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AGC:Containing PKA, PKG, PKC families
4-[(4-hydroxycyclohexyl)amino]-N-(1-phenylcyclopropyl)imidazo[1,2-a]quinoxaline-8-carboxamide , CAS No.H609133, Inhibitor of Microtubule associated serine/threonine kinase 3;Inhibitor of mitogen-activated protein kinase 8

4-[(4-hydroxycyclohexyl)amino]-N-(1-phenylcyclopropyl)imidazo[1,2-a]quinoxaline-8-carboxamide , CAS No.H609133, Inhibitor of Microtubule associated serine/threonine kinase 3;Inhibitor of mitogen-activated protein kinase 8

Item Number

H609133

Grouped product items
SKU	Size	Availability	Price	Qty
H609133-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$572.90
H609133-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,000.90

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Basic Description

Synonyms	compound 35
Specifications & Purity	Moligand™
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Inhibitor of Microtubule associated serine/threonine kinase 3;Inhibitor of mitogen-activated protein kinase 8

IUPAC Name	4-[(4-hydroxycyclohexyl)amino]-N-(1-phenylcyclopropyl)imidazo[1,2-a]quinoxaline-8-carboxamide
INCHI	InChI=1S/C26H27N5O2/c32-20-9-7-19(8-10-20)28-23-24-27-14-15-31(24)22-16-17(6-11-21(22)29-23)25(33)30-26(12-13-26)18-4-2-1-3-5-18/h1-6,11,14-16,19-20,32H,7-10,12-13H2,(H,28,29)(H,30,33)
InChi Key	YOOLXKXFWTXRHM-UHFFFAOYSA-N
Canonical SMILES	OC1CCC(CC1)Nc1nc2ccc(cc2n2c1ncc2)C(=O)NC1(CC1)c1ccccc1
Isomeric SMILES	C1CC(CCC1NC2=NC3=C(C=C(C=C3)C(=O)NC4(CC4)C5=CC=CC=C5)N6C2=NC=C6)O
PubChem CID	72164440

PubChem CID	72164440
ChEMBL Ligand	CHEMBL2420572

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1. Li B, Cociorva OM, Nomanbhoy T, Weissig H, Li Q, Nakamura K, Liyanage M, Zhang MC, Shih AY, Aban A et al.. (2013) Hit-to-lead optimization and kinase selectivity of imidazo[1,2-a]quinoxalin-4-amine derived JNK1 inhibitors.. Bioorg Med Chem Lett, 23 (18): (5217-22). [PMID:23916259]

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