4-(Benzyloxy)phenol - 98%, high purity , Tyrosinase inhibitor, CAS No.103-16-2, Tyrosinase inhibitor

Item Number
B100826
Grouped product items
SKUSizeAvailabilityPrice Qty
B100826-5g
5g
In stock
$11.90
B100826-10g
10g
In stock
$18.90
B100826-25g
25g
In stock
$35.90
B100826-100g
100g
In stock
$95.90
B100826-500g
500g
In stock
$333.90

Induces loss of epidermal melanocytes in vivo

View related series
Non heterocyclic block phenol

Basic Description

SynonymsMonobenzone | 4-Benzyloxyphenol | 103-16-2 | 4-(Benzyloxy)phenol | Hydroquinone monobenzyl ether | Benoquin | P-(BENZYLOXY)PHENOL | Benzoquin | Monobenzyl hydroquinone | Hydroquinone benzyl ether | Leucodinine | Monobenzon | Superlite | Agerite alba | 4-(Phenylmethoxy)phenol | p-Hydro
Specifications & PurityMoligand™, ≥98%
Biochemical and Physiological MechanismsInduces loss of epidermal melanocytes in vivo . Induces T-cell autoimmunity toward pigmented cells by tyrosinase haptenation and melanosome autophagy. Skin depigmentation and immunotherapy agent. Active in vivo.
Shipped InNormal
GradeMoligand™
Action TypeINHIBITOR
Mechanism of actionTyrosinase inhibitor
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Properties

ALogP3.4

Associated Targets(Human)

