Grouped product items

SKU

Size

Availability

Price

Qty

C122655-5g

In stock

$15.90

C122655-10g

10g

Available within 4-8 weeks(?)

$27.90

C122655-25g

25g

In stock

$42.90

C122655-100g

100g

In stock

$153.90

C122655-500g

500g

Available within 8-12 weeks(?)

$692.90

Basic Description

Synonyms	NCI-C03292 \| 1,2-benzenediamine,-chloro-;1,2-Diamino-4-chlorobenzene;2-Amino-4-chloroaniline;4-Chloro-o-phenylenediamine \| p-Chloro-o-phenylenediamine \| C-(2-TRIFLUOROMETHYL-PYRIDIN-4-YL)-METHYLAMINE \| NCGC00260529-01 \| 2-AMINO-5-CHLOROANILINE \| AM2006076
Specifications & Purity	≥97%
Storage Temp	Argon charged
Shipped In	Normal
Product Description	Undergoes cyclizations and cyclocondensations to form benzimidazoles.

Associated Targets(Human)

CYP3A4 Tclin Cytochrome P450 3A4 (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ESR1 Tclin Estrogen receptor (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NR3C1 Tclin Glucocorticoid receptor (0 Activities)

Discover Target: NR3C1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

RUNX1 Tbio Runt-related transcription factor 1 (0 Activities)

Discover Target: RUNX1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

RORC Tchem Nuclear receptor ROR-gamma (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SMN1 Tchem Survival motor neuron protein (0 Activities)

Discover Target: SMN1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

RXRA Tclin Retinoic acid receptor RXR-alpha (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TSHR Tclin Thyrotropin receptor (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ALOX15 Tchem Arachidonate 15-lipoxygenase (0 Activities)

Discover Target: ALOX15

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NR1H4 Tclin Bile acid receptor (0 Activities)

Discover Target: NR1H4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NR1I2 Tchem Nuclear receptor subfamily 1 group I member 2 (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

AHR Tclin Aryl hydrocarbon receptor (0 Activities)

Discover Target: AHR

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

AR Tclin Androgen receptor (0 Activities)

Discover Target: AR

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ALDH1A1 Tchem Retinal dehydrogenase 1 (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

THRB Tclin Thyroid hormone receptor beta (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KCNH2 Tclin Potassium voltage-gated channel subfamily H member 2 (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PPARG Tclin Peroxisome proliferator-activated receptor gamma (0 Activities)

Discover Target: PPARG

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NFE2L2 Tchem Nuclear factor erythroid 2-related factor 2 (0 Activities)

Discover Target: NFE2L2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ESR1 Tclin Estrogen receptor alpha (17718 Activities)

Discover Target: ESR1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

NR3C1 Tclin Glucocorticoid receptor (14987 Activities)

Discover Target: NR3C1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

AR Tclin Androgen Receptor (11781 Activities)

Discover Target: AR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TSHR Tclin Thyroid stimulating hormone receptor (29986 Activities)

Discover Target: TSHR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PPARG Tclin Peroxisome proliferator-activated receptor gamma (15191 Activities)

Discover Target: PPARG

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

KCNH2 Tclin HERG (29587 Activities)

Discover Target: KCNH2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

THRB Tclin Thyroid hormone receptor beta-1 (7926 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

RXRA Tclin Retinoid X receptor alpha (3637 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

AHR Tclin Aryl hydrocarbon receptor (1071 Activities)

Discover Target: AHR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)

Discover Target: ALDH1A1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

NR1H4 Tclin Bile acid receptor FXR (6228 Activities)

Discover Target: NR1H4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ALOX15 Tchem Arachidonate 15-lipoxygenase (7108 Activities)

Discover Target: ALOX15

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)

Discover Target: CYP3A4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Lymphoblastoid cell (5959 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)

Discover Target: TDP1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SMN1 Tchem Survival motor neuron protein (34246 Activities)

Discover Target: SMN1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Mus musculus (284745 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Luciferin 4-monooxygenase (66902 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)

Discover Target: Nfe2l2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Rorc Nuclear receptor ROR-gamma (89407 Activities)

Discover Target: Rorc

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Nr1i2 Nuclear receptor subfamily 1 group I member 2 (14 Activities)

Discover Target: Nr1i2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	4-chlorobenzene-1,2-diamine
INCHI	InChI=1S/C6H7ClN2/c7-4-1-2-5(8)6(9)3-4/h1-3H,8-9H2
InChi Key	BXIXXXYDDJVHDL-UHFFFAOYSA-N
Canonical SMILES	C1=CC(=C(C=C1Cl)N)N
Isomeric SMILES	C1=CC(=C(C=C1Cl)N)N
WGK Germany	3
RTECS	SS8850000
PubChem CID	7263
UN Number	3143
Packing Group	I
Molecular Weight	142.59
Beilstein	508472
Reaxy-Rn	508472

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

12 results found

Lot Number	Certificate Type	Date	Item
C2323547	Certificate of Analysis	Mar 06, 2023	C122655
C2323550	Certificate of Analysis	Mar 06, 2023	C122655
C2323571	Certificate of Analysis	Mar 06, 2023	C122655
C2323574	Certificate of Analysis	Mar 06, 2023	C122655
C2323641	Certificate of Analysis	Mar 06, 2023	C122655
C2323642	Certificate of Analysis	Mar 06, 2023	C122655
F23061398	Certificate of Analysis	Mar 06, 2023	C122655
G2308178	Certificate of Analysis	Mar 06, 2023	C122655
F23061330	Certificate of Analysis	Jun 11, 2022	C122655
G2220483	Certificate of Analysis	Jun 11, 2022	C122655
G2220484	Certificate of Analysis	Jun 11, 2022	C122655
G2220485	Certificate of Analysis	Jun 11, 2022	C122655

