Determine the necessary mass, volume, or concentration for preparing a solution.
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Basic Description
| Synonyms | 4-hydroxybenzyl alcohol | 623-05-2 | 4-(Hydroxymethyl)phenol | p-Hydroxybenzyl alcohol | p-Methylolphenol | 4-Methylolphenol | 4-Hydroxybenzenemethanol | Benzenemethanol, 4-hydroxy- | 4-Hydroxybenzylalcohol | p-(Hydroxymethyl)phenol | Benzyl alcohol, p-hydroxy- | Gastrodigenin |
|---|---|
| Specifications & Purity | 10mM in DMSO |
| Storage Temp | Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Product Description | 4-Hydroxybenzyl alcohol (HBA) is a phenolic compound found in Gastrodia elata. It is as an antioxidant and anti-asthmatic agent. 4-Hydroxybenzyl alcohol can be used as a precursor for the synthesis of: • HBA-incorporated copolyoxalate (HPOX) nanoparticles as potential drug delivery system. • Poly(4-hydroxybenzyl alcohol) by enzyme catalyzed reaction. • 4-Hydroxybenzyl imidazole derivatives. |
Associated Targets(Human)
ABL1 Tclin Tyrosine-protein kinase ABL (18331 Activities)
TOP1 Tclin DNA topoisomerase I (7553 Activities)
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TYR Tclin Tyrosinase (717 Activities)
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ABAT Tclin Gamma-amino-N-butyrate transaminase (140 Activities)
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ALDH5A1 Tclin Succinate semialdehyde dehydrogenase (19 Activities)
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FYN Tclin Tyrosine-protein kinase FYN (5308 Activities)
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HT-29 (80576 Activities)
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RKO (1376 Activities)
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SGC-7901 (2773 Activities)
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KB (17409 Activities)
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CRK Tchem Proto-oncogene C-crk (18 Activities)
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MT-CO2 Tchem Cytochrome c oxidase subunit 2 (250 Activities)
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HGC-27 (1452 Activities)
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Associated Targets(non-human)
Grb2 Growth factor receptor-bound protein 2 (49 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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RAW264.7 (28094 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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B16-F10 (4610 Activities)
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Mechanisms of Action
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Names and Identifiers
| IUPAC Name | 4-(hydroxymethyl)phenol |
|---|---|
| INCHI | InChI=1S/C7H8O2/c8-5-6-1-3-7(9)4-2-6/h1-4,8-9H,5H2 |
| InChi Key | BVJSUAQZOZWCKN-UHFFFAOYSA-N |
| Canonical SMILES | C1=CC(=CC=C1CO)O |
| Isomeric SMILES | C1=CC(=CC=C1CO)O |
| WGK Germany | 3 |
| PubChem CID | 125 |
| Molecular Weight | 124.14 |
| Beilstein | 1858967 |
| Reaxy-Rn | 1858967 |
Certificates
Certificate of Analysis(COA)
Enter Lot Number to search for COA:
Chemical and Physical Properties
| Sensitivity | Air & Light & Heat sensitive |
|---|---|
| Boil Point(°C) | 251-253°C |
| Melt Point(°C) | 114-122°C |
Safety and Hazards(GHS)
| Pictogram(s) | GHS07 |
|---|---|
| Signal | Warning |
| Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation |
| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
| WGK Germany | 3 |
| Reaxy-Rn | 1858967 |
Related Documents
Citations of This Product
| 1. Zixin Xie, Xihong Zu, Jinxin Lin, Xueqing Qiu, Tengda Liang, Liheng Chen. (2023) A high-performance lignin flow fuel cell based on self-generating electricity of lignin at low temperature via a privileged structure and redox chemistry. GREEN CHEMISTRY, [PMID:] [10.1039/D3GC04428A] |
| 2. Xingjie Guo, Peng Hong, Lu Yao, Xudong Liu, Zhicheng Jiang, Bi Shi. (2023) Catalytic hydrogenation of lignin-derived aldehydes over bimetallic PdNi/hydrotalcite catalyst under mild conditions. FUEL, 353 (129231). [PMID:] [10.1016/j.fuel.2023.129231] |
