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4-Chloro-7-nitro-1,2,3-benzoxadiazole - 98%, high purity , CAS No.10199-89-0

14 Citations

≥98%

CAS#: 10199-89-0
Formula: C₆H₂CLN₃O₃
Molecular Weight: 199.55
Beilstein Registry Number: 614212
EC Number: 233-496-4
MDL number: MFCD00005808
PubChem CID: 25043
PubChem SID: 488182943

Item Number

C113202

Grouped product items
SKU	Size	Availability	Price
C113202-100mg	100mg	In stock	$14.90
C113202-200mg	200mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$26.90
C113202-250mg	250mg	In stock	$29.90
C113202-1g	1g	In stock	$98.90
C113202-5g	5g	In stock	$445.90

Amine-reactive, fluorogenic dye

View related series

Five-Membered Heterocyclic Compounds Oxadiazoles

Basic Description

Synonyms	NBD-Cl \| 4-Chloro-7-nitrobenzofurazan, BioReagent, suitable for fluorescence, >=97.0% (HPLC) \| CS-7530 \| DTXSID2064995 \| 1-Chloro-4-nitrobenzoxadiazole \| AC-24649 \| AKOS000121286 \| SY011187 \| : 4-Chloro-7-nitro-1,2,3-benzoxadiazole \| AM85450 \| SR-01000596
Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	Amine-reactive, fluorogenic dye. Forms green fluorescent adducts with aliphatic amines and thiols. Labels proteins, peptides, amino acids and other biomolecules.
Storage Temp	Store at 2-8°C,Argon charged
Shipped In	Wet ice
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description	4-Chloro-7-nitrobenzofurazan is a dye that forms highly fluorescent compounds upon reaction with amines or thiol compounds. This reagent is used to label peptides, proteins and other biomolecules. for HPLC Labeling

Associated Targets(Human)

GSTA2 Tbio Glutathione S-transferase A2 (0 Activities)

Discover Target: GSTA2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GSTA2 Tbio Glutathione S-transferase A2 (52 Activities)

Discover Target: GSTA2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

Pubchem Sid	488182943
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488182943
IUPAC Name	4-chloro-7-nitro-2,1,3-benzoxadiazole
INCHI	InChI=1S/C6H2ClN3O3/c7-3-1-2-4(10(11)12)6-5(3)8-13-9-6/h1-2H
InChi Key	IGHBXJSNZCFXNK-UHFFFAOYSA-N
Canonical SMILES	C1=C(C2=NON=C2C(=C1)Cl)[N+](=O)[O-]
Isomeric SMILES	C1=C(C2=NON=C2C(=C1)Cl)[N+](=O)[O-]
WGK Germany	3
RTECS	DF8002400
PubChem CID	25043
UN Number	2811
Molecular Weight	199.55
Beilstein	614212
Reaxy-Rn	614212

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

7 results found

Lot Number	Certificate Type	Date	Item
A2303111	Certificate of Analysis	Dec 08, 2022	C113202
A2303112	Certificate of Analysis	Dec 08, 2022	C113202
A2303114	Certificate of Analysis	Dec 08, 2022	C113202
A2303118	Certificate of Analysis	Dec 08, 2022	C113202
A2303120	Certificate of Analysis	Dec 08, 2022	C113202
A2303121	Certificate of Analysis	Dec 08, 2022	C113202
H2219133	Certificate of Analysis	Aug 24, 2022	C113202

Chemical and Physical Properties

Solubility	Soluble in methanol, DMSO, and CHCl3 (50 mg/ml).
Sensitivity	Moisture sensitive
Melt Point(°C)	97-99°C

Safety and Hazards(GHS)

Pictogram(s)	GHS06, GHS07
Signal	Danger
Hazard Statements	H301:Toxic if swallowed H302:Harmful if swallowed
Precautionary Statements	P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P301+P317:IF SWALLOWED: Get medical help.
WGK Germany	3
RTECS	DF8002400
Reaxy-Rn	614212

FAQs and Articles

FAQ

Diels–Alder Reaction

Categories: Technical articles

Tags:

Organic block Diels-Alder Reaction

Fluorescent Probes - Absorption and Fluorescence

Categories: Technical articles

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Fluorescence Fuorescent Probe Fluorescent dyes

