4-Hydroxycoumarin - 98%, high purity , CAS No.1076-38-6

  • ≥98%
Item Number
H107607
Grouped product items
SKUSizeAvailabilityPrice Qty
H107607-5g
5g
In stock
$9.90
H107607-10g
10g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$13.90
H107607-25g
25g
In stock
$25.90
H107607-100g
100g
In stock
$92.90
H107607-250g
250g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$188.90
H107607-500g
500g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$338.90

Basic Description

Synonyms4-Hydroxy coumarin | 4-Monohydroxycoumarin | AM84328 | Tox21_113421 | 4-Hydroxycoumarin, Vetec(TM) reagent grade, 98% | NSC11889 | NSC-11889 | SCHEMBL131312 | WARFARIN SODIUM IMPURITY B [EP IMPURITY] | 2-Hydroxy-4H-1-benzopyran-4-one | 4-HYDROXY-1-BENZOPY
Specifications & Purity≥98%
Shipped InNormal

Associated Targets(Human)

CA9 Tclin Carbonic anhydrase 9 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CA2 Tclin Carbonic anhydrase II (17698 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALDH2 Tclin Aldehyde dehydrogenase (509 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
XDH Tclin Xanthine dehydrogenase (1038 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AKR1B1 Tclin Aldose reductase (1404 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CSNK2A1 Tchem Casein kinase II alpha (3512 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA1 Tclin Carbonic anhydrase I (13240 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SORD Tchem Sorbitol dehydrogenase (133 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA12 Tclin Carbonic anhydrase XII (6231 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UGT1A4 Tbio UDP-glucuronosyltransferase 1A4 (288 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA9 Tclin Carbonic anhydrase IX (8255 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
A498 (42825 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ACHN (49357 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CAKI-1 (44928 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CCRF-CEM (65223 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
COLO 205 (50209 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DU-145 (51482 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HL-60 (67320 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HT-29 (80576 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
K562 (73714 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KM12 (47707 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
M14 (47487 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MCF7 (126967 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MOLT-4 (49676 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OVCAR-3 (48710 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OVCAR-4 (44535 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OVCAR-5 (45555 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OVCAR-8 (47708 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PC-3 (62116 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RPMI-8226 (44974 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RXF 393 (41971 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SF-295 (48000 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SK-MEL-28 (48833 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SK-MEL3 (228 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SK-MEL-5 (47095 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SN12C (47755 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SNB-19 (46794 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TK-10 (45540 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
U-251 (51189 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
U-937 (7138 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UACC-257 (46019 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UACC-62 (47335 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UO-31 (46270 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
786-0 (47912 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
A549 (127892 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NCI/ADR-RES (33767 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
T47D (39041 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EKVX (44102 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NCI-H322M (45589 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HCC 2998 (41480 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HCT-116 (91556 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

pol Human immunodeficiency virus type 1 integrase (9041 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Aspergillus flavus (8875 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Aspergillus fumigatus (16427 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Dermatophagoides pteronyssinus (58 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trypanosoma cruzi (99888 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Botrytis cinerea (4183 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
B16-F10 (4610 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Colletotrichum gloeosporioides (560 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mbp Myelin basic protein (42 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Maob Monoamine oxidase (439 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Colletotrichum acutatum (300 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Diaporthe ampelina (88 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Phomopsis obscurans (86 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Pubchem Sid488201698
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488201698
IUPAC Name 4-hydroxychromen-2-one
INCHI InChI=1S/C9H6O3/c10-7-5-9(11)12-8-4-2-1-3-6(7)8/h1-5,10H
InChi Key VXIXUWQIVKSKSA-UHFFFAOYSA-N
Canonical SMILES C1=CC=C2C(=C1)C(=CC(=O)O2)O
Isomeric SMILES C1=CC=C2C(=C1)C(=CC(=O)O2)O
WGK Germany 3
RTECS DJ3100000
Alternate CAS 22105-09-5,1076-38-6
PubChem CID 54682930
NSC Number 11889
MeSH Entry Terms 4-hydroxycoumarin;4-OH coumarin
Molecular Weight 162.14
Beilstein 17488
Reaxy-Rn 129768

