4-Bromo-N-(4-bromophenyl)-3-[[(phenylmethyl)amino]sulfonyl]benzamide - ≥98%(HPLC), high purity , CAS No.312756-74-4

  • ≥98%(HPLC)
Item Number
B137570
Grouped product items
SKUSizeAvailabilityPrice Qty
B137570-5mg
5mg
In stock
$58.90
B137570-25mg
25mg
In stock
$265.90
B137570-100mg
100mg
In stock
$444.90

High affinity RAD51 stimulator

Basic Description

SynonymsRS-1 | 312756-74-4 | 3-(benzylsulfamoyl)-4-bromo-N-(4-bromophenyl)benzamide | 4-Bromo-N-(4-bromophenyl)-3-[[(phenylmethyl)amino]sulfonyl]benzamide | 3-(N-Benzylsulfamoyl)-4-bromo-N-(4-bromophenyl)benzamide | RAD51-Stimulatory Compound-1, RS-1 | RS1 | 4-bromanyl-N-(4-br
Specifications & Purity≥98%(HPLC)
Biochemical and Physiological MechanismsRAD51-Stimulatory Compound-1, RS-1 is a cell-permeable sulfonamido-benzamide compound which acts as an allosteric effector of active human RAD51 filament structure and stimulates DNA binding and recombination activities of hRAD51 protein. RS-1 is shown to
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Associated Targets(Human)

PTH1R Tclin Parathyroid hormone receptor (47172 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GLP1R Tclin Glucagon-like peptide 1 receptor (111429 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TP53 Tchem Cellular tumor antigen p53 (48468 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HEK293 (82097 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HepG2 (196354 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SNCA Tchem Alpha-synuclein (10960 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SMAD3 Tchem Mothers against decapentaplegic homolog 3 (68039 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ATXN2 Tbio Ataxin-2 (54410 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RAD51 Tchem DNA repair protein RAD51 homolog 1 (504 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Cruzipain (33337 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mapt Microtubule-associated protein tau (6 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name 3-(benzylsulfamoyl)-4-bromo-N-(4-bromophenyl)benzamide
INCHI InChI=1S/C20H16Br2N2O3S/c21-16-7-9-17(10-8-16)24-20(25)15-6-11-18(22)19(12-15)28(26,27)23-13-14-4-2-1-3-5-14/h1-12,23H,13H2,(H,24,25)
InChi Key SWKAVEUTKGKHSR-UHFFFAOYSA-N
Canonical SMILES C1=CC=C(C=C1)CNS(=O)(=O)C2=C(C=CC(=C2)C(=O)NC3=CC=C(C=C3)Br)Br
Isomeric SMILES C1=CC=C(C=C1)CNS(=O)(=O)C2=C(C=CC(=C2)C(=O)NC3=CC=C(C=C3)Br)Br
WGK Germany 3
PubChem CID 1039737
Molecular Weight 524.23

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Certificate of Analysis(COA)

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1 results found

Lot NumberCertificate TypeDateItem
E2008028Certificate of AnalysisDec 13, 2023 B137570

Chemical and Physical Properties

SolubilitySoluble in DMSO (≥10 mg/ml), and ethanol.
SensitivityAir Sensitive,Moisture Sensitive,Heat Sensitive
Melt Point(°C)208 °C

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H319:Causes serious eye irritation

Precautionary Statements

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

WGK Germany 3

Related Documents

Solution Calculators