4-Hydroxybenzyl Alcohol - 97%, high purity , CAS No.623-05-2

  • ≥97%
Item Number
H107912
Grouped product items
SKUSizeAvailabilityPrice Qty
H107912-25g
25g
In stock
$23.90
H107912-100g
100g
In stock
$92.90
H107912-500g
500g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$414.90
View related series
alcohol Oxygenated compounds

Basic Description

SynonymsDTXSID8073920 | HMS3885O08 | 4-Hydroxybenzylalcohol | 4-Hydroxy-benzylalcohol | 4-hydroxybenzyl-alcohol | Benzenemethanol, 4-hydroxy- (9CI) | EC 210-768-0 | SCHEMBL62690 | STL284640 | EINECS 210-768-0 | p-Hydroxybenzyl alcohol | p-hydroxy-Benzyl alcohol |
Specifications & Purity≥97%
Storage TempStore at 2-8°C,Argon charged
Shipped InWet ice
Product Description

4-Hydroxybenzyl alcohol (HBA) is a phenolic compound found in Gastrodia elata. It is as an antioxidant and anti-asthmatic agent.

4-Hydroxybenzyl alcohol can be used as a precursor for the synthesis of:

• HBA-incorporated copolyoxalate (HPOX) nanoparticles as potential drug delivery system.

• Poly(4-hydroxybenzyl alcohol) by enzyme catalyzed reaction.

• 4-Hydroxybenzyl imidazole derivatives.

Associated Targets(Human)

MT-CO2 Tchem Cytochrome c oxidase subunit 2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GRB2 Tchem Growth factor receptor-bound protein 2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CRK Tchem Adapter molecule crk (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ALDH5A1 Tclin Succinate-semialdehyde dehydrogenase, mitochondrial (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
FYN Tclin Tyrosine-protein kinase Fyn (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
TOP1 Tclin DNA topoisomerase 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ABL1 Tclin Tyrosine-protein kinase ABL1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ABAT Tclin 4-aminobutyrate aminotransferase, mitochondrial (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ABL1 Tclin Tyrosine-protein kinase ABL (18331 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TOP1 Tclin DNA topoisomerase I (7553 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TYR Tclin Tyrosinase (717 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ABAT Tclin Gamma-amino-N-butyrate transaminase (140 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALDH5A1 Tclin Succinate semialdehyde dehydrogenase (19 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FYN Tclin Tyrosine-protein kinase FYN (5308 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HT-29 (80576 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RKO (1376 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SGC-7901 (2773 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KB (17409 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CRK Tchem Proto-oncogene C-crk (18 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MT-CO2 Tchem Cytochrome c oxidase subunit 2 (250 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HGC-27 (1452 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Grb2 Growth factor receptor-bound protein 2 (49 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RAW264.7 (28094 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
B16-F10 (4610 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 4-(hydroxymethyl)phenol
INCHI InChI=1S/C7H8O2/c8-5-6-1-3-7(9)4-2-6/h1-4,8-9H,5H2
InChi Key BVJSUAQZOZWCKN-UHFFFAOYSA-N
Canonical SMILES C1=CC(=CC=C1CO)O
Isomeric SMILES C1=CC(=CC=C1CO)O
WGK Germany 3
PubChem CID 125
Molecular Weight 124.14
Beilstein 1858967
Reaxy-Rn 1858967

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

11 results found

Lot NumberCertificate TypeDateItem
F2404067Certificate of AnalysisJun 15, 2024 H107912
I2320224Certificate of AnalysisSep 04, 2023 H107912
I2320249Certificate of AnalysisSep 04, 2023 H107912
I2320250Certificate of AnalysisSep 04, 2023 H107912
I2320251Certificate of AnalysisSep 04, 2023 H107912
I2320252Certificate of AnalysisSep 04, 2023 H107912
F1806090Certificate of AnalysisApr 25, 2022 H107912
C23101237Certificate of AnalysisNov 22, 2021 H107912
E2322636Certificate of AnalysisNov 22, 2021 H107912
E2323058Certificate of AnalysisNov 22, 2021 H107912
I2308192Certificate of AnalysisNov 22, 2021 H107912