| 3. Zhenyu Li, Enhui Du, Panpan Hao, Liyuan Huai, Yang Zhong, Soliman I. El-Hout, Chunlin Chen, Jian Zhang. (2023) Diluted oxygen realizes high productivity of 2,5-Furandicarboxylic acid under ambient temperature. CATALYSIS TODAY, 423 (114277). [PMID:] [10.1016/j.cattod.2023.114277] |
| 4. Hongjie Zhang, Weijian Chen, Jing Wang, Wenxiang Du, Bibo Wang, Lei Song, Yuan Hu, Xiaopeng Ma. (2023) A novel ROS-activable self-immolative prodrug for tumor-specific amplification of oxidative stress and enhancing chemotherapy of mitoxantrone. BIOMATERIALS, 293 (121954). [PMID:36538847] [10.1016/j.biomaterials.2022.121954] |
| 5. Peng Xie, Wang Zhang, Wugao Wu, Zhuanglin Shen, Mingliang Wang, Yuxiao Lai, Yantao Chen, Zhongfan Jia. (2022) Phenoxyl mediators improve enzymatic degradation of organic pollutants: Effect and mechanism. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 215 (606). [PMID:35750102] [10.1016/j.ijbiomac.2022.06.124] |
| 6. Yue Wei, Si Wu, Zhenqi Liu, Jingsheng Niu, Ya Zhou, Jinsong Ren, Xiaogang Qu. (2022) Tumor associated macrophages reprogrammed by targeted bifunctional bioorthogonal nanozymes for enhanced tumor immunotherapy. Materials Today, 56 (16). [PMID:] [10.1016/j.mattod.2022.01.024] |
| 7. Li Luo, Guangchao Zang, Boyan Liu, Xian Qin, Yuchan Zhang, Yidan Chen, Haijun Zhang, Wei Wu, Guixue Wang. (2021) Bioengineering CXCR4-overexpressing cell membrane functionalized ROS-responsive nanotherapeutics for targeting cerebral ischemia-reperfusion injury. Theranostics, 11 (16): ( 8043–8056). [PMID:34335979] [10.7150/thno.60785] |
| 8. Shouhua Su, Juan Wang, Chao Li, Jinfeng Yuan, Zhicheng Pan, Mingwang Pan. (2021) Short-Branched Fluorinated Polyurethane Coating Exhibiting Good Comprehensive Performance and Potential UV Degradation in Leather Waterproofing Modification. Coatings, 11 (4): (395). [PMID:] [10.3390/coatings11040395] |
| 9. Peng Zeng, Wei-De Zhang. (2021) Photocatalytic hydrogen evolution over a nickel complex anchoring to thiophene embedded g-C3N4. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 596 (75). [PMID:33838327] [10.1016/j.jcis.2021.03.080] |
| 10. Yin Hua, Hu Tiandong, Zhuang Yibin, Liu Tao. (2020) Metabolic engineering of Saccharomyces cerevisiae for high-level production of gastrodin from glucose. Microbial Cell Factories, 19 (1): (1-12). [PMID:33243241] [10.1186/s12934-020-01476-0] |
| 11. Limin Li, Bin Hao, Yulong Zhang, Shen Ji, Guixin Chou. (2020) Metabolite Profiling and Distribution of Militarine in Rats Using UPLC-Q-TOF-MS/MS. MOLECULES, 25 (5): (1082). [PMID:32121087] [10.3390/molecules25051082] |
| 12. Yun-Xiao Zhang, Peng Zeng, Yu-Xiang Yu, Wei-De Zhang. (2020) Integration of nickel complex as a cocatalyst onto in-plane benzene ring-incorporated graphitic carbon nitride nanosheets for efficient photocatalytic hydrogen evolution. CHEMICAL ENGINEERING JOURNAL, 381 (122635). [PMID:] [10.1016/j.cej.2019.122635] |
| 13. Dong Shihao, Wen Ping, Zhang Qi, Li Xinyu, Tan Ken, Nieh James. (2017) Resisting majesty: Apis cerana, has lower antennal sensitivity and decreased attraction to queen mandibular pheromone than Apis mellifera. Scientific Reports, 7 (1): (1-10). [PMID:28294146] [10.1038/srep44640] |
| 14. Yanfen Bai, Hua Yin, Huiping Bi, Yibin Zhuang, Tao Liu, Yanhe Ma. (2016) De novo biosynthesis of Gastrodin in Escherichia coli. METABOLIC ENGINEERING, 35 (138). [PMID:26804288] [10.1016/j.ymben.2016.01.002] |
| 15. Jingying Pan, Jie Fu, Shuguang Deng, Xiuyang Lu. (2015) Distribution coefficient of products from lignin oxidative degradation in organic-water systems. FUEL PROCESSING TECHNOLOGY, 140 (262). [PMID:] [10.1016/j.fuproc.2015.09.016] |
| 16. Jingying Pan, Jie Fu, Xiuyang Lu. (2015) Microwave-Assisted Oxidative Degradation of Lignin Model Compounds with Metal Salts. ENERGY & FUELS, 29 (7): (4503–4509). [PMID:] [10.1021/acs.energyfuels.5b00735] |
References
| 1. Zixin Xie, Xihong Zu, Jinxin Lin, Xueqing Qiu, Tengda Liang, Liheng Chen. (2023) A high-performance lignin flow fuel cell based on self-generating electricity of lignin at low temperature via a privileged structure and redox chemistry. GREEN CHEMISTRY, [PMID:] [10.1039/D3GC04428A] |
