Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
SKU | Size | Availability | Price | Qty |
---|---|---|---|---|
H104510-1g | 1g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $9.90 | |
H104510-5g | 5g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $19.90 | |
H104510-25g | 25g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $39.90 | |
H104510-100g | 100g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $63.90 | |
H104510-250g | 250g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $79.90 | |
H104510-500g | 500g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $99.90 |
Membrane permeable superoxide scavenger. SOD mimetic.
Synonyms | 4-Oxypiperidol|4-Hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl|4-hydroxy-2,2,6,6-tetramethyl piperidinyloxy|4-hydroxy-2,2,6,6-tetramethyl-piperidinooxy|1-Piperidinyloxy, 4-hydroxy-2,2,6,6-tetramethyl-|4-Hydroxy-TEMPO, free radical|MBM-02|U78ZX2F65X|2,2,6,6 |
---|---|
Specifications & Purity | ≥98% |
Biochemical and Physiological Mechanisms | Membrane permeable superoxide scavenger. SOD simulation. Reduce inflammation caused by superoxide anions and peroxynitrite. Reduce oxidative stress. |
Storage Temp | Store at 2-8°C,Argon charged |
Shipped In | Wet ice |
Note | 1g/5g/25g 售完停产 Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | TEMPOL is a superoxide dismutase mimetic that belongs to a class of non-thiol-containing radiation protectors, and has the ability to permeate the membrane. In the presence of TEMPOL, cerebral vessel remodeling is blocked and collagen IV mRNA expression levels are elevated in normotensive and hypertensive rat studies. TEMPOL has been shown to restore the oxidative stress and cardiac dysfunction induced by TNF-α and in PC-12 cells has revealed neuroprotective effects. Additionally, it has shown to decrease blood pressure and sympathetic nerve activity in DOCA-salt rat studies. product description: 4-Hydroxy-TEMPO is a 4-substituted 2,2,6,6-tetramethylpiperidyl-1-oxy (TEMPO) derivative. It is a low-molecular weight compound and has been proposed as superoxide dismutase mimic. |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Isomeric SMILES | CC1(CC(CC(N1[O])(C)C)O)C |
---|---|
WGK Germany | 1 |
RTECS | TN8991000 |
PubChem CID | 137994 |
Molecular Weight | 172.24 |
Beilstein | 1422990 |
Reaxy-Rn | 11328213 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
H2405231 | Certificate of Analysis | Jul 09, 2024 | H104510 |
H2405232 | Certificate of Analysis | Jul 09, 2024 | H104510 |
H2405238 | Certificate of Analysis | Jul 09, 2024 | H104510 |
A2410057 | Certificate of Analysis | Aug 01, 2022 | H104510 |
C2418077 | Certificate of Analysis | Aug 01, 2022 | H104510 |
C2418080 | Certificate of Analysis | Aug 01, 2022 | H104510 |
I2203235 | Certificate of Analysis | Aug 01, 2022 | H104510 |
I2203236 | Certificate of Analysis | Aug 01, 2022 | H104510 |
I2203237 | Certificate of Analysis | Aug 01, 2022 | H104510 |
I2203238 | Certificate of Analysis | Aug 01, 2022 | H104510 |
I2203239 | Certificate of Analysis | Aug 01, 2022 | H104510 |
I2205238 | Certificate of Analysis | Aug 01, 2022 | H104510 |
I2308184 | Certificate of Analysis | Aug 01, 2022 | H104510 |
I2308185 | Certificate of Analysis | Aug 01, 2022 | H104510 |
F2209157 | Certificate of Analysis | Jul 28, 2021 | H104510 |
Solubility | Easily soluble in organic solvents such as ethanol and benzene, and easily soluble in water. |
---|---|
Sensitivity | light sensitive & Moisture sensitive |
Flash Point(°F) | 146℃ |
Flash Point(°C) | 146℃ |
Melt Point(°C) | 69-71°C |
Pictogram(s) | GHS07 |
---|---|
Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. |
WGK Germany | 1 |
RTECS | TN8991000 |
Reaxy-Rn | 11328213 |
Merck Index | 9141 |
Starting at $55.90