4-Aminodiphenylamine - 98%, high purity , CAS No.101-54-2

9 Citations
  • ≥98%
Item Number
A104007
Grouped product items
SKUSizeAvailabilityPrice Qty
A104007-25g
25g
In stock
$13.90
A104007-100g
100g
In stock
$47.90
A104007-500g
500g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$53.90

Basic Description

Synonyms4-Aminodiphenylamine | N-Phenyl-p-phenylenediamine | 101-54-2 | N1-phenylbenzene-1,4-diamine | p-Anilinoaniline | Azosalt R | P-AMINODIPHENYLAMINE | p-Semidine | Luxan Black R | Semidine | N-Phenyl-1,4-phenylenediamine | N-4'-Bianiline | N-Phenyl-1,4-benzenediamine | N-Phenyl-p-am
Specifications & Purity≥98%
Storage TempProtected from light
Shipped InNormal

Associated Targets(Human)

CYP1A2 Tchem Cytochrome P450 1A2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CYP2D6 Tclin Cytochrome P450 2D6 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CYP2C19 Tchem Cytochrome P450 2C19 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CYP3A4 Tclin Cytochrome P450 3A4 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
EHMT2 Tchem Histone-lysine N-methyltransferase EHMT2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
NR3C1 Tclin Glucocorticoid receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CBX1 Tbio Chromobox protein homolog 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CYP2C9 Tchem Cytochrome P450 2C9 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GMNN Tbio Geminin (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
RUNX1 Tbio Runt-related transcription factor 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
RORC Tchem Nuclear receptor ROR-gamma (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
RAPGEF3 Tchem Rap guanine nucleotide exchange factor 3 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
FTL Tbio Ferritin light chain (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
FPR1 Tchem fMet-Leu-Phe receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SMAD3 Tchem Mothers against decapentaplegic homolog 3 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
POLI Tchem DNA polymerase iota (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ALOX12 Tchem Arachidonate 12-lipoxygenase, 12S-type (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
L3MBTL1 Tchem Lethal(3)malignant brain tumor-like protein 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ALOX15B Tchem Arachidonate 15-lipoxygenase B (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
NR1H4 Tclin Bile acid receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
BAZ2B Tchem Bromodomain adjacent to zinc finger domain protein 2B (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
AR Tclin Androgen receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ALDH1A1 Tchem Retinal dehydrogenase 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
MAPT Tclin Microtubule-associated protein tau (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HTT Tchem Huntingtin (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GLP1R Tclin Glucagon-like peptide 1 receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
IDH1 Tclin Isocitrate dehydrogenase [NADP] cytoplasmic (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
TP53 Tchem Cellular tumor antigen p53 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PPARD Tchem Peroxisome proliferator-activated receptor delta (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
NFE2L2 Tchem Nuclear factor erythroid 2-related factor 2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
IDO1 Tchem Indoleamine 2,3-dioxygenase 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
KDM4A Tchem Lysine-specific demethylase 4A (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
NR3C1 Tclin Glucocorticoid receptor (14987 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AR Tclin Androgen Receptor (11781 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALOX15B Tchem Arachidonate 15-lipoxygenase, type II (7244 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALOX12 Tchem Arachidonate 12-lipoxygenase (3262 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NR1H4 Tclin Bile acid receptor FXR (6228 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2D6 Tclin Cytochrome P450 2D6 (33882 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GLP1R Tclin Glucagon-like peptide 1 receptor (111429 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP1A2 Tchem Cytochrome P450 1A2 (26471 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2C9 Tchem Cytochrome P450 2C9 (32119 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2C19 Tchem Cytochrome P450 2C19 (29246 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FPR1 Tchem Formyl peptide receptor 1 (1372 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TP53 Tchem Cellular tumor antigen p53 (48468 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HepG2 (196354 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
IDO1 Tchem Indoleamine 2,3-dioxygenase (6650 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
POLI Tchem DNA polymerase iota (116820 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTT Tchem Huntingtin (19182 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM4A Tchem Lysine-specific demethylase 4A (52245 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
L3MBTL1 Tchem Lethal(3)malignant brain tumor-like protein 1 (14536 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SMAD3 Tchem Mothers against decapentaplegic homolog 3 (68039 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GMNN Tbio Geminin (128009 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CBX1 Tbio Chromobox protein homolog 1 (92434 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BAZ2B Tchem Bromodomain adjacent to zinc finger domain protein 2B (56204 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
IDH1 Tclin Isocitrate dehydrogenase [NADP] cytoplasmic (40980 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RAPGEF3 Tchem Rap guanine nucleotide exchange factor 3 (15528 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RUNX1 Tbio Runt-related transcription factor 1/Core-binding factor subunit beta (7867 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Cruzipain (33337 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ppard Peroxisome proliferator-activated receptor delta (358 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
INS1 (2867 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HT-22 (3261 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TGR Thioredoxin glutathione reductase (28579 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mapt Microtubule-associated protein tau (6 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rorc Nuclear receptor ROR-gamma (89407 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ffp 4'-phosphopantetheinyl transferase ffp (24982 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FTL Ferritin light chain (43324 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NS1 Nonstructural protein 1 (33327 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