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

4 results found

Lot NumberCertificate TypeDateItem
F2411186Certificate of AnalysisApr 25, 2024 H107607
B2314047Certificate of AnalysisDec 18, 2021 H107607
D2314044Certificate of AnalysisDec 18, 2021 H107607
H2402022Certificate of AnalysisDec 18, 2021 H107607

Chemical and Physical Properties

Melt Point(°C)213℃

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H302:Harmful if swallowed

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P270:Do not eat, drink or smoke when using this product.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P330:Rinse mouth.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P301+P317:IF SWALLOWED: Get medical help.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 3
RTECS DJ3100000
Reaxy-Rn 129768

Related Documents

Citations of This Product

1. Kuang Yi, Xia Yunlong, Wang Xing, Rao Qingqing, Yang Shengxiang.  (2022)  Magnetic Surface Molecularly Imprinted Polymer for Selective Adsorption of 4-Hydroxycoumarin.  Frontiers in Chemistry,  10    [PMID:35464201] [10.3389/fchem.2022.862777]
2. Yunchang Fan, Dongxu Cai, Xin Wang, Lei Yang.  (2018)  Ionic Liquids: Efficient Media for the Lipase-Catalyzed Michael Addition.  MOLECULES,  23  (9): (2154).  [PMID:30150588] [10.3390/molecules23092154]
3. Yusheng Yuan, Liu Yang, Shaopu Liu, Jidong Yang, Hui Zhang, Jingjing Yan, Xiaoli Hu.  (2017)  Enzyme-catalyzed Michael addition for the synthesis of warfarin and its determination via fluorescence quenching of l-tryptophan.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  176  (183).  [PMID:28095360] [10.1016/j.saa.2017.01.014]
4. Bang-Hua Xie, Zhi Guan, Yan-Hong He.  (2012)  Promiscuous enzyme-catalyzed Michael addition: synthesis of warfarin and derivatives.  JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY,  87  (12): (1709-1714).  [PMID:] [10.1002/jctb.3830]