Citations of This Product

1. Huan Li, Qiwei Wang, Lili Shi, Tao Li. (2023) Sensitively detecting endogenous homocysteine in human serum and cardiomyocytes with a specific fluorescent probe. ANALYST, (6): [PMID:37850493]
2. Yizhen Cheng, Jing Kang, Pengwei Yan, Jimin Shen, Zhonglin Chen, Xinwei Zhu, Qiang Tan, Linlu Shen, Shuyu Wang, Shaobin Wang. (2024) Surface oxygen vacancies prompted the formation of hydrated hydroxyl groups on ZnOx in enhancing interfacial catalytic ozonation. APPLIED CATALYSIS B-ENVIRONMENTAL, 341 (123325). [PMID:14603368]
3. Lijun Hu, Zhichao Ding, Fei Yan, Yi-Meng Du, Qianxiang Xiao, Hongqing Wang. (2023) Inhibition of superoxide radical diffusion by Van der Waals forces for boosting photocatalytic H2O2 production. APPLIED SURFACE SCIENCE, 638 (158135). [PMID:]
4. Bochui Zhao, Xian Xu, Binghua Li, Zhizun Qi, Jinan Huang, Ali Hu, Guiqi Wang, Xiaomin Liu. (2023) Target-site mutation and enhanced metabolism endow resistance to nicosulfuron in a Digitaria sanguinalis population. PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 194 (105488). [PMID:37532350]
5. Yang Guo, Gang Yu, Urs von Gunten, Yujue Wang. (2023) Evaluation of the role of superoxide radical as chain carrier for the formation of hydroxyl radical during ozonation. WATER RESEARCH, 242 (120158). [PMID:37329717]
6. Qian Yang, Jinlei Zhu, Xia Yang, Tian Wei, Min Lv, Yongfeng Li. (2023) Ile-1781-Leu Target Mutation and Non-Target-Site Mechanism Confer Resistance to Acetyl-CoA Carboxylase-Inhibiting Herbicides in Digitaria ciliaris var. chrysoblephara. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 71 (21): (7988–7995). [PMID:37191622]
7. Chen Wang, Huanran Liu, Peng Sun, Jingjing Cai, Mingxing Sun, Haijiao Xie, Guoqing Shen. (2023) A novel peroxymonosulfate activation process by single-atom iron catalyst from waste biomass for efficient singlet oxygen-mediated degradation of organic pollutants. JOURNAL OF HAZARDOUS MATERIALS, 453 (131333). [PMID:37060750]
8. Wei Qu, Zhuoyun Tang, Hailin Wen, Manhui Luo, Tao Zhong, Qiyu Lian, Lingling Hu, Shuanghong Tian, Chun He, Dong Shu. (2023) Electron Transfer Trade-offs in MOF-Derived Cobalt-Embedded Nitrogen-Doped Carbon Nanotubes Boost Catalytic Ozonation for Gaseous Sulfur-Containing VOC Elimination. ACS Catalysis, 13 (1): (692–705). [PMID:]
9. Qian Yang, Xia Yang, Jinlei Zhu, Tian Wei, Min Lv, Yongfeng Li. (2022) Metabolic Resistance to Acetyl-CoA Carboxylase-Inhibiting Herbicide Cyhalofop-Butyl in a Chinese Echinochloa crus-galli Population. Agronomy-Basel, 12 (11): (2724). [PMID:]
10. Qian Rao, Dandan Lv, Hui-qiang Li, Qin Long. (2022) Enhanced Degradation of 1-Hydroxy-1,1-Diphosphonoethane in Three-Dimensional Electro-Fenton Process Through Selection of Ag Nanostructure in Layered Double Hydroxides-Ag @Fe3O4 Particles. ENVIRONMENTAL ENGINEERING SCIENCE, 39 (7): (628-638). [PMID:]
11. Yang Guo, Jingfei Long, Jun Huang, Gang Yu, Yujue Wang. (2022) Can the commonly used quenching method really evaluate the role of reactive oxygen species in pollutant abatement during catalytic ozonation?. WATER RESEARCH, 215 (118275). [PMID:35305491]
12. Xinyi Cai, Jinyi Chen, Xiaofei Wang, Haitao Gao, Binghan Xiang, Liyao Dong. (2022) Mefenacet resistance in multiple herbicide-resistant Echinochloa crus-galli L. populations. PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 182 (105038). [PMID:35249656]
13. Huawei Niu, Xintong Mi, Xinting Hua, Yuanyuan Zhang, Yaping Zhai, Fangyuan Qin, Yong Ye, Yufen Zhao. (2022) A bifunctional fluorescent probe based on “AND logic” for the simultaneous recognition of H2S/HNO and its bioimaging applications. ANALYTICA CHIMICA ACTA, 1192 (339341). [PMID:35057948]
14. Ning Zhao, Minghao Jiang, Qi Li, Quan Gao, Jingxu Zhang, Min Liao, Haiqun Cao. (2021) Cyhalofop-butyl resistance conferred by a novel Trp-2027-Leu mutation of acetyl-CoA carboxylase and enhanced metabolism in Leptochloa chinensis. PEST MANAGEMENT SCIENCE, 78 (3): (1176-1186). [PMID:34822218]

