-area manganese-based catalytic ceramic membrane for peroxymonosulfate activation: Applications in degradation of endocrine disrupting compounds in drinking water. JOURNAL OF MEMBRANE SCIENCE, 655 (120602). [PMID:] |
18. Lingli Zhang, Han Tao, Chun Ji, Qiaoling Wu, Xiao Wang, Yuangeng Wu. (2022) Sensitive and direct electrochemical detection of bisphenol S based on 1T&2H-MoS2/CNTs-NH2 nanocomposites. NEW JOURNAL OF CHEMISTRY, 46 (17): (8203-8214). [PMID:] |
19. Mengfan Cao, Yanjiao Zou, Yuanyuan Zhang, Ting Zeng, Qijin Wan, Guosong Lai, Nianjun Yang. (2022) Robust and selective electrochemical sensing of hazardous photographic developing agents using a MOF-derived 3D porous flower-like Co3O4@C/graphene nanoplate composite. ELECTROCHIMICA ACTA, 409 (139967). [PMID:] |
20. Zhendong Yu, Jiachen Ma, Xiaoyi Huang, Yuancai Lv, Yifan Liu, Chunxiang Lin, Rongni Dou, Xiaoxia Ye, Yongqian Shi, Minghua Liu. (2022) Insights into enhanced peroxydisulfate activation with S doped Fe@C catalyst for the rapid degradation of organic pollutants. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 610 (24). [PMID:34920214] |
21. Jie Liu, Qian Liu, Liulin Wei, Xiaomei Chen, Zhiqiang Li, Yidong Xu, Xueyun Gao, Xiaoxiao Lu, Jingchan Zhao. (2022) A novel polyhedral oligomeric silsesquioxane-based hybrid monolith as a sorbent for on-line in-tube solid phase microextraction of bisphenols in milk prior to high performance liquid chromatography-ultraviolet detection analysis. FOOD CHEMISTRY, 374 (131775). [PMID:34896942] |
22. Mingxia Sun, Juanjuan Feng, Jiaqing Feng, Haili Sun, Yang Feng, Xiangping Ji, Chunying Li, Sen Han, Min Sun. (2022) Biochar nanosphere- and covalent organic framework nanosphere-functionalized titanium dioxide nanorod arrays on carbon fibers for solid-phase microextraction of organic pollutants. CHEMICAL ENGINEERING JOURNAL, 433 (133645). [PMID:] |
23. Yabo Shi,Min Liu,Hui Yan,Chang Cai,Qingying Guo,Wenxin Pei,Ruiyan Zhang,Zhengping Wang,Jun Han. (2018-09-01) Mutual influence of piceatannol and bisphenol F on their interaction with pepsin: Insights from spectroscopic, isothermal titration calorimetry and molecular modeling studies.. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 206 (384-395). [PMID:30170174] |
24. Na Wei,Zhenjia Zheng,Yuhua Wang,Yanduo Tao,Yun Shao,Shuyun Zhu,Jinmao You,Xian-En Zhao. (2017-04-04) Rapid and sensitive determination of multiple endocrine-disrupting chemicals by ultrasound-assisted in situ derivatization dispersive liquid-liquid microextraction coupled with ultra-high-performance liquid chromatography/tandem mass spectrometry.. Rapid communications in mass spectrometry : RCM, 31 ((11)): (937-950). [PMID:28370680] |
1. Jilei Xu, Ping Chen, Shuaijiang Ma, Guohao Zhu. (2024) Synthesis and properties of novel bismaleimide containing allyl group and twisted structure. THERMOCHIMICA ACTA, 732 (179661). [PMID:] |
2. Xiaolan Zhang, Shufang Xu, Zhimin Liu, Zhigang Xu, Qinpeng Shen, Shiyun Tang, Zhihua Liu, Xiaoxi Si. (2024) Flexible molecularly imprinted fiber library for the metabolic analysis of bisphenol F and ecological risk evaluation. JOURNAL OF HAZARDOUS MATERIALS, 465 (133300). [PMID:38141296] |