References

1. Gebauer M.  (2007)  Synthesis and structure-activity relationships of novel warfarin derivatives..  Bioorg Med Chem,  15  (6): (2414-20).  [PMID:17275317] [10.1021/op500134e]
2. Anna Maria Ferrari,Miriam Sgobba,Maria Cristina Gamberini,Giulio Rastelli.  (2007-02-24)  Relationship between quantum-chemical descriptors of proton dissociation and experimental acidity constants of various hydroxylated coumarins. Identification of the biologically active species for xanthine oxidase inhibition..  European journal of medicinal chemistry,  42  ((7)): (1028-1031).  [PMID:17316915]
3. S Stanchev,V Hadjimitova,T Traykov,T Boyanov,I Manolov.  (2008-08-30)  Investigation of the antioxidant properties of some new 4-hydroxycoumarin derivatives..  European journal of medicinal chemistry,  44  ((7)): (3077-3082).  [PMID:18725173]
4. Krzysztof Wójtowicz.  (2008-09-19)  Comparison of the effect of 4-hydroxycoumarin and umbelliferone on the phase transition of dipalmitoylphosphatidylcholine (DPPC) bilayers..  Pharmacological reports : PR,  60  ((4)): (555-560).  [PMID:18799825]
5. Davorka Zavrsnik,Samija Muratović,Selma Spirtović,Dzenita Softić,Marica Medić-Sarić.  (2008-09-26)  The synthesis and antimicrobial activity of some 4-hydroxycoumarin derivatives..  Bosnian journal of basic medical sciences,  ((3)): (277-281).  [PMID:18816263]
6. Vassiliki Panteleon,Ioannis K Kostakis,Panagiotis Marakos,Nicole Pouli,Ioanna Andreadou.  (2008-10-07)  Synthesis and free radical scavenging activity of some new spiropyranocoumarins..  Bioorganic & medicinal chemistry letters,  18  ((21)): (5781-5784).  [PMID:18835711]
7. Davood Nematollahi,Javad Azizian,Mohsen Sargordan-Arani,Mahdi Hesari,Saeed Jameh-Bozorghi,Abdolhamid Alizadeh,Lida Fotouhi,Behrooz Mirza.  (2008-11-05)  Electrochemical synthesis of 4-(dihydroxyphenylthio)-2H-chromen-2-one derivatives..  Chemical & pharmaceutical bulletin,  56  ((11)): (1562-1566).  [PMID:18981606]
8. Pei-Yu Kuo,Rong-Ren Chuang,Ding-Yah Yang.  (2009-02-03)  Reactions of 3-benzoyl-7-dimethylamino-4-hydroxycoumarin and their potential applications in solution- and solid-phase synthesis..  Molecular diversity,  13  ((2)): (253-260).  [PMID:19184500]
9. Nohemí Salinas-Jazmín,Marisol de la Fuente,Ruth Jaimez,Mayra Pérez-Tapia,Armando Pérez-Torres,Marco A Velasco-Velázquez.  (2009-08-20)  Antimetastatic, antineoplastic, and toxic effects of 4-hydroxycoumarin in a preclinical mouse melanoma model..  Cancer chemotherapy and pharmacology,  65  ((5)): (931-940).  [PMID:19690859]
10. Benye Liu,Torben Raeth,Till Beuerle,Ludger Beerhues.  (2009-09-17)  A novel 4-hydroxycoumarin biosynthetic pathway..  Plant molecular biology,  72  ((1-2)): (17-25).  [PMID:19757094]
11. Karen A Nolan,Jeremy R Doncaster,Mark S Dunstan,Katherine A Scott,A David Frenkel,David Siegel,David Ross,John Barnes,Colin Levy,David Leys,Roger C Whitehead,Ian J Stratford,Richard A Bryce.  (2009-11-03)  Synthesis and biological evaluation of coumarin-based inhibitors of NAD(P)H: quinone oxidoreductase-1 (NQO1)..  Journal of medicinal chemistry,  52  ((22)): (7142-7156).  [PMID:19877692]
12. Ingela Fritzson,Bo Svensson,Salam Al-Karadaghi,Björn Walse,Ulf Wellmar,Ulf J Nilsson,Dorthe da Graça Thrige,Stig Jönsson.  (2010-02-26)  Inhibition of human DHODH by 4-hydroxycoumarins, fenamic acids, and N-(alkylcarbonyl)anthranilic acids identified by structure-guided fragment selection..  ChemMedChem,  ((4)): (608-617).  [PMID:20183850]
13. Alfonso Maresca,Claudiu T Supuran.  (2010-06-29)  Coumarins incorporating hydroxy- and chloro-moieties selectively inhibit the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII over the cytosolic ones I and II..  Bioorganic & medicinal chemistry letters,  20  ((15)): (4511-4514).  [PMID:20580555]