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Chemical and Physical Properties

SolubilitySoluble in water (6.7 mg/ml at 20°C), dioxane (100 mg/ml), 1N NaOH (50 mg/ml), DMSO, and methanol.
SensitivityAir & Light & Heat sensitive
Boil Point(°C)251-253°C
Melt Point(°C)114-122°C

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 3
Reaxy-Rn 1858967

Related Documents

Citations of This Product

1. Zixin Xie, Xihong Zu, Jinxin Lin, Xueqing Qiu, Tengda Liang, Liheng Chen.  (2023)  A high-performance lignin flow fuel cell based on self-generating electricity of lignin at low temperature via a privileged structure and redox chemistry.  GREEN CHEMISTRY,      [PMID:] [10.1039/D3GC04428A]
2. Xingjie Guo, Peng Hong, Lu Yao, Xudong Liu, Zhicheng Jiang, Bi Shi.  (2023)  Catalytic hydrogenation of lignin-derived aldehydes over bimetallic PdNi/hydrotalcite catalyst under mild conditions.  FUEL,  353  (129231).  [PMID:] [10.1016/j.fuel.2023.129231]
3. Zhenyu Li, Enhui Du, Panpan Hao, Liyuan Huai, Yang Zhong, Soliman I. El-Hout, Chunlin Chen, Jian Zhang.  (2023)  Diluted oxygen realizes high productivity of 2,5-Furandicarboxylic acid under ambient temperature.  CATALYSIS TODAY,  423  (114277).  [PMID:] [10.1016/j.cattod.2023.114277]
4. Hongjie Zhang, Weijian Chen, Jing Wang, Wenxiang Du, Bibo Wang, Lei Song, Yuan Hu, Xiaopeng Ma.  (2023)  A novel ROS-activable self-immolative prodrug for tumor-specific amplification of oxidative stress and enhancing chemotherapy of mitoxantrone.  BIOMATERIALS,  293  (121954).  [PMID:36538847] [10.1016/j.biomaterials.2022.121954]
5. Peng Xie, Wang Zhang, Wugao Wu, Zhuanglin Shen, Mingliang Wang, Yuxiao Lai, Yantao Chen, Zhongfan Jia.  (2022)  Phenoxyl mediators improve enzymatic degradation of organic pollutants: Effect and mechanism.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  215  (606).  [PMID:35750102] [10.1016/j.ijbiomac.2022.06.124]
6. Yue Wei, Si Wu, Zhenqi Liu, Jingsheng Niu, Ya Zhou, Jinsong Ren, Xiaogang Qu.  (2022)  Tumor associated macrophages reprogrammed by targeted bifunctional bioorthogonal nanozymes for enhanced tumor immunotherapy.  Materials Today,  56  (16).  [PMID:] [10.1016/j.mattod.2022.01.024]
7. Li Luo, Guangchao Zang, Boyan Liu, Xian Qin, Yuchan Zhang, Yidan Chen, Haijun Zhang, Wei Wu, Guixue Wang.  (2021)  Bioengineering CXCR4-overexpressing cell membrane functionalized ROS-responsive nanotherapeutics for targeting cerebral ischemia-reperfusion injury.  Theranostics,  11  (16): ( 8043–8056).  [PMID:34335979] [10.7150/thno.60785]
8. Shouhua Su, Juan Wang, Chao Li, Jinfeng Yuan, Zhicheng Pan, Mingwang Pan.  (2021)  Short-Branched Fluorinated Polyurethane Coating Exhibiting Good Comprehensive Performance and Potential UV Degradation in Leather Waterproofing Modification.  Coatings,  11  (4): (395).  [PMID:] [10.3390/coatings11040395]
9. Peng Zeng, Wei-De Zhang.  (2021)  Photocatalytic hydrogen evolution over a nickel complex anchoring to thiophene embedded g-C3N4.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,  596  (75).  [PMID:33838327] [10.1016/j.jcis.2021.03.080]
10. Yin Hua, Hu Tiandong, Zhuang Yibin, Liu Tao.  (2020)  Metabolic engineering of Saccharomyces cerevisiae for high-level production of gastrodin from glucose.  Microbial Cell Factories,  19  (1): (1-12).  [PMID:33243241] [10.1186/s12934-020-01476-0]
11. Limin Li, Bin Hao, Yulong Zhang, Shen Ji, Guixin Chou.  (2020)  Metabolite Profiling and Distribution of Militarine in Rats Using UPLC-Q-TOF-MS/MS.  MOLECULES,  25  (5): (1082).  [PMID:32121087] [10.3390/molecules25051082]
12. Yun-Xiao Zhang, Peng Zeng, Yu-Xiang Yu, Wei-De Zhang.  (2020)  Integration of nickel complex as a cocatalyst onto in-plane benzene ring-incorporated graphitic carbon nitride nanosheets for efficient photocatalytic hydrogen evolution.  CHEMICAL ENGINEERING JOURNAL,  381  (122635).  [PMID:] [10.1016/j.cej.2019.122635]
13. Dong Shihao, Wen Ping, Zhang Qi, Li Xinyu, Tan Ken, Nieh James.  (2017)  Resisting majesty: Apis cerana, has lower antennal sensitivity and decreased attraction to queen mandibular pheromone than Apis mellifera.  Scientific Reports,  (1): (1-10).  [PMID:28294146] [10.1038/srep44640]
14. Yanfen Bai, Hua Yin, Huiping Bi, Yibin Zhuang, Tao Liu, Yanhe Ma.  (2016)  De novo biosynthesis of Gastrodin in Escherichia coli.  METABOLIC ENGINEERING,  35  (138).  [PMID:26804288] [10.1016/j.ymben.2016.01.002]
15. Jingying Pan, Jie Fu, Shuguang Deng, Xiuyang Lu.  (2015)  Distribution coefficient of products from lignin oxidative degradation in organic-water systems.  FUEL PROCESSING TECHNOLOGY,  140  (262).  [PMID:] [10.1016/j.fuproc.2015.09.016]
16. Jingying Pan, Jie Fu, Xiuyang Lu.  (2015)  Microwave-Assisted Oxidative Degradation of Lignin Model Compounds with Metal Salts.  ENERGY & FUELS,  29  (7): (4503–4509).  [PMID:] [10.1021/acs.energyfuels.5b00735]