CTH Tchem Cystathionine gamma-lyase (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CYP1A2 Tchem Cytochrome P450 1A2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
DRD2 Tclin D(2) dopamine receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
DRD4 Tchem D(4) dopamine receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CYP3A4 Tclin Cytochrome P450 3A4 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ERBB2 Tclin Receptor tyrosine-protein kinase erbB-2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GABRA1 Tclin Gamma-aminobutyric acid receptor subunit alpha-1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ELANE Tclin Neutrophil elastase (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
EGFR Tclin Epidermal growth factor receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
AVPR1A Tclin Vasopressin V1a receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HMGCR Tclin 3-hydroxy-3-methylglutaryl-coenzyme A reductase (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HIF1A Tchem Hypoxia-inducible factor 1-alpha (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HDAC6 Tclin Histone deacetylase 6 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HRH1 Tclin Histamine H1 receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SLC6A3 Tclin Sodium-dependent dopamine transporter (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SLC6A4 Tclin Sodium-dependent serotonin transporter (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SIGMAR1 Tclin Sigma non-opioid intracellular receptor 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PTGS1 Tclin Prostaglandin G/H synthase 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CA2 Tclin Carbonic anhydrase 2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
DRD3 Tclin D(3) dopamine receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
KDR Tclin Vascular endothelial growth factor receptor 2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CHRM3 Tclin Muscarinic acetylcholine receptor M3 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CHRM4 Tclin Muscarinic acetylcholine receptor M4 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ADRA2B Tclin Alpha-2B adrenergic receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ADRA2C Tclin Alpha-2C adrenergic receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HTR2A Tclin 5-hydroxytryptamine receptor 2A (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ADORA2A Tclin Adenosine receptor A2a (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ACHE Tclin Acetylcholinesterase (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ADRA1B Tclin Alpha-1B adrenergic receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ADRA1A Tclin Alpha-1A adrenergic receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
AR Tclin Androgen receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
MAOA Tclin Amine oxidase [flavin-containing] A (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
AKR1B1 Tclin Aldose reductase (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ADORA1 Tclin Adenosine receptor A1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HTR1A Tclin 5-hydroxytryptamine receptor 1A (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ADORA3 Tchem Adenosine receptor A3 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HTR6 Tchem 5-hydroxytryptamine receptor 6 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HTR2B Tclin 5-hydroxytryptamine receptor 2B (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
F2 Tclin Prothrombin (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
EDNRA Tclin Endothelin-1 receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
KCNH2 Tclin Potassium voltage-gated channel subfamily H member 2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
OPRD1 Tclin Delta-type opioid receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
OPRK1 Tclin Kappa-type opioid receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
OPRM1 Tclin Mu-type opioid receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
NOS2 Tchem Nitric oxide synthase, inducible (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
TACR1 Tclin Substance-P receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
NOS1 Tchem Nitric oxide synthase, brain (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PDE5A Tclin Phosphodiesterase 5A (5113 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EGFR Tclin Epidermal growth factor receptor erbB1 (33727 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
F2 Tclin Thrombin (11687 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA2 Tclin Carbonic anhydrase II (17698 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ESR1 Tclin Estrogen receptor alpha (17718 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HMGCR Tclin HMG-CoA reductase (2475 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NR3C1 Tclin Glucocorticoid receptor (14987 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
INSR Tclin Insulin receptor (5558 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PGR Tclin Progesterone receptor (8562 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRB2 Tclin Beta-2 adrenergic receptor (11824 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM2 Tclin Muscarinic acetylcholine receptor M2 (10671 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRB1 Tclin Beta-1 adrenergic receptor (6630 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR1A Tclin Serotonin 1a (5-HT1a) receptor (14969 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA2A Tclin Alpha-2a adrenergic receptor (9450 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AR Tclin Androgen Receptor (11781 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ACE Tclin Angiotensin-converting enzyme (1423 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD2 Tclin Dopamine D2 receptor (23596 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MAOA Tclin Monoamine oxidase A (11911 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CNR1 Tclin Cannabinoid CB1 receptor (20913 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD1 Tclin Dopamine D1 receptor (9720 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD4 Tchem Dopamine D4 receptor (7907 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ACHE Tclin Acetylcholinesterase (18204 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A2 Tclin Norepinephrine transporter (10102 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HRH2 Tclin Histamine H2 receptor (5428 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1D Tclin Alpha-1d adrenergic receptor (4171 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR1B Tclin Serotonin 1b (5-HT1b) receptor (2801 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR2A Tclin Serotonin 2a (5-HT2a) receptor (14758 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR2C Tclin Serotonin 2c (5-HT2c) receptor (11471 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADORA1 Tclin Adenosine A1 receptor (17603 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CALCR Tclin Calcitonin receptor (2215 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A4 Tclin Serotonin transporter (12625 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1A Tclin Alpha-1a adrenergic receptor (8359 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS2 Tclin Cyclooxygenase-2 (13999 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HRH1 Tclin Histamine H1 receptor (7573 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1B Tclin Alpha-1b adrenergic receptor (2912 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRM1 Tclin Mu opioid receptor (19785 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD3 Tclin Dopamine D3 receptor (14368 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AVPR1A Tclin Vasopressin V1a receptor (5412 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRD1 Tclin Delta opioid receptor (15096 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRK1 Tclin Kappa opioid receptor (16155 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A3 Tclin Dopamine transporter (10535 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KCNH2 Tclin HERG (29587 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR4 Tclin Serotonin 4 (5-HT4) receptor (2068 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PDE3A Tclin Phosphodiesterase 3A (3309 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ESR2 Tclin Estrogen receptor beta (9272 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYSLTR1 Tclin Cysteinyl leukotriene receptor 1 (2118 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ERBB2 Tclin Receptor protein-tyrosine kinase erbB-2 (7851 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM4 Tclin Muscarinic acetylcholine receptor M4 (6041 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Agtr2 Angiotensin II type 2 (AT-2) receptor (803 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mc4r Melanocortin receptor 4 (1205 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ltc4s Leukotriene C4 synthase (1 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Sigmar1 Sigma opioid receptor (160 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Npy1r Neuropeptide Y receptor type 1 (8 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cckar Cholecystokinin A receptor (90 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nos2 Nitric oxide synthase, inducible (3573 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mapk1 MAP kinase ERK2 (650 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mmp9 Matrix metalloproteinase 9 (38 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Luciferin 4-monooxygenase (66902 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FTL Ferritin light chain (43324 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Glra2 Glycine receptor (1745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

