4-(Aminomethyl)benzoic acid - 97%, high purity , CAS No.56-91-7, Inhibitor of Peptide transporter 1;Inhibitor of Peptide transporter 2

Item Number
A111957
Grouped product items
SKUSizeAvailabilityPrice Qty
A111957-10g
10g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$15.90
A111957-25g
25g
In stock
$31.90
A111957-100g
100g
In stock
$100.90
A111957-250g
250g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$200.90
A111957-500g
500g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$320.90

Basic Description

Synonyms4-(Aminomethyl)benzoic acid | 4-Carboxybenzylamine | Aminomethylbenzoic acid | Pamba | 4-Aminomethylbenzoic acid
Specifications & PurityMoligand™, ≥97%
Storage TempArgon charged
Shipped InNormal
GradeMoligand™
Action TypeINHIBITOR
Mechanism of actionInhibitor of Peptide transporter 1;Inhibitor of Peptide transporter 2
Note2.5kg,5g售完停产不再备货

Associated Targets(Human)

SLC15A2 Tchem Solute carrier family 15 member 2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SLC15A1 Tchem Solute carrier family 15 member 1 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PRSS1 Tclin Trypsin I (2306 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2D6 Tclin Cytochrome P450 2D6 (33882 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP1A2 Tchem Cytochrome P450 1A2 (26471 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2C9 Tchem Cytochrome P450 2C9 (32119 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2C19 Tchem Cytochrome P450 2C19 (29246 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
A498 (42825 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ACHN (49357 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CAKI-1 (44928 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DU-145 (51482 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HL-60 (67320 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HT-29 (80576 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
K562 (73714 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KM12 (47707 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
M14 (47487 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MOLT-4 (49676 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OVCAR-3 (48710 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OVCAR-4 (44535 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OVCAR-5 (45555 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OVCAR-8 (47708 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PC-3 (62116 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RXF 393 (41971 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SF-295 (48000 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SK-MEL-28 (48833 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SK-MEL-5 (47095 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SN12C (47755 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SNB-19 (46794 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TK-10 (45540 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
U-251 (51189 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UACC-257 (46019 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UACC-62 (47335 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UO-31 (46270 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
786-0 (47912 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
A549 (127892 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NCI/ADR-RES (33767 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
T47D (39041 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EKVX (44102 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NCI-H322M (45589 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HCC 2998 (41480 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HCT-116 (91556 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HOP-92 (41141 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NCI-H460 (60772 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SF-268 (49410 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
IGROV-1 (47897 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
LOX IMVI (44321 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HOP-62 (47048 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MDA-MB-435 (38290 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MDA-N (28205 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Malme-3M (44254 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MDA-MB-231 (73002 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

AOC3 Amine oxidase, copper containing (44 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Helicobacter pylori (3113 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus aureus (210822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Escherichia coli (133304 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Pubchem Sid488183689
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488183689
IUPAC Name 4-(aminomethyl)benzoic acid
INCHI InChI=1S/C8H9NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4H,5,9H2,(H,10,11)
InChi Key QCTBMLYLENLHLA-UHFFFAOYSA-N
Canonical SMILES C1=CC(=CC=C1CN)C(=O)O
Isomeric SMILES C1=CC(=CC=C1CN)C(=O)O
WGK Germany 3
PubChem CID 65526
Molecular Weight 151.16
Beilstein 1100606
Reaxy-Rn 1100606

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

14 results found

Lot NumberCertificate TypeDateItem
G2029008Certificate of AnalysisMay 08, 2024 A111957
C2429123Certificate of AnalysisMar 13, 2024 A111957
C2429124Certificate of AnalysisMar 13, 2024 A111957
C2429122Certificate of AnalysisMar 13, 2024 A111957
C2405168Certificate of AnalysisFeb 26, 2024 A111957
C2405169Certificate of AnalysisFeb 26, 2024 A111957
C2405172Certificate of AnalysisFeb 26, 2024 A111957
C2405174Certificate of AnalysisFeb 26, 2024 A111957
C2405181Certificate of AnalysisFeb 26, 2024 A111957
C23161366Certificate of AnalysisMar 24, 2023 A111957
C23161340Certificate of AnalysisMar 22, 2023 A111957
C23161440Certificate of AnalysisMar 22, 2023 A111957
B2325232Certificate of AnalysisMar 03, 2023 A111957
H2224251Certificate of AnalysisOct 28, 2021 A111957

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Chemical and Physical Properties

SolubilitySlightly soluble in water. Insoluble in ethanol, benzene and chloroform.
SensitivityMoisture sensitive
Melt Point(°C)≥300°C