References

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35. Xingjie Guo, Peng Hong, Lu Yao, Xudong Liu, Zhicheng Jiang, Bi Shi.  (2023)  Catalytic hydrogenation of lignin-derived aldehydes over bimetallic PdNi/hydrotalcite catalyst under mild conditions.  FUEL,  353  (129231).  [PMID:] [10.1016/j.fuel.2023.129231]
36. Zhenyu Li, Enhui Du, Panpan Hao, Liyuan Huai, Yang Zhong, Soliman I. El-Hout, Chunlin Chen, Jian Zhang.  (2023)  Diluted oxygen realizes high productivity of 2,5-Furandicarboxylic acid under ambient temperature.  CATALYSIS TODAY,  423  (114277).  [PMID:] [10.1016/j.cattod.2023.114277]
37. Hongjie Zhang, Weijian Chen, Jing Wang, Wenxiang Du, Bibo Wang, Lei Song, Yuan Hu, Xiaopeng Ma.  (2023)  A novel ROS-activable self-immolative prodrug for tumor-specific amplification of oxidative stress and enhancing chemotherapy of mitoxantrone.  BIOMATERIALS,  293  (121954).  [PMID:36538847] [10.1016/j.biomaterials.2022.121954]
38. Peng Xie, Wang Zhang, Wugao Wu, Zhuanglin Shen, Mingliang Wang, Yuxiao Lai, Yantao Chen, Zhongfan Jia.  (2022)  Phenoxyl mediators improve enzymatic degradation of organic pollutants: Effect and mechanism.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  215  (606).  [PMID:35750102] [10.1016/j.ijbiomac.2022.06.124]
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Solution Calculators