Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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A111957-10g | 10g | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $15.90 | |
A111957-25g | 25g | In stock | $31.90 | |
A111957-100g | 100g | In stock | $100.90 | |
A111957-250g | 250g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $200.90 | |
A111957-500g | 500g | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $320.90 |
Synonyms | 4-(Aminomethyl)benzoic acid | 4-Carboxybenzylamine | Aminomethylbenzoic acid | Pamba | 4-Aminomethylbenzoic acid |
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Specifications & Purity | Moligand™, ≥97% |
Storage Temp | Argon charged |
Shipped In | Normal |
Grade | Moligand™ |
Action Type | INHIBITOR |
Mechanism of action | Inhibitor of Peptide transporter 1;Inhibitor of Peptide transporter 2 |
Note | 2.5kg,5g售完停产不再备货 |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Pubchem Sid | 488183689 |
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Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488183689 |
IUPAC Name | 4-(aminomethyl)benzoic acid |
INCHI | InChI=1S/C8H9NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4H,5,9H2,(H,10,11) |
InChi Key | QCTBMLYLENLHLA-UHFFFAOYSA-N |
Canonical SMILES | C1=CC(=CC=C1CN)C(=O)O |
Isomeric SMILES | C1=CC(=CC=C1CN)C(=O)O |
WGK Germany | 3 |
PubChem CID | 65526 |
Molecular Weight | 151.16 |
Beilstein | 1100606 |
Reaxy-Rn | 1100606 |
PubChem CID | 65526 |
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CAS Registry No. | 56-91-7 |
ChEMBL Ligand | CHEMBL328875 |
Wikipedia | Aminomethylbenzoic acid |
RCSB PDB Ligand | 4AZ |
DrugCentral Ligand | 22 |
PubChem SID | 488183689 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
G2029008 | Certificate of Analysis | May 08, 2024 | A111957 |
C2429123 | Certificate of Analysis | Mar 13, 2024 | A111957 |
C2429124 | Certificate of Analysis | Mar 13, 2024 | A111957 |
C2429122 | Certificate of Analysis | Mar 13, 2024 | A111957 |
C2405168 | Certificate of Analysis | Feb 26, 2024 | A111957 |
C2405169 | Certificate of Analysis | Feb 26, 2024 | A111957 |
C2405172 | Certificate of Analysis | Feb 26, 2024 | A111957 |
C2405174 | Certificate of Analysis | Feb 26, 2024 | A111957 |
C2405181 | Certificate of Analysis | Feb 26, 2024 | A111957 |
C23161366 | Certificate of Analysis | Mar 24, 2023 | A111957 |
C23161340 | Certificate of Analysis | Mar 22, 2023 | A111957 |
C23161440 | Certificate of Analysis | Mar 22, 2023 | A111957 |
B2325232 | Certificate of Analysis | Mar 03, 2023 | A111957 |
H2224251 | Certificate of Analysis | Oct 28, 2021 | A111957 |
Solubility | Slightly soluble in water. Insoluble in ethanol, benzene and chloroform. |
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Sensitivity | Moisture sensitive |
Melt Point(°C) | ≥300°C |
Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
WGK Germany | 3 |
Reaxy-Rn | 1100606 |
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2. M R Rejante,I J Byeon,M Llinás. (1991-11-19) Ligand specificity of human plasminogen kringle 4.. Biochemistry, 30 ((46)): (11081-11092). [PMID:1657159] |
3. G N Vishniak,K E Kharlamova,G T Gurosheva,A M Zavernaia,I A Golovnia. (1993-07-01) [Amben and galascorbin in the combined treatment of ulcerative-necrotic lesions of the oral mucosa].. Stomatologiia, 72 ((3)): (24-26). [PMID:8236292] |
4. V Mikol,P V LoGrasso,B R Boettcher. (1996-03-08) Crystal structures of apolipoprotein(a) kringle IV37 free and complexed with 6-aminohexanoic acid and with p-aminomethylbenzoic acid: existence of novel and expected binding modes.. Journal of molecular biology, 256 ((4)): (751-761). [PMID:8642595] |
5. Darcel NP, Liou AP, Tomé D, Raybould HE. (2005) Activation of vagal afferents in the rat duodenum by protein digests requires PepT1.. J Nutr, 135 (6): (1491-5). [PMID:15930458] [10.1021/op500134e] |