Pubchem Sid488180509
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488180509
IUPAC Name 4-phenylmethoxyphenol
INCHI InChI=1S/C13H12O2/c14-12-6-8-13(9-7-12)15-10-11-4-2-1-3-5-11/h1-9,14H,10H2
InChi Key VYQNWZOUAUKGHI-UHFFFAOYSA-N
Canonical SMILES C1=CC=C(C=C1)COC2=CC=C(C=C2)O
Isomeric SMILES C1=CC=C(C=C1)COC2=CC=C(C=C2)O
WGK Germany 2
RTECS SJ7700000
PubChem CID 7638
UN Number 2430
Molecular Weight 200.23
Beilstein 1958305
Reaxy-Rn 1958305

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

19 results found

Lot NumberCertificate TypeDateItem
G2403144Certificate of AnalysisApr 23, 2024 B100826
A2206918Certificate of AnalysisOct 12, 2023 B100826
A2206920Certificate of AnalysisOct 12, 2023 B100826
A2206916Certificate of AnalysisOct 12, 2023 B100826
I2103040Certificate of AnalysisJun 07, 2023 B100826
I2103039Certificate of AnalysisJun 07, 2023 B100826
I2103038Certificate of AnalysisJun 07, 2023 B100826
F23301066Certificate of AnalysisJun 02, 2023 B100826
F23301067Certificate of AnalysisJun 02, 2023 B100826
F2330427Certificate of AnalysisJun 02, 2023 B100826
F2330433Certificate of AnalysisJun 02, 2023 B100826
F2330443Certificate of AnalysisJun 02, 2023 B100826
F2330444Certificate of AnalysisJun 02, 2023 B100826
H2026047Certificate of AnalysisJun 17, 2022 B100826
H2026046Certificate of AnalysisJun 17, 2022 B100826
E2324091Certificate of AnalysisDec 17, 2021 B100826
C2308350Certificate of AnalysisDec 17, 2021 B100826
B2315202Certificate of AnalysisDec 17, 2021 B100826
B2306869Certificate of AnalysisDec 17, 2021 B100826

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Chemical and Physical Properties

SolubilitySlightly soluble in water. Soluble in alcohol, acetone, benzene, and diethyl ether.
Sensitivitylight sensitive
Melt Point(°C)117-122°C

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H319:Causes serious eye irritation

H317:May cause an allergic skin reaction

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P501:Dispose of contents/container to ...

P272:Contaminated work clothing should not be allowed out of the workplace.

P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

WGK Germany 2
RTECS SJ7700000
Reaxy-Rn 1958305
Merck Index 6248

Related Documents

Citations of This Product

1. Jia-Pei Guo, Fang-Jing Liu, Lei-Lei Bie, Xing-Gang Si, Yan-Hong Li, Ping Song, Nian Liu, Yun-Peng Zhao, Zai-Xing Huang, Jing-Pei Cao, Xian-Yong Wei.  (2022)  Selective cleavage of C–O bond in lignin and lignin model compounds over iron/nitrogen co-doped carbon supported Ni catalyst.  FUEL,  316  (123338).  [PMID:]