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Chemical and Physical Properties

Solubility	Slightly soluble in water; Soluble in Benzene; Very slightly soluble in Ether,Ethanol
Sensitivity	air sensitive
Melt Point(°C)	70-73 °C

Safety and Hazards(GHS)

Pictogram(s)	GHS08, GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H351:Suspected of causing cancer H302:Harmful if swallowed
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P318:if exposed or concerned, get medical advice. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
WGK Germany	3
RTECS	SS8850000
Reaxy-Rn	508472
Class	6.1

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Shouying Wu, Linping Zhang, Jianing Fan, Wei Wu, Bolin Ji, Xueling Feng, Bijia Wang, Yimeng Ma, Yi Zhong, Hong Xu, Zhiping Mao. (2023) Iron(III) complexes promote hydrogen peroxide activation for efficient degradation of dyeing wastewater. COLORATION TECHNOLOGY, (1): [PMID:10648423] [10.1111/cote.12727]
2. Zhang Luping, Tu Xuewei, Han Weihang, Chen Liangchen, Chen Yutong, Zheng Hui. (2023) The Efficient CO2 Fixation Catalyzed by Fe-Based Catalyst for Synthesizing Benzimidazoles. CATALYSIS LETTERS, 153 (11): (3383-3391). [PMID:] [10.1007/s10562-022-04220-y]

References

1. L Soler-Niedziela,X Shi,J Nath,T Ong. (1991-01-01) Studies on three structurally related phenylenediamines with the mouse micronucleus assay system.. Mutation research, 259 ((1)): (43-48). [PMID:1703280]
2. . (1982-04-01) 4-Chloro-ortho-phenylenediamine and 4-chloro-meta-phenylenediamine.. IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans, 27 (81-89). [PMID:6955270]
3. A F McFee, P P Jauhar, K W Lowe, J T MacGregor, C M Wehr,. (1989-01-01) Assays of three carcinogen/non-carcinogen chemical pairs for in vivo induction of chromosome aberrations, sister chromatid exchanges and micronuclei.. Environmental and molecular mutagenesis, 14 ((4)): ( 207-220 ). [PMID:2583129]
4. W Suter,F Staedtler,F Poetter-Locher,T Swingler,L Wilson. (1998-06-19) 4-Chloro-o-phenylenediamine: a 26-week oral (in feed) mutagenicity study in Big Blue mice.. Mutation research, 414 ((1-3)): (149-156). [PMID:9630584]
5. Hiroshi Suzuki,Naohiro Ikeda,Kazuo Kobayashi,Yukari Terashima,Yasushi Shimada,Takayoshi Suzuki,Toshiyuki Hagiwara,Shigeki Hatakeyama,Koko Nagaoka,Junichi Yoshida,Yukiko Saito,Jin Tanaka,Makoto Hayashi. (2005-05-19) Evaluation of liver and peripheral blood micronucleus assays with 9 chemicals using young rats. A study by the Collaborative Study Group for the Micronucleus Test (CSGMT)/Japanese Environmental Mutagen Society (JEMS)-Mammalian Mutagenicity Study Group (MMS).. Mutation research, 583 ((2)): (133-145). [PMID:15899588]
6. Ilaria Massarelli,Marcello Imbriani,Alessio Coi,Marilena Saraceno,Niccolò Carli,Anna Maria Bianucci. (2009-03-11) Development of QSAR models for predicting hepatocarcinogenic toxicity of chemicals.. European journal of medicinal chemistry, 44 ((9)): (3658-3664). [PMID:19272677]
7. . (2011-08-19) 4-Chloro-o-phenylenediamine.. Report on carcinogens : carcinogen profiles, 12 (101-102). [PMID:21850148]
8. Dalia M S A Salem,Mohammed A E Sallam,Trevena N M A Youssef. (2019-03-18) Synthesis of compounds having antimicrobial activity from alginate.. Bioorganic chemistry, 87 (103-111). [PMID:30878809]
9. . (2004-08-24) 4-Chloro-o-phenylenediamine.. Report on carcinogens : carcinogen profiles, 10 (59-59). [PMID:15320323]
10. . (2004-01-01) 4-Chloro-o-phenylenediamine.. Report on carcinogens : carcinogen profiles, 11 (III58-III59). [PMID:21089830]
11. Shouying Wu, Linping Zhang, Jianing Fan, Wei Wu, Bolin Ji, Xueling Feng, Bijia Wang, Yimeng Ma, Yi Zhong, Hong Xu, Zhiping Mao. (2023) Iron(III) complexes promote hydrogen peroxide activation for efficient degradation of dyeing wastewater. COLORATION TECHNOLOGY, (1): [PMID:10648423] [10.1111/cote.12727]
12. Zhang Luping, Tu Xuewei, Han Weihang, Chen Liangchen, Chen Yutong, Zheng Hui. (2023) The Efficient CO2 Fixation Catalyzed by Fe-Based Catalyst for Synthesizing Benzimidazoles. CATALYSIS LETTERS, 153 (11): (3383-3391). [PMID:] [10.1007/s10562-022-04220-y]

Solution Calculators

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4-Chloro-o-phenylenediamine - 97%, high purity , CAS No.95-83-0

Basic Description

Associated Targets(Human)

Associated Targets(non-human)

Mechanisms of Action

Names and Identifiers

Certificates

Certificate of Analysis(COA)

Show more⌵

Chemical and Physical Properties

Safety and Hazards(GHS)

Related Documents

Citations of This Product

References

Solution Calculators

Molarity Calculator

Dilution Calculator

Reconstitution Calculator