14. Atsushi Kato,Kaori Kobayashi,Kayo Narukawa,Yuka Minoshima,Isao Adachi,Shuichi Hirono,Robert J Nash.  (2010-09-02)  6,7-Dihydroxy-4-phenylcoumarin as inhibitor of aldose reductase 2..  Bioorganic & medicinal chemistry letters,  20  ((19)): (5630-5633).  [PMID:20805028]
15. Changning Wang,Chunying Wu,Junqing Zhu,Robert H Miller,Yanming Wang.  (2011-03-12)  Design, synthesis, and evaluation of coumarin-based molecular probes for imaging of myelination..  Journal of medicinal chemistry,  54  ((7)): (2331-2340).  [PMID:21391687]
16. Davorka Završnik,Samija Muratović,Damjan Makuc,Janez Plavec,Mario Cetina,Ante Nagl,Erik De Clercq,Jan Balzarini,Mladen Mintas.  (2011-07-21)  Benzylidene-bis-(4-hydroxycoumarin) and benzopyrano-coumarin derivatives: synthesis, ¹H/¹³C-NMR conformational and X-ray crystal structure studies and in vitro antiviral activity evaluations..  Molecules (Basel, Switzerland),  16  ((7)): (6023-6040).  [PMID:21772234]
17. Sergio A Rodríguez,Mónica A Nazareno,Maria T Baumgartner.  (2011-10-04)  Effect of different C3-aryl substituents on the antioxidant activity of 4-hydroxycoumarin derivatives..  Bioorganic & medicinal chemistry,  19  ((21)): (6233-6238).  [PMID:21964183]
18. Jae-Chul Jung,Eunyoung Lim,Yongnam Lee,Dongguk Min,Jeremy Ricci,Oe-Sook Park,Mankil Jung.  (2012-02-23)  Total synthesis of flocoumafen via knoevenagel condensation and intramolecular ring cyclization: general access to natural products..  Molecules (Basel, Switzerland),  17  ((2)): (2091-2102).  [PMID:22354187]
19. Manoj R Zanwar,Mustafa J Raihan,Sachin D Gawande,Veerababurao Kavala,Donala Janreddy,Chun-Wei Kuo,Ram Ambre,Ching-Fa Yao.  (2012-07-20)  Alcohol mediated synthesis of 4-oxo-2-aryl-4H-chromene-3-carboxylate derivatives from 4-hydroxycoumarins..  The Journal of organic chemistry,  77  ((15)): (6495-6504).  [PMID:22809001]
20. Jia Zhang,Yunfeng Chai,Kezhi Jiang,Huameng Yang,Yuanjiang Pan,Cuirong Sun.  (2012-08-18)  Gas phase retro-Michael reaction resulting from dissociative protonation: fragmentation of protonated warfarin in mass spectrometry..  Journal of mass spectrometry : JMS,  47  ((8)): (1059-1064).  [PMID:22899515]
21. Pen-Yuan Lin,Kuang-Sheng Yeh,Chien-Ling Su,Shiow-Yunn Sheu,Tiffany Chen,Keng-Liang Ou,Mei-Hsiang Lin,Lin-Wen Lee.  (2012-09-12)  Synthesis and antibacterial activities of novel 4-hydroxy-7-hydroxy- and 3-carboxycoumarin derivatives..  Molecules (Basel, Switzerland),  17  ((9)): (10846-10863).  [PMID:22964501]
22. Susan Chen,Ji Zhang,Debra Liao,Mark G Qian.  (2013-08-01)  A novel dynamic flush method to reduce column-related carryover..  Journal of chromatographic science,  52  ((8)): (950-953).  [PMID:23899466]
23. Katrin J Czogalla,Arijit Biswas,Ann-Christin Wendeln,Philipp Westhofen,Clemens R Müller,Matthias Watzka,Johannes Oldenburg.  (2013-08-29)  Human VKORC1 mutations cause variable degrees of 4-hydroxycoumarin resistance and affect putative warfarin binding interfaces..  Blood,  122  ((15)): (2743-2750).  [PMID:23982176]
24. Leticia Mayor-López,Elena Tristante,Mar Carballo-Santana,Estefanía Carrasco-García,Silvina Grasso,Pilar García-Morales,Miguel Saceda,Juan Luján,José García-Solano,Fernando Carballo,Carlos de Torre,Isabel Martínez-Lacaci.  (2014-11-13)  Comparative Study of 17-AAG and NVP-AUY922 in Pancreatic and Colorectal Cancer Cells: Are There Common Determinants of Sensitivity?.  Translational oncology,  ((5)): (590-604).  [PMID:25389454]
25. Zhou-peng Li,Jing Li,Di Qu,Zheng Hou,Xiao-hui Yang,Zi-dan Zhang,Yu-kun Wang,Xiao-xing Luo,Ming-kai Li.  (2015-01-06)  Synthesis and pharmacological evaluations of 4-hydroxycoumarin derivatives as a new class of anti-Staphylococcus aureus agents..  The Journal of pharmacy and pharmacology,  67  ((4)): (573-582).  [PMID:25556550]