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40. Huan Li, Qiwei Wang, Lili Shi, Tao Li. (2023) Sensitively detecting endogenous homocysteine in human serum and cardiomyocytes with a specific fluorescent probe. ANALYST, (6): [PMID:37850493]
41. Yizhen Cheng, Jing Kang, Pengwei Yan, Jimin Shen, Zhonglin Chen, Xinwei Zhu, Qiang Tan, Linlu Shen, Shuyu Wang, Shaobin Wang. (2024) Surface oxygen vacancies prompted the formation of hydrated hydroxyl groups on ZnOx in enhancing interfacial catalytic ozonation. APPLIED CATALYSIS B-ENVIRONMENTAL, 341 (123325). [PMID:14603368]
42. Lijun Hu, Zhichao Ding, Fei Yan, Yi-Meng Du, Qianxiang Xiao, Hongqing Wang. (2023) Inhibition of superoxide radical diffusion by Van der Waals forces for boosting photocatalytic H2O2 production. APPLIED SURFACE SCIENCE, 638 (158135). [PMID:]
43. Bochui Zhao, Xian Xu, Binghua Li, Zhizun Qi, Jinan Huang, Ali Hu, Guiqi Wang, Xiaomin Liu. (2023) Target-site mutation and enhanced metabolism endow resistance to nicosulfuron in a Digitaria sanguinalis population. PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 194 (105488). [PMID:37532350]
44. Yang Guo, Gang Yu, Urs von Gunten, Yujue Wang. (2023) Evaluation of the role of superoxide radical as chain carrier for the formation of hydroxyl radical during ozonation. WATER RESEARCH, 242 (120158). [PMID:37329717]
45. Qian Yang, Jinlei Zhu, Xia Yang, Tian Wei, Min Lv, Yongfeng Li. (2023) Ile-1781-Leu Target Mutation and Non-Target-Site Mechanism Confer Resistance to Acetyl-CoA Carboxylase-Inhibiting Herbicides in Digitaria ciliaris var. chrysoblephara. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 71 (21): (7988–7995). [PMID:37191622]
46. Chen Wang, Huanran Liu, Peng Sun, Jingjing Cai, Mingxing Sun, Haijiao Xie, Guoqing Shen. (2023) A novel peroxymonosulfate activation process by single-atom iron catalyst from waste biomass for efficient singlet oxygen-mediated degradation of organic pollutants. JOURNAL OF HAZARDOUS MATERIALS, 453 (131333). [PMID:37060750]
47. Wei Qu, Zhuoyun Tang, Hailin Wen, Manhui Luo, Tao Zhong, Qiyu Lian, Lingling Hu, Shuanghong Tian, Chun He, Dong Shu. (2023) Electron Transfer Trade-offs in MOF-Derived Cobalt-Embedded Nitrogen-Doped Carbon Nanotubes Boost Catalytic Ozonation for Gaseous Sulfur-Containing VOC Elimination. ACS Catalysis, 13 (1): (692–705). [PMID:]
48. Qian Yang, Xia Yang, Jinlei Zhu, Tian Wei, Min Lv, Yongfeng Li. (2022) Metabolic Resistance to Acetyl-CoA Carboxylase-Inhibiting Herbicide Cyhalofop-Butyl in a Chinese Echinochloa crus-galli Population. Agronomy-Basel, 12 (11): (2724). [PMID:]
49. Qian Rao, Dandan Lv, Hui-qiang Li, Qin Long. (2022) Enhanced Degradation of 1-Hydroxy-1,1-Diphosphonoethane in Three-Dimensional Electro-Fenton Process Through Selection of Ag Nanostructure in Layered Double Hydroxides-Ag @Fe3O4 Particles. ENVIRONMENTAL ENGINEERING SCIENCE, 39 (7): (628-638). [PMID:]
50. Yang Guo, Jingfei Long, Jun Huang, Gang Yu, Yujue Wang. (2022) Can the commonly used quenching method really evaluate the role of reactive oxygen species in pollutant abatement during catalytic ozonation?. WATER RESEARCH, 215 (118275). [PMID:35305491]
51. Xinyi Cai, Jinyi Chen, Xiaofei Wang, Haitao Gao, Binghan Xiang, Liyao Dong. (2022) Mefenacet resistance in multiple herbicide-resistant Echinochloa crus-galli L. populations. PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 182 (105038). [PMID:35249656]
52. Huawei Niu, Xintong Mi, Xinting Hua, Yuanyuan Zhang, Yaping Zhai, Fangyuan Qin, Yong Ye, Yufen Zhao. (2022) A bifunctional fluorescent probe based on “AND logic” for the simultaneous recognition of H2S/HNO and its bioimaging applications. ANALYTICA CHIMICA ACTA, 1192 (339341). [PMID:35057948]
53. Ning Zhao, Minghao Jiang, Qi Li, Quan Gao, Jingxu Zhang, Min Liao, Haiqun Cao. (2021) Cyhalofop-butyl resistance conferred by a novel Trp-2027-Leu mutation of acetyl-CoA carboxylase and enhanced metabolism in Leptochloa chinensis. PEST MANAGEMENT SCIENCE, 78 (3): (1176-1186). [PMID:34822218]

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