3. Xianheng Li, Huan Li, Keqiang Lai, Junjian Miao, Jie Zhao. (2024) New natural deep eutectic solvent for vortex-assisted liquid–liquid microextraction for the determination of bisphenols in beverages. MICROCHEMICAL JOURNAL, 197 (18): (109710). [PMID:26382858] |
4. Xianheng Li, Huan Li, Keqiang Lai, Jie Zhao, Junjian Miao. (2024) A novel deep eutectic solvent as an extractant for the determination of bisphenol compounds in edible oils by high-performance liquid-phase fluorescence detection. JOURNAL OF FOOD COMPOSITION AND ANALYSIS, 126 (105864). [PMID:24005054] |
5. Longyu Tian, Min Wang, Guangming Liao, Baoliang Liu, Sujuan Zhang, Yucheng Sun, Zhen Meng, Jintao Zhang, Zaijun Lu. (2024) High performance quaternary ammonium-functionalized polybenzoxazine-based anion exchange membranes. POLYMER, 290 (20): (126520). [PMID:25457612] |
6. Min Jia, Fupei Xu, Fei Zhai, Xiaoying Yu, Meixia Du. (2023) An all-in-one portable colorimetric detection platform for sensitive detection of bisphenol A based on target-mediated CeO2@ZIF-8/Apt biocomposites. JOURNAL OF COLLOID AND INTERFACE SCIENCE, (10): [PMID:37845127] |
7. Siqi Wu, Siyao Liu, Zhiming Wang, Yinguang Chen, Guohua Zhao. (2023) Comprehensive analysis of bisphenol analogues in complex water using a group-targeting aptamer engineered by base mutation. JOURNAL OF HAZARDOUS MATERIALS, 460 (18): (132427). [PMID:37672991] |
8. Pengjia Sun, Ping Sun, Yingsen Fang, Hui Liu, Bitao Xiong, Hui Wang, Xingao Li. (2023) Enhanced degradation of bisphenol S in water using a combination process of electrochemical oxidation with periodate activation. Journal of Water Process Engineering, 55 (104203). [PMID:] |
9. Yuting Zhang, Lin Hao, Jie Li, Weihua Liu, Zhi Wang, Qiuhua Wu, Chun Wang. (2023) Synthesis of amine-functionalized magnetic porous organic polymers for effective extraction of phenolic endocrine disrupting chemicals. JOURNAL OF CHROMATOGRAPHY A, 1706 (464271). [PMID:37544235] |
10. Zhiying Liang, Yafen Guo, Duan Pi, Xiang Li, Bingying Li, Yongsi Huang, Xiaohong Song, Ramji Kumar Bhandari, Xuegeng Wang. (2023) Transcriptome Analysis of the Developmental Effects of Bisphenol F Exposure in Chinese Medaka (Oryzias sinensis). INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24 (13): (10898). [PMID:37446079] |
11. Sun Hao-Fei, Cui Yuan-Yuan, Li Hong-Liang, Yang Cheng-Xiong. (2023) Click postsynthesis of microporous organic network@silica composites for reversed-phase/hydrophilic interaction mixed-mode chromatography. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 415 (18): (4533-4543). [PMID:37017725] |
12. Jiamei Liu, Weichen Sheng, Rui Yang, Yu Liu, Yin Lu, Kan Zhang. (2022) Synthesis of bio-diamine derived main-chain type benzoxazine resins with low surface free energy. JOURNAL OF APPLIED POLYMER SCIENCE, 140 (10): (e53578). [PMID:] |
13. Xiqing Liu, Tao Wang, Yongqing Wang. (2023) Selective and ratiometric fluorescence sensing of bisphenol A in canned food based on portable fluorescent test strips. ANALYTICA CHIMICA ACTA, 1240 (340728). [PMID:36641151] |
14. Linli Dai, Yi Xie, Yongkui Zhang, Yabo Wang. (2023) Fe2P/N-doped biocarbon composite derived from mycelial pellet for bisphenol AF removal through peroxymonosulfate activation. Journal of Environmental Chemical Engineering, 11 (109130). [PMID:] |