26. Lulzime Ballazhi,Emil Popovski,Ahmed Jashari,Faik Imeri,Ibrahim Ibrahimi,Bozhana Mikhova,Kristina Mladenovska.  (2015-03-18)  Potential antiproliferative effect of isoxazolo- and thiazolo coumarin derivatives on breast cancer mediated bone and lung metastases..  Acta pharmaceutica (Zagreb, Croatia),  65  ((1)): (53-63).  [PMID:25781704]
27. Mikael I Naumov,Sergey A Sutirin,Andrey S Shavyrin,Olga G Ganina,Irina P Beletskaya,Véronique Bourgarel-Rey,Sébastien Combes,Jean-Pierre Finet,Alexey Yu Fedorov.  (2007-03-29)  Cascade synthesis of polyoxygenated 6H,11H-[2]benzopyrano-[4,3-c][1]benzopyran-11-ones..  The Journal of organic chemistry,  72  ((9)): (3293-3301).  [PMID:17388631]
28. Stancho Stanchev,Georgi Momekov,Frank Jensen,Ilia Manolov.  (2007-07-07)  Synthesis, computational study and cytotoxic activity of new 4-hydroxycoumarin derivatives..  European journal of medicinal chemistry,  43  ((4)): (694-706).  [PMID:17614164]
29. Ana Carolina Luchini,Patrícia Rodrigues-Orsi,Silvia Helena Cestari,Leonardo Noboru Seito,Aline Witaicenis,Claudia Helena Pellizzon,Luiz Cláudio Di Stasi.  (2008-07-02)  Intestinal anti-inflammatory activity of coumarin and 4-hydroxycoumarin in the trinitrobenzenesulphonic acid model of rat colitis..  Biological & pharmaceutical bulletin,  31  ((7)): (1343-1350).  [PMID:18591772]
30. Dharmesh H Mahajan,Christophe Pannecouque,Erik De Clercq,Kishor H Chikhalia.  (2009-05-06)  Synthesis and studies of new 2-(coumarin-4-yloxy)-4,6-(substituted)-S-triazine derivatives as potential anti-HIV agents..  Archiv der Pharmazie,  342  ((5)): (281-290).  [PMID:19415671]
31. Omaima M Abdelhafez,Kamelia M Amin,Rasha Z Batran,Timothy J Maher,Somaia A Nada,Shalini Sethumadhavan.  (2010-05-04)  Synthesis, anticoagulant and PIVKA-II induced by new 4-hydroxycoumarin derivatives..  Bioorganic & medicinal chemistry,  18  ((10)): (3371-3378).  [PMID:20435480]
32. Ian A Nicholls,Björn C G Karlsson,Annika M Rosengren,Henning Henschel.  (2010-10-30)  Warfarin: an environment-dependent switchable molecular probe..  Journal of molecular recognition : JMR,  23  ((6)): (604-608).  [PMID:21031478]
33. Shizuka Saito,Takatoshi Sakai,Satoru Nemoto,Rieko Matsuda.  (2011-08-30)  [Determination of 4-hydroxycoumarin rodenticides in animal products, fishery products, and honey by liquid chromatography-tandem mass spectrometry]..  Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan,  52  ((4)): (244-250).  [PMID:21873815]
34. Yan Sun,Jing Sun,Chao-Guo Yan.  (2011-12-01)  Synthesis of polyfunctionalized acrylates via one-pot reactions of arylamines, methyl propiolate, aromatic aldehydes, and active methylene compounds..  Molecular diversity,  16  ((1)): (163-171).  [PMID:22127639]
35. Kuang Yi, Xia Yunlong, Wang Xing, Rao Qingqing, Yang Shengxiang.  (2022)  Magnetic Surface Molecularly Imprinted Polymer for Selective Adsorption of 4-Hydroxycoumarin.  Frontiers in Chemistry,  10    [PMID:35464201] [10.3389/fchem.2022.862777]
36. Yunchang Fan, Dongxu Cai, Xin Wang, Lei Yang.  (2018)  Ionic Liquids: Efficient Media for the Lipase-Catalyzed Michael Addition.  MOLECULES,  23  (9): (2154).  [PMID:30150588] [10.3390/molecules23092154]
37. Yusheng Yuan, Liu Yang, Shaopu Liu, Jidong Yang, Hui Zhang, Jingjing Yan, Xiaoli Hu.  (2017)  Enzyme-catalyzed Michael addition for the synthesis of warfarin and its determination via fluorescence quenching of l-tryptophan.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  176  (183).  [PMID:28095360] [10.1016/j.saa.2017.01.014]
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Solution Calculators