| 2. Xingjie Guo, Peng Hong, Lu Yao, Xudong Liu, Zhicheng Jiang, Bi Shi. (2023) Catalytic hydrogenation of lignin-derived aldehydes over bimetallic PdNi/hydrotalcite catalyst under mild conditions. FUEL, 353 (129231). [PMID:] [10.1016/j.fuel.2023.129231] |
| 3. Zhenyu Li, Enhui Du, Panpan Hao, Liyuan Huai, Yang Zhong, Soliman I. El-Hout, Chunlin Chen, Jian Zhang. (2023) Diluted oxygen realizes high productivity of 2,5-Furandicarboxylic acid under ambient temperature. CATALYSIS TODAY, 423 (114277). [PMID:] [10.1016/j.cattod.2023.114277] |
| 4. Hongjie Zhang, Weijian Chen, Jing Wang, Wenxiang Du, Bibo Wang, Lei Song, Yuan Hu, Xiaopeng Ma. (2023) A novel ROS-activable self-immolative prodrug for tumor-specific amplification of oxidative stress and enhancing chemotherapy of mitoxantrone. BIOMATERIALS, 293 (121954). [PMID:36538847] [10.1016/j.biomaterials.2022.121954] |
| 5. Peng Xie, Wang Zhang, Wugao Wu, Zhuanglin Shen, Mingliang Wang, Yuxiao Lai, Yantao Chen, Zhongfan Jia. (2022) Phenoxyl mediators improve enzymatic degradation of organic pollutants: Effect and mechanism. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 215 (606). [PMID:35750102] [10.1016/j.ijbiomac.2022.06.124] |
| 6. Yue Wei, Si Wu, Zhenqi Liu, Jingsheng Niu, Ya Zhou, Jinsong Ren, Xiaogang Qu. (2022) Tumor associated macrophages reprogrammed by targeted bifunctional bioorthogonal nanozymes for enhanced tumor immunotherapy. Materials Today, 56 (16). [PMID:] [10.1016/j.mattod.2022.01.024] |
| 7. Li Luo, Guangchao Zang, Boyan Liu, Xian Qin, Yuchan Zhang, Yidan Chen, Haijun Zhang, Wei Wu, Guixue Wang. (2021) Bioengineering CXCR4-overexpressing cell membrane functionalized ROS-responsive nanotherapeutics for targeting cerebral ischemia-reperfusion injury. Theranostics, 11 (16): ( 8043–8056). [PMID:34335979] [10.7150/thno.60785] |
| 8. Shouhua Su, Juan Wang, Chao Li, Jinfeng Yuan, Zhicheng Pan, Mingwang Pan. (2021) Short-Branched Fluorinated Polyurethane Coating Exhibiting Good Comprehensive Performance and Potential UV Degradation in Leather Waterproofing Modification. Coatings, 11 (4): (395). [PMID:] [10.3390/coatings11040395] |
| 9. Peng Zeng, Wei-De Zhang. (2021) Photocatalytic hydrogen evolution over a nickel complex anchoring to thiophene embedded g-C3N4. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 596 (75). [PMID:33838327] [10.1016/j.jcis.2021.03.080] |
| 10. Yin Hua, Hu Tiandong, Zhuang Yibin, Liu Tao. (2020) Metabolic engineering of Saccharomyces cerevisiae for high-level production of gastrodin from glucose. Microbial Cell Factories, 19 (1): (1-12). [PMID:33243241] [10.1186/s12934-020-01476-0] |
| 11. Limin Li, Bin Hao, Yulong Zhang, Shen Ji, Guixin Chou. (2020) Metabolite Profiling and Distribution of Militarine in Rats Using UPLC-Q-TOF-MS/MS. MOLECULES, 25 (5): (1082). [PMID:32121087] [10.3390/molecules25051082] |
| 12. Yun-Xiao Zhang, Peng Zeng, Yu-Xiang Yu, Wei-De Zhang. (2020) Integration of nickel complex as a cocatalyst onto in-plane benzene ring-incorporated graphitic carbon nitride nanosheets for efficient photocatalytic hydrogen evolution. CHEMICAL ENGINEERING JOURNAL, 381 (122635). [PMID:] [10.1016/j.cej.2019.122635] |
| 13. Dong Shihao, Wen Ping, Zhang Qi, Li Xinyu, Tan Ken, Nieh James. (2017) Resisting majesty: Apis cerana, has lower antennal sensitivity and decreased attraction to queen mandibular pheromone than Apis mellifera. Scientific Reports, 7 (1): (1-10). [PMID:28294146] [10.1038/srep44640] |
| 14. Yanfen Bai, Hua Yin, Huiping Bi, Yibin Zhuang, Tao Liu, Yanhe Ma. (2016) De novo biosynthesis of Gastrodin in Escherichia coli. METABOLIC ENGINEERING, 35 (138). [PMID:26804288] [10.1016/j.ymben.2016.01.002] |
| 15. Jingying Pan, Jie Fu, Shuguang Deng, Xiuyang Lu. (2015) Distribution coefficient of products from lignin oxidative degradation in organic-water systems. FUEL PROCESSING TECHNOLOGY, 140 (262). [PMID:] [10.1016/j.fuproc.2015.09.016] |
| 16. Jingying Pan, Jie Fu, Xiuyang Lu. (2015) Microwave-Assisted Oxidative Degradation of Lignin Model Compounds with Metal Salts. ENERGY & FUELS, 29 (7): (4503–4509). [PMID:] [10.1021/acs.energyfuels.5b00735] |