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 3
Reaxy-Rn 1100606

Related Documents

References

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2. M R Rejante,I J Byeon,M Llinás.  (1991-11-19)  Ligand specificity of human plasminogen kringle 4..  Biochemistry,  30  ((46)): (11081-11092).  [PMID:1657159]
3. G N Vishniak,K E Kharlamova,G T Gurosheva,A M Zavernaia,I A Golovnia.  (1993-07-01)  [Amben and galascorbin in the combined treatment of ulcerative-necrotic lesions of the oral mucosa]..  Stomatologiia,  72  ((3)): (24-26).  [PMID:8236292]
4. V Mikol,P V LoGrasso,B R Boettcher.  (1996-03-08)  Crystal structures of apolipoprotein(a) kringle IV37 free and complexed with 6-aminohexanoic acid and with p-aminomethylbenzoic acid: existence of novel and expected binding modes..  Journal of molecular biology,  256  ((4)): (751-761).  [PMID:8642595]
5. Darcel NP, Liou AP, Tomé D, Raybould HE.  (2005)  Activation of vagal afferents in the rat duodenum by protein digests requires PepT1..  J Nutr,  135  (6): (1491-5).  [PMID:15930458] [10.1021/op500134e]
6. M N Iakushenko,Zh A Tkhagapsoeva,V M Bondarenko.  (1998-04-09)  [The Amben correction of disorders in the intestinal microbial colonization of newborn infants with perinatal pathology]..  Zhurnal mikrobiologii, epidemiologii, i immunobiologii,    ((1)): (77-79).  [PMID:9532694]
7. M Du,B Tang,H Shen,S Wang,T Sun,C Zhang.  (2002-05-23)  [Host-guest molecule interaction mechanism of hemostatics with liposomes and red blood cells studied with fluorescence polarimetric method]..  Yao xue xue bao = Acta pharmaceutica Sinica,  33  ((5)): (362-368).  [PMID:12017004]
8. Baihua Hu,Kristi Yi Fan,Kristie Bridges,Rajiv Chopra,Frank Lovering,Derek Cole,Ping Zhou,John Ellingboe,Guixiang Jin,Rebecca Cowling,Jonathan Bard.  (2004-06-05)  Synthesis and SAR of bis-statine based peptides as BACE 1 inhibitors..  Bioorganic & medicinal chemistry letters,  14  ((13)): (3457-3460).  [PMID:15177452]
9. Balazs Debreceni,Viktoria Farkas,Gabor M Fischer,Attila Sandor.  (2005-11-29)  Effect of aromatic ring-containing drugs on carnitine biosynthesis in rats with special regard to p-aminomethylbenzoic acid..  Metabolism: clinical and experimental,  54  ((12)): (1582-1586).  [PMID:16311089]
10. Guo-qing Ding,Zhou-jun Shen,Jing Lu,Xiao-dong Jin,Jun Chen,Shi-fang Shi.  (2005-12-02)  [Clinical investigation on the effect of intravesical instillation of antifibrinolytic agents with bacillus Calmette-Guerin on preventing bladder cancer recurrence]..  Zhonghua wai ke za zhi [Chinese journal of surgery],  43  ((22)): (1457-1460).  [PMID:16318813]
11. Francesc Yraola, Silvia García-Vicente, Juan Fernandez-Recio, Fernando Albericio, Antonio Zorzano, Luc Marti, Miriam Royo,.  (2006-10-13)  New efficient substrates for semicarbazide-sensitive amine oxidase/VAP-1 enzyme: analysis by SARs and computational docking..  Journal of medicinal chemistry,  49  ((21)): ( 6197-6208 ).  [PMID:17034126]
12. Quan-Min Li,Zhan-Jun Yang.  (2006-11-18)  Spectrophotometric determination of aminomethylbenzoic acid using sodium 1,2-naphthoquinone-4-sulfonate as the chemical derivative chromogenic reagent..  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy,  66  ((3)): (656-661).  [PMID:17110157]
13. Zhou-Jun Shen,Yi Wang,Guo-Qing Ding,Chun-Wu Pan,Rong-Ming Zheng.  (2007-08-01)  Study on enhancement of fibronectin-mediated bacillus Calmette-Guérin attachment to urinary bladder wall in rabbits..  World journal of urology,  25  ((5)): (525-529).  [PMID:17665201]
14. Hanwen Sun,Lijing Wei,Yuanyuan Wu,Na Liu.  (2010-06-24)  Simultaneous determination of aminomethylbenzoic acid, cefminox sodium and etamsylate in human urine by capillary electrophoresis..  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences,  878  ((21)): (1899-1903).  [PMID:20570576]
15. Shingo Nakajima,Tohru Hira,Hiroshi Hara.  (2012-06-01)  Calcium-sensing receptor mediates dietary peptide-induced CCK secretion in enteroendocrine STC-1 cells..  Molecular nutrition & food research,  56  ((5)): (753-760).  [PMID:22648622]
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18. H Dobrev,L Popova,D Vlashev.  (1996-10-01)  Proteinase inhibitors and pemphigus vulgaris. An in vitro and in vivo study..  Archives of dermatological research,  288  ((11)): (648-655).  [PMID:8931866]
19. Erach R Talaty,Travis J Cooper,Sandra Osburn,Michael J Van Stipdonk.  (2006-10-27)  Collision-induced dissociation of protonated tetrapeptides containing beta-alanine, gamma-aminobutyric acid, epsilon-aminocaproic acid or 4-aminomethylbenzoic acid residues..  Rapid communications in mass spectrometry : RCM,  20  ((22)): (3443-3455).  [PMID:17066369]
20. Sandra Osburn,Sila Ochola,Erach Talaty,Michael Van Stipdonk.  (2007-09-29)  Influence of a 4-aminomethylbenzoic acid residue on competitive fragmentation pathways during collision-induced dissociation of metal-cationized peptides..  Rapid communications in mass spectrometry : RCM,  21  ((21)): (3409-3419).  [PMID:17902197]
21. Carlos F R A C Lima,Lígia R Gomes,Luís M N B F Santos.  (2007-10-05)  Substituent effects on the energetics and aromaticity of aminomethylbenzoic acids..  The journal of physical chemistry. A,  111  ((42)): (10598-10603).  [PMID:17914759]
22. Chun-Wu Pan,Zhou-Jun Shen,Guo-Qing Ding.  (2008-02-22)  The effect of intravesical instillation of antifibrinolytic agents on bacillus Calmette-Guerin treatment of superficial bladder cancer: a pilot study..  The Journal of urology,  179  ((4)): (1307-1311).  [PMID:18289576]

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