References

1. A K Bajaj,S C Gupta,A K Chatterjee.  (1992-08-01)  Hearing aid depigmentation..  Contact dermatitis,  27  ((2)): (126-127).  [PMID:1395624]
2. A B Lerner.  (1992-01-01)  The Seiji memorial lecture. Pigment stories: from vitiligo to melanomas and points in between..  Pigment cell research,    (19-21).  [PMID:1409420]
3. A K Bajaj,S C Gupta,A K Chatterjee.  (1991-01-01)  Contact depigmentation of the breast..  Contact dermatitis,  24  ((1)): (58-58).  [PMID:1842336]
4. W C Quevedo,T J Holstein,J Dyckman,J J Nordlund.  (1990-03-01)  Influence of depigmenting chemical agents on hair and skin color in yellow (pheomelanic) and black (eumelanic) mice..  Pigment cell research,  ((2)): (71-79).  [PMID:2385568]
5. N Haas.  (1988-05-13)  [Confetti-like dyschromia caused by a bleaching cream containing hydroquinone in racially pigmented patients]..  Medizinische Klinik (Munich, Germany : 1983),  83  ((11)): (385-386).  [PMID:3405155]
6. E Frenk.  (1986-01-01)  [Treatment of vitiligo]..  Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete,  37  ((1)): (1-5).  [PMID:3949507]
7. T Tezuka,M Saheki,S Kusuda,K Umemoto.  (1993-05-01)  Treatment of nonhairy melanocytic macules by dermabrasion and topical application of 5% hydroquinone monobenzyl ether cream..  Journal of the American Academy of Dermatology,  28  ((5 Pt 1)): (771-772).  [PMID:8496423]
8. A K Bajaj,S C Gupta,A K Chatterjee.  (1996-08-01)  Footwear depigmentation..  Contact dermatitis,  35  ((2)): (117-118).  [PMID:8917842]
9. C C Lyon,M H Beck.  (1998-10-15)  Contact hypersensitivity to monobenzyl ether of hydroquinone used to treat vitiligo..  Contact dermatitis,  39  ((3)): (132-133).  [PMID:9771988]
10. Markus A Lill,Fabienne Winiger,Angelo Vedani,Beat Ernst.  (2005-09-02)  Impact of induced fit on ligand binding to the androgen receptor: a multidimensional QSAR study to predict endocrine-disrupting effects of environmental chemicals..  Journal of medicinal chemistry,  48  ((18)): (5666-5674).  [PMID:16134935]
11. Behrooz Kasraee,Mohammad Reza Fallahi,Gholamreza Safaee Ardekani,Saeed Ebrahimi,Gholamreza Doroudchi,Gholamhossein R Omrani,Farhad Handjani,Mitra Amini,Nader Tanideh,Marzieh Haddadi,Mohammad Nikbakhsh,Saeedeh Jahanbani,Christian Tran,Olivier Sorg,Jean-Hilaire Saurat.  (2006-06-10)  Retinoic acid synergistically enhances the melanocytotoxic and depigmenting effects of monobenzylether of hydroquinone in black guinea pig skin..  Experimental dermatology,  15  ((7)): (509-514).  [PMID:16761959]
12. Torello Lotti,Francesca Prignano,Gionata Buggiani.  (2007-07-31)  New and experimental treatments of vitiligo and other hypomelanoses..  Dermatologic clinics,  25  ((3)): (393-400).  [PMID:17662905]
13. Vidhya Hariharan,Jared Klarquist,Mary J Reust,Amy Koshoffer,Mark D McKee,Raymond E Boissy,I Caroline Le Poole.  (2009-08-07)  Monobenzyl ether of hydroquinone and 4-tertiary butyl phenol activate markedly different physiological responses in melanocytes: relevance to skin depigmentation..  The Journal of investigative dermatology,  130  ((1)): (211-220).  [PMID:19657355]
14. Jasper G van den Boorn,Debby Konijnenberg,Esther P M Tjin,Daisy I Picavet,Nico J Meeuwenoord,Dmitri V Filippov,J P Wietze van der Veen,Jan D Bos,Cornelis J M Melief,Rosalie M Luiten.  (2010-05-26)  Effective melanoma immunotherapy in mice by the skin-depigmenting agent monobenzone and the adjuvants imiquimod and CpG..  PloS one,  ((5)): (e10626-e10626).  [PMID:20498710]