Pubchem Sid488180484
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488180484
IUPAC Name 4-N-phenylbenzene-1,4-diamine
INCHI InChI=1S/C12H12N2/c13-10-6-8-12(9-7-10)14-11-4-2-1-3-5-11/h1-9,14H,13H2
InChi Key ATGUVEKSASEFFO-UHFFFAOYSA-N
Canonical SMILES C1=CC=C(C=C1)NC2=CC=C(C=C2)N
Isomeric SMILES C1=CC=C(C=C1)NC2=CC=C(C=C2)N
WGK Germany 3
RTECS ST3150000
PubChem CID 7564
UN Number 1673
Packing Group III
Molecular Weight 184.24
Beilstein 908935
Reaxy-Rn 908935

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

8 results found

Lot NumberCertificate TypeDateItem
F2406116Certificate of AnalysisMar 23, 2024 A104007
L1910165Certificate of AnalysisOct 19, 2023 A104007
E2310733Certificate of AnalysisMay 22, 2023 A104007
B2309216Certificate of AnalysisFeb 14, 2023 A104007
B2309320Certificate of AnalysisFeb 11, 2023 A104007
H2401017Certificate of AnalysisNov 29, 2021 A104007
J2312089Certificate of AnalysisNov 29, 2021 A104007
K2116076Certificate of AnalysisNov 29, 2021 A104007

Chemical and Physical Properties

SolubilityHard to dissolve in water, soluble in ethanol, ether, and dilute hydrochloric acid.
SensitivityLight sensitive.
Flash Point(°F)379.4 °F
Flash Point(°C)193 °C
Boil Point(°C)354°C
Melt Point(°C)68-72°C

Safety and Hazards(GHS)

Pictogram(s) GHS09,   GHS07
Signal Warning
Hazard Statements

H319:Causes serious eye irritation

H302:Harmful if swallowed

H317:May cause an allergic skin reaction

H400:Very toxic to aquatic life

H410:Very toxic to aquatic life with long lasting effects

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P273:Avoid release to the environment.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P270:Do not eat, drink or smoke when using this product.

P272:Contaminated work clothing should not be allowed out of the workplace.

P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention.

P362+P364:Take off contaminated clothing and wash it before reuse.

P391:Collect spillage.

P330:Rinse mouth.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P301+P317:IF SWALLOWED: Get medical help.

P337+P317:If eye irritation persists: Get medical help.

WGK Germany 3
RTECS ST3150000
Reaxy-Rn 908935
Class 6.1

Related Documents

Citations of This Product

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2. Jiancong Lu, Biye Yang, Dan Lu, Yukun Qian, Tianzhuang Ye, Ge Li, Jing Wang, Zhikan Yao, Lei Jiao, Lin Zhang.  (2023)  Secondary interfacial reaction of p-aminodiphenylamine enables polyamide reverse osmosis membrane with enhanced and regenerative chlorine resistance.  JOURNAL OF MEMBRANE SCIENCE,  688  (4): (122148).  [PMID:21723284]
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9. Yang Zou, Lan Li, Yuan Li, Si Chen, Xianhua Xie, Xin Jin, Xiaodan Wang, Chuanrui Ma, Guanwei Fan, Wei Wang.  (2021)  Restoring Cardiac Functions after Myocardial Infarction–Ischemia/Reperfusion via an Exosome Anchoring Conductive Hydrogel.  ACS Applied Materials & Interfaces,  13  (48): (56892–56908).  [PMID:34823355]