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7. M Du,B Tang,H Shen,S Wang,T Sun,C Zhang. (2002-05-23) [Host-guest molecule interaction mechanism of hemostatics with liposomes and red blood cells studied with fluorescence polarimetric method].. Yao xue xue bao = Acta pharmaceutica Sinica, 33 ((5)): (362-368). [PMID:12017004] |
8. Baihua Hu,Kristi Yi Fan,Kristie Bridges,Rajiv Chopra,Frank Lovering,Derek Cole,Ping Zhou,John Ellingboe,Guixiang Jin,Rebecca Cowling,Jonathan Bard. (2004-06-05) Synthesis and SAR of bis-statine based peptides as BACE 1 inhibitors.. Bioorganic & medicinal chemistry letters, 14 ((13)): (3457-3460). [PMID:15177452] |
9. Balazs Debreceni,Viktoria Farkas,Gabor M Fischer,Attila Sandor. (2005-11-29) Effect of aromatic ring-containing drugs on carnitine biosynthesis in rats with special regard to p-aminomethylbenzoic acid.. Metabolism: clinical and experimental, 54 ((12)): (1582-1586). [PMID:16311089] |
10. Guo-qing Ding,Zhou-jun Shen,Jing Lu,Xiao-dong Jin,Jun Chen,Shi-fang Shi. (2005-12-02) [Clinical investigation on the effect of intravesical instillation of antifibrinolytic agents with bacillus Calmette-Guerin on preventing bladder cancer recurrence].. Zhonghua wai ke za zhi [Chinese journal of surgery], 43 ((22)): (1457-1460). [PMID:16318813] |
11. Francesc Yraola, Silvia García-Vicente, Juan Fernandez-Recio, Fernando Albericio, Antonio Zorzano, Luc Marti, Miriam Royo,. (2006-10-13) New efficient substrates for semicarbazide-sensitive amine oxidase/VAP-1 enzyme: analysis by SARs and computational docking.. Journal of medicinal chemistry, 49 ((21)): ( 6197-6208 ). [PMID:17034126] |
12. Quan-Min Li,Zhan-Jun Yang. (2006-11-18) Spectrophotometric determination of aminomethylbenzoic acid using sodium 1,2-naphthoquinone-4-sulfonate as the chemical derivative chromogenic reagent.. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 66 ((3)): (656-661). [PMID:17110157] |
13. Zhou-Jun Shen,Yi Wang,Guo-Qing Ding,Chun-Wu Pan,Rong-Ming Zheng. (2007-08-01) Study on enhancement of fibronectin-mediated bacillus Calmette-Guérin attachment to urinary bladder wall in rabbits.. World journal of urology, 25 ((5)): (525-529). [PMID:17665201] |
14. Hanwen Sun,Lijing Wei,Yuanyuan Wu,Na Liu. (2010-06-24) Simultaneous determination of aminomethylbenzoic acid, cefminox sodium and etamsylate in human urine by capillary electrophoresis.. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 878 ((21)): (1899-1903). [PMID:20570576] |
15. Shingo Nakajima,Tohru Hira,Hiroshi Hara. (2012-06-01) Calcium-sensing receptor mediates dietary peptide-induced CCK secretion in enteroendocrine STC-1 cells.. Molecular nutrition & food research, 56 ((5)): (753-760). [PMID:22648622] |
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18. H Dobrev,L Popova,D Vlashev. (1996-10-01) Proteinase inhibitors and pemphigus vulgaris. An in vitro and in vivo study.. Archives of dermatological research, 288 ((11)): (648-655). [PMID:8931866] |
19. Erach R Talaty,Travis J Cooper,Sandra Osburn,Michael J Van Stipdonk. (2006-10-27) Collision-induced dissociation of protonated tetrapeptides containing beta-alanine, gamma-aminobutyric acid, epsilon-aminocaproic acid or 4-aminomethylbenzoic acid residues.. Rapid communications in mass spectrometry : RCM, 20 ((22)): (3443-3455). [PMID:17066369] |
20. Sandra Osburn,Sila Ochola,Erach Talaty,Michael Van Stipdonk. (2007-09-29) Influence of a 4-aminomethylbenzoic acid residue on competitive fragmentation pathways during collision-induced dissociation of metal-cationized peptides.. Rapid communications in mass spectrometry : RCM, 21 ((21)): (3409-3419). [PMID:17902197] |
21. Carlos F R A C Lima,Lígia R Gomes,Luís M N B F Santos. (2007-10-05) Substituent effects on the energetics and aromaticity of aminomethylbenzoic acids.. The journal of physical chemistry. A, 111 ((42)): (10598-10603). [PMID:17914759] |
22. Chun-Wu Pan,Zhou-Jun Shen,Guo-Qing Ding. (2008-02-22) The effect of intravesical instillation of antifibrinolytic agents on bacillus Calmette-Guerin treatment of superficial bladder cancer: a pilot study.. The Journal of urology, 179 ((4)): (1307-1311). [PMID:18289576] |