15. Jasper G van den Boorn,Daisy I Picavet,Paul F van Swieten,Henk A van Veen,Debby Konijnenberg,Peter A van Veelen,Toni van Capel,Esther C de Jong,Eric A Reits,Jan W Drijfhout,Jan D Bos,Cornelis J M Melief,Rosalie M Luiten.  (2011-02-18)  Skin-depigmenting agent monobenzone induces potent T-cell autoimmunity toward pigmented cells by tyrosinase haptenation and melanosome autophagy..  The Journal of investigative dermatology,  131  ((6)): (1240-1251).  [PMID:21326294]
16. Jürgen C Becker,David Schrama.  (2011-05-14)  Breaking immunological tolerance to melanocyte differentiation antigens by hypopigmenting agents: a new means for melanoma immunotherapy?.  The Journal of investigative dermatology,  131  ((6)): (1185-1187).  [PMID:21566576]
17. Zhichao Liu,Qiang Shi,Don Ding,Reagan Kelly,Hong Fang,Weida Tong.  (2011-12-24)  Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps)..  PLoS computational biology,  ((12)): (e1002310-e1002310).  [PMID:22194678]
18. Siavash Toosi,Seth J Orlow,Prashiela Manga.  (2012-06-15)  Vitiligo-inducing phenols activate the unfolded protein response in melanocytes resulting in upregulation of IL6 and IL8..  The Journal of investigative dermatology,  132  ((11)): (2601-2609).  [PMID:22696056]
19. Jonathan G Bonchak,Jonathan M Eby,Kristin A Willenborg,David Chrobak,Steven W Henning,Anna Krzywiec,Steven L Johnson,I Caroline Le Poole.  (2014-08-19)  Targeting melanocyte and melanoma stem cells by 8-hydroxy-2-dipropylaminotetralin..  Archives of biochemistry and biophysics,  563  (71-78).  [PMID:25132642]
20. L A Rheins,J J Nordlund.  (1986-02-01)  Modulation of the population density of identifiable epidermal Langerhans cells associated with enhancement or suppression of cutaneous immune reactivity..  Journal of immunology (Baltimore, Md. : 1950),  136  ((3)): (867-876).  [PMID:3079801]
21. A Catona,D Lanzer.  (1987-03-16)  Monobenzone, Superfade, vitiligo and confetti-like depigmentation..  The Medical journal of Australia,  146  ((6)): (320-321).  [PMID:3821640]
22. C Sanz de Galdeano,A Aguirre,R Zabala,J A Ratón,J L Díaz-Pérez.  (1993-07-01)  Achromic patch test from hydroquinone monobenzyl ether..  Contact dermatitis,  29  ((1)): (43-44).  [PMID:8365157]
23. A M Oakley.  (1996-05-01)  Rapid repigmentation after depigmentation therapy: vitiligo treated with monobenzyl ether of hydroquinone..  The Australasian journal of dermatology,  37  ((2)): (96-98).  [PMID:8687336]
24. T A Wee.  (1997-02-01)  A case report of extensive vitiligo..  Hawaii medical journal,  56  ((2)): (37-40).  [PMID:9063009]
25. K Urabe,Y Hori.  (1997-03-01)  Dyschromatosis..  Seminars in cutaneous medicine and surgery,  16  ((1)): (81-85).  [PMID:9125769]
26. K M AlGhamdi,A Kumar.  (2010-11-09)  Depigmentation therapies for normal skin in vitiligo universalis..  Journal of the European Academy of Dermatology and Venereology : JEADV,  25  ((7)): (749-757).  [PMID:21054565]
27. Jasper G van den Boorn,Cornelis J Melief,Rosalie M Luiten.  (2011-06-22)  Monobenzone-induced depigmentation: from enzymatic blockade to autoimmunity..  Pigment cell & melanoma research,  24  ((4)): (673-679).  [PMID:21689385]
28. Jia-Pei Guo, Fang-Jing Liu, Lei-Lei Bie, Xing-Gang Si, Yan-Hong Li, Ping Song, Nian Liu, Yun-Peng Zhao, Zai-Xing Huang, Jing-Pei Cao, Xian-Yong Wei.  (2022)  Selective cleavage of C–O bond in lignin and lignin model compounds over iron/nitrogen co-doped carbon supported Ni catalyst.  FUEL,  316  (123338).  [PMID:]

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