References

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8. Tetsuo Yamano,Mitsuru Shimizu.  (2009-04-03)  Skin sensitization potency and cross-reactivity of p-phenylenediamine and its derivatives evaluated by non-radioactive murine local lymph node assay and guinea-pig maximization test..  Contact dermatitis,  60  ((4)): (193-198).  [PMID:19338586]
9. S K Khanna,P Tewari,A Joshi,G B Singh.  (1987-06-01)  Studies on the skin uptake and efflux kinetics of N-phenyl-p-phenylenediamine: an aromatic amine intermediate..  International journal of cosmetic science,  ((3)): (137-147).  [PMID:19456976]
10. Ute F Röhrig,Loay Awad,Aurélien Grosdidier,Pierre Larrieu,Vincent Stroobant,Didier Colau,Vincenzo Cerundolo,Andrew J G Simpson,Pierre Vogel,Benoît J Van den Eynde,Vincent Zoete,Olivier Michielin.  (2010-01-09)  Rational design of indoleamine 2,3-dioxygenase inhibitors..  Journal of medicinal chemistry,  53  ((3)): (1172-1189).  [PMID:20055453]
11. Starlet Thanjam,M Francklin Philips,S Komathi,P Manisankar,C Sivakumar,A Gopalan,Kwang-Pill Lee.  (2011-06-04)  Course of poly(4-aminodiphenylamine)/Ag nanocomposite formation through UV-vis spectroscopy..  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy,  79  ((5)): (1256-1266).  [PMID:21636315]
12. Althea Elliott,Aby Joiakim,Patricia A Mathieu,Zofia Duniec-Dmuchowski,Thomas A Kocarek,John J Reiners.  (2012-02-22)  p-Anilinoaniline enhancement of dioxin-induced CYP1A1 transcription and aryl hydrocarbon receptor occupancy of CYP1A1 promoter: role of the cell cycle..  Drug metabolism and disposition: the biological fate of chemicals,  40  ((5)): (1032-1040).  [PMID:22344700]
13. Yaozu Liao,Xia Wang,Wei Qian,Ying Li,Xiaoyan Li,Deng-Guang Yu.  (2012-08-18)  Bulk synthesis, optimization, and characterization of highly dispersible polypyrrole nanoparticles toward protein separation using nanocomposite membranes..  Journal of colloid and interface science,  386  ((1)): (148-157).  [PMID:22897951]
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16. Khouloud Jlassi,A Bahgat Radwan,Kishor Kumar Sadasivuni,Miroslav Mrlik,Aboubakr M Abdullah,Mohamed M Chehimi,Igor Krupa.  (2018-09-08)  Anti-corrosive and oil sensitive coatings based on epoxy/polyaniline/magnetite-clay composites through diazonium interfacial chemistry..  Scientific reports,  ((1)): (13369-13369).  [PMID:30190528]
17. Jia Liu,Yoon Seok Kim,Claire E Richardson,Ariane Tom,Charu Ramakrishnan,Fikri Birey,Toru Katsumata,Shucheng Chen,Cheng Wang,Xiao Wang,Lydia-Marie Joubert,Yuanwen Jiang,Huiliang Wang,Lief E Fenno,Jeffrey B-H Tok,Sergiu P Pașca,Kang Shen,Zhenan Bao,Karl Deisseroth.  (2020-03-21)  Genetically targeted chemical assembly of functional materials in living cells, tissues, and animals..  Science (New York, N.Y.),  367  ((6484)): (1372-1376).  [PMID:32193327]
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19. A Tosti,C Varotti,G Minghetti,F Bardazzi,S Pileri,M T Rivano,S Veronesi.  (1986-01-01)  Immunologic characterization of infiltrating cells in flare-up reactions..  Contact dermatitis,  14  ((1)): (62-62).  [PMID:3485030]
20. J C Picciano,R W Schnetzinger,W E Morris,B A Wolf,D E Rodwell.  (1984-01-01)  Evaluation of the teratogenic potential of the oxidative dye N-phenyl-para-phenylenediamine..  Drug and chemical toxicology,  ((2)): (167-176).  [PMID:6479065]
21. M A Kaniwa,K Isama,A Nakamura,H Kantoh,M Itoh,M Ichikawa,R Hayakawa.  (1994-01-01)  Identification of causative chemicals of allergic contact dermatitis using a combination of patch testing in patients and chemical analysis. Application to cases from industrial rubber products..  Contact dermatitis,  30  ((1)): (20-25).  [PMID:8156758]
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23. C Skudlik,E Meyer,H Allmers,E Domagalski,S M John.  (2011-09-09)  [Endemic air-borne contact dermatitis? Frequent occurrence of a rare contact allergy in a waste collection facility]..  Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete,  62  ((10)): (765-769).  [PMID:21901562]
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Solution Calculators