Call +1 (833) 552-7181 or Contact us Earn $25 in coupons on your first order with Aladdin!
Toggle Nav
My Cart
Search
Advanced Search
Menu
Sign In
྾
main product photo

4',5-Dihydroxyflavone - 10mM in DMSO, high purity , CAS No.6665-67-4

2 Citations
  • 10mM in DMSO
Item Number
D425354
Grouped product items
SKUSizeAvailabilityPrice Qty
D425354-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$69.90
Add to Wish List Compare
Bulk Order  SDS  DATASHEET

Carbohydrate Metabolism Inhibitors

Basic Description

Synonyms4',5-Dihydroxyflavone | 6665-67-4 | 5,4'-Dihydroxyflavone | 5-Hydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one | 5-hydroxy-2-(4-hydroxyphenyl)chromen-4-one | CHEMBL484662 | 4H-1-Benzoicpyran-4-one, 5-hydroxy-2-(4-hydroxyphenyl)- | 5,4''-dihydroxyflavone | ST057730 | 5,4''''-Di
Specifications & Purity10mM in DMSO
Biochemical and Physiological Mechanisms4',5-Dihydroxyflavone inhibits soybean LOX-1 and yeast α-glucosidase.
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
Product Description

Information

4',5-Dihydroxyflavone 4',5-Dihydroxyflavone inhibits soybean LOX-1 and yeast α-glucosidase .

Associated Targets(Human)

ALOX5 Tclin Arachidonate 5-lipoxygenase (6568 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AR Tclin Androgen Receptor (11781 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PPARG Tclin Peroxisome proliferator-activated receptor gamma (15191 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PPARA Tclin Peroxisome proliferator-activated receptor alpha (9197 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
LCK Tclin Tyrosine-protein kinase LCK (9212 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NEU2 Tbio Sialidase 2 (382 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RAF1 Tclin Serine/threonine-protein kinase RAF (4169 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FBP1 Tchem Fructose-1,6-bisphosphatase (1199 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HPGD Tchem 15-hydroxyprostaglandin dehydrogenase [NAD+] (24926 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RGS4 Tchem Regulator of G-protein signaling 4 (13867 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MEN1 Tchem Menin/Histone-lysine N-methyltransferase MLL (48157 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Ppard Peroxisome proliferator-activated receptor delta (358 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mapk1 MAP kinase ERK2 (650 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
LOX1.1 Seed lipoxygenase-1 (463 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mapt Microtubule-associated protein tau (6 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ip6k2 Inositol hexakisphosphate kinase 2 (3 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 5-hydroxy-2-(4-hydroxyphenyl)chromen-4-one
INCHI InChI=1S/C15H10O4/c16-10-6-4-9(5-7-10)14-8-12(18)15-11(17)2-1-3-13(15)19-14/h1-8,16-17H
InChi Key OKRNDQLCMXUCGG-UHFFFAOYSA-N
Canonical SMILES C1=CC(=C2C(=C1)OC(=CC2=O)C3=CC=C(C=C3)O)O
Isomeric SMILES C1=CC(=C2C(=C1)OC(=CC2=O)C3=CC=C(C=C3)O)O
PubChem CID 165521
Molecular Weight 254.24

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Related Documents

 SDS

 Specification Sheet

Citations of This Product

How to Cite Aladdin Scientific Products?
1. Shumiao Yu, Caicai Xu, Tao Tang, Yiyi Zhang, Kokoette Effiong, Jing Hu, Yonghong Bi, Xi Xiao.  (2023)  Down-regulation of iron/zinc ion transport and toxin synthesis in Microcystis aeruginosa exposed to 5,4′-dihydroxyflavone.  JOURNAL OF HAZARDOUS MATERIALS,  460  (132396).  [PMID:37672994] [10.1016/j.jhazmat.2023.132396]
2. Shumiao Yu, Chao Li, Caicai Xu, Kokoette Effiong, Xi Xiao.  (2019)  Understanding the inhibitory mechanism of antialgal allelochemical flavonoids from genetic variations: Photosynthesis, toxin synthesis and nutrient utility.  ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,  177  (18).  [PMID:30954008] [10.1016/j.ecoenv.2019.03.097]

References

1. Shumiao Yu, Caicai Xu, Tao Tang, Yiyi Zhang, Kokoette Effiong, Jing Hu, Yonghong Bi, Xi Xiao.  (2023)  Down-regulation of iron/zinc ion transport and toxin synthesis in Microcystis aeruginosa exposed to 5,4′-dihydroxyflavone.  JOURNAL OF HAZARDOUS MATERIALS,  460  (132396).  [PMID:37672994] [10.1016/j.jhazmat.2023.132396]
2. Shumiao Yu, Chao Li, Caicai Xu, Kokoette Effiong, Xi Xiao.  (2019)  Understanding the inhibitory mechanism of antialgal allelochemical flavonoids from genetic variations: Photosynthesis, toxin synthesis and nutrient utility.  ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,  177  (18).  [PMID:30954008] [10.1016/j.ecoenv.2019.03.097]

Solution Calculators

Privacy Policy Website Terms of Use Return policy Terms and Conditions of Sale Cookie Policy Sales Policy
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
Copyright © 2023-present Aladdin Scientific Corp . All rights reserved.