Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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A105809-250mg | 250mg | In stock | $69.90 | |
A105809-500mg | 500mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $121.90 | |
A105809-1g | 1g | In stock | $128.90 | |
A105809-5g | 5g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $952.90 |
Selective COX-3 inhibitor
Synonyms | APAP | Cosutone | Paracetamol | Pyrinazine | Dirox | Exdol | Febrolin | N-Acetyl-p-aminophenol | Suppap | Acenol | 4-Acetamidophenol | Atralidon | Banesin | Panets | Tylenol | Deminofen | Duracetamol | Momentum | Apamide | Injectapap | Homoolan | Datril | |
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Specifications & Purity | analytical standard, ≥99.5% |
Biochemical and Physiological Mechanisms | Selective COX-3 inhibitor (IC 50 = 460 μM). NSAID with widely used analgesic and antipyretic effects. Blood-brain barrier permeable. |
Shipped In | Normal |
Grade | analytical standard |
Action Type | INHIBITOR |
Mechanism of action | Vanilloid receptor opener |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
ALogP | 0.5 |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | N-(4-hydroxyphenyl)acetamide |
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INCHI | InChI=1S/C8H9NO2/c1-6(10)9-7-2-4-8(11)5-3-7/h2-5,11H,1H3,(H,9,10) |
InChi Key | RZVAJINKPMORJF-UHFFFAOYSA-N |
Canonical SMILES | CC(=O)NC1=CC=C(C=C1)O |
Isomeric SMILES | CC(=O)NC1=CC=C(C=C1)O |
WGK Germany | 1 |
RTECS | AE4200000 |
PubChem CID | 1983 |
Molecular Weight | 151.16 |
Beilstein | 2208089 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
E2421043 | Certificate of Analysis | Jul 31, 2023 | A105809 |
G2328069 | Certificate of Analysis | Jul 31, 2023 | A105809 |
H2309518 | Certificate of Analysis | Jul 31, 2023 | A105809 |
I2301210 | Certificate of Analysis | Jul 31, 2023 | A105809 |
C2412070 | Certificate of Analysis | Jul 29, 2023 | A105809 |
G2327010 | Certificate of Analysis | Jul 29, 2023 | A105809 |
G2214126 | Certificate of Analysis | Jun 29, 2022 | A105809 |
G2214127 | Certificate of Analysis | Jun 29, 2022 | A105809 |
G2214128 | Certificate of Analysis | Jun 29, 2022 | A105809 |
G2214129 | Certificate of Analysis | Jun 29, 2022 | A105809 |
K2201610 | Certificate of Analysis | Jun 29, 2022 | A105809 |
K2224159 | Certificate of Analysis | Jun 29, 2022 | A105809 |
Sensitivity | Light sensitive. |
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Melt Point(°C) | 168-172°C |
Pictogram(s) | GHS08, GHS09, GHS07 |
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Signal | Danger |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H412:Harmful to aquatic life with long lasting effects H302:Harmful if swallowed |
Precautionary Statements | P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. |
WGK Germany | 1 |
RTECS | AE4200000 |
Merck Index | 47 |
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2. Hongwei Luo, Dongli Wang, Yifeng Zeng, Dongqin He, Ganning Zeng, Juan Xu, Xiangliang Pan. (2024) Iron-doped swine bone char as hydrogen peroxide activator for efficient removal of acetaminophen in water. SCIENCE OF THE TOTAL ENVIRONMENT, 912 (168833). [PMID:38036120] [10.1016/j.scitotenv.2023.168833] |
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24. Zongyan Lu, Hao Guo, Xiaoqin Wei, Lei Sun, Zhilan Pan, Bingqing Liu, Yinsheng Liu, Jiaxi Xu, Jiaying Tian, Wu Yang. (2023) A novel electrochemical sensing platform based on covalent organic frameworks/WC/NH2-MWCNT for highly selective determination of acetaminophen and 4-aminophenol. MICROCHEMICAL JOURNAL, 193 (109075). [PMID:] [10.1016/j.microc.2023.109075] |
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26. Zhiming Jiang, Guangyu Li, Mingxiao Zhang. (2017) A Novel Electrochemical Sensor Based on SH-β-cyclodextrin Functionalized Gold Nanoparticles/Reduced-Graphene Oxide Nanohybrids for Ultrasensitive Electrochemical Sensing of Acetaminophen and Ofloxacin. International Journal of Electrochemical Science, 12 (5157). [PMID:] [10.20964/2017.06.28] |
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