15. Yue Zhao, Chenghong Feng, Chenhao Tian, Zhenling Li, Yu Yang. (2022) Enhanced adsorption selectivity of bisphenol analogues by tuning the functional groups of covalent organic frameworks (COFs). SEPARATION AND PURIFICATION TECHNOLOGY, 297 (121489). [PMID:] |
16. Yang Feng, Min Sun, Mingxia Sun, Jiaqing Feng, Haili Sun, Juanjuan Feng. (2022) Extraction performance-structure relationship of polyamidoamine dendrimers on silica for online solid-phase extraction of organic pollutants. JOURNAL OF CHROMATOGRAPHY A, 1673 (463132). [PMID:35576765] |
17. Li Chen, Tahir Maqbool, Ghazanfar Nazir, Congyu Hou, Yulong Yang, Jianning Guo, Xihui Zhang. (2022) Developing the large-area manganese-based catalytic ceramic membrane for peroxymonosulfate activation: Applications in degradation of endocrine disrupting compounds in drinking water. JOURNAL OF MEMBRANE SCIENCE, 655 (120602). [PMID:] |
18. Lingli Zhang, Han Tao, Chun Ji, Qiaoling Wu, Xiao Wang, Yuangeng Wu. (2022) Sensitive and direct electrochemical detection of bisphenol S based on 1T&2H-MoS2/CNTs-NH2 nanocomposites. NEW JOURNAL OF CHEMISTRY, 46 (17): (8203-8214). [PMID:] |
19. Mengfan Cao, Yanjiao Zou, Yuanyuan Zhang, Ting Zeng, Qijin Wan, Guosong Lai, Nianjun Yang. (2022) Robust and selective electrochemical sensing of hazardous photographic developing agents using a MOF-derived 3D porous flower-like Co3O4@C/graphene nanoplate composite. ELECTROCHIMICA ACTA, 409 (139967). [PMID:] |
20. Zhendong Yu, Jiachen Ma, Xiaoyi Huang, Yuancai Lv, Yifan Liu, Chunxiang Lin, Rongni Dou, Xiaoxia Ye, Yongqian Shi, Minghua Liu. (2022) Insights into enhanced peroxydisulfate activation with S doped Fe@C catalyst for the rapid degradation of organic pollutants. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 610 (24). [PMID:34920214] |
21. Jie Liu, Qian Liu, Liulin Wei, Xiaomei Chen, Zhiqiang Li, Yidong Xu, Xueyun Gao, Xiaoxiao Lu, Jingchan Zhao. (2022) A novel polyhedral oligomeric silsesquioxane-based hybrid monolith as a sorbent for on-line in-tube solid phase microextraction of bisphenols in milk prior to high performance liquid chromatography-ultraviolet detection analysis. FOOD CHEMISTRY, 374 (131775). [PMID:34896942] |
22. Mingxia Sun, Juanjuan Feng, Jiaqing Feng, Haili Sun, Yang Feng, Xiangping Ji, Chunying Li, Sen Han, Min Sun. (2022) Biochar nanosphere- and covalent organic framework nanosphere-functionalized titanium dioxide nanorod arrays on carbon fibers for solid-phase microextraction of organic pollutants. CHEMICAL ENGINEERING JOURNAL, 433 (133645). [PMID:] |
23. Yabo Shi,Min Liu,Hui Yan,Chang Cai,Qingying Guo,Wenxin Pei,Ruiyan Zhang,Zhengping Wang,Jun Han. (2018-09-01) Mutual influence of piceatannol and bisphenol F on their interaction with pepsin: Insights from spectroscopic, isothermal titration calorimetry and molecular modeling studies.. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 206 (384-395). [PMID:30170174] |
24. Na Wei,Zhenjia Zheng,Yuhua Wang,Yanduo Tao,Yun Shao,Shuyun Zhu,Jinmao You,Xian-En Zhao. (2017-04-04) Rapid and sensitive determination of multiple endocrine-disrupting chemicals by ultrasound-assisted in situ derivatization dispersive liquid-liquid microextraction coupled with ultra-high-performance liquid chromatography/tandem mass spectrometry.. Rapid communications in mass spectrometry : RCM, 31 ((11)): (937-950). [PMID:28370680] |