4′-Hydroxypropiophenone - 98%, high purity , CAS No.70-70-2

  • ≥98%
Item Number
H107590
Grouped product items
SKUSizeAvailabilityPrice Qty
H107590-25g
25g
In stock
$24.90
H107590-100g
100g
In stock
$43.90
H107590-250g
250g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$79.90
H107590-500g
500g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$144.90
View related series
ketone Non heterocyclic block

Basic Description

Synonyms4'-Hydroxypropiophenone | Paroxypropione | 70-70-2 | 4-Hydroxypropiophenone | 1-(4-hydroxyphenyl)propan-1-one | p-Hydroxypropiophenone | Mepal | Paroxypropion | Frenantol | Frenohypon | Profenone | Proxiphenon | Paroxon | p-Propiophenol | p-Propionylphenol | 1-Propanone, 1-(4-hydroxyp
Specifications & Purity≥98%
Storage TempProtected from light,Argon charged
Shipped InNormal

Associated Targets(Human)

HSD17B3 Tchem Testosterone 17-beta-dehydrogenase 3 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ESR2 Tclin Estrogen receptor beta (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CBX1 Tbio Chromobox protein homolog 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GMNN Tbio Geminin (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
RAPGEF3 Tchem Rap guanine nucleotide exchange factor 3 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ALDH5A1 Tclin Succinate-semialdehyde dehydrogenase, mitochondrial (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HDAC6 Tclin Histone deacetylase 6 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PMP22 Tbio Peripheral myelin protein 22 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ABAT Tclin 4-aminobutyrate aminotransferase, mitochondrial (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
IDH1 Tclin Isocitrate dehydrogenase [NADP] cytoplasmic (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ABAT Tclin Gamma-amino-N-butyrate transaminase (140 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALDH5A1 Tclin Succinate semialdehyde dehydrogenase (19 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HSD17B3 Tchem Estradiol 17-beta-dehydrogenase 3 (821 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GMNN Tbio Geminin (128009 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PMP22 Tbio Peripheral myelin protein 22 (699 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CBX1 Tbio Chromobox protein homolog 1 (92434 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
IDH1 Tclin Isocitrate dehydrogenase [NADP] cytoplasmic (40980 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RAPGEF3 Tchem Rap guanine nucleotide exchange factor 3 (15528 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
LNCaP C4-2B (271 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Colon (26 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TGR Thioredoxin glutathione reductase (28579 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NS1 Nonstructural protein 1 (33327 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ESR1 Estrogen receptor (4 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

Pubchem Sid488180036
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488180036
IUPAC Name 1-(4-hydroxyphenyl)propan-1-one
INCHI InChI=1S/C9H10O2/c1-2-9(11)7-3-5-8(10)6-4-7/h3-6,10H,2H2,1H3
InChi Key RARSHUDCJQSEFJ-UHFFFAOYSA-N
Canonical SMILES CCC(=O)C1=CC=C(C=C1)O
Isomeric SMILES CCC(=O)C1=CC=C(C=C1)O
WGK Germany 3
RTECS UH1925000
PubChem CID 6271
Molecular Weight 150.17
Beilstein 907511
Reaxy-Rn 907511

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

8 results found

Lot NumberCertificate TypeDateItem
D2417312Certificate of AnalysisMar 21, 2024 H107590
D2417336Certificate of AnalysisMar 21, 2024 H107590
D2417339Certificate of AnalysisMar 21, 2024 H107590
C1601147Certificate of AnalysisOct 08, 2023 H107590
G1931152Certificate of AnalysisMay 06, 2023 H107590
B2316335Certificate of AnalysisAug 07, 2021 H107590
G2319519Certificate of AnalysisAug 07, 2021 H107590
H2229639Certificate of AnalysisAug 07, 2021 H107590

Chemical and Physical Properties

SensitivityLight sensitive;Air sensitive
Flash Point(°F)356°F
Flash Point(°C)180°C
Melt Point(°C)150°C

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 3
RTECS UH1925000
Reaxy-Rn 907511
Merck Index 7044

Related Documents

References

1. R Cizmáriková,J Kozlovský.  (1994-10-01)  [Anti-calcium effects of 4-hydroxypropiophenone derivatives--potential beta-adrenoreceptor blockers]..  Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti,  43  ((5)): (226-228).  [PMID:7982006]
2. N J Unakar.  (1970-04-01)  p-Hydroxypropiophenone effects on azo dye-induced alterations in mouse hepatic cells: light and electron microscopic study..  Journal of the National Cancer Institute,  44  ((4)): (873-891).  [PMID:11515055]
3. Rupinder K Lota,Sachin Dhanani,Caroline P Owen,Sabbir Ahmed.  (2006-06-27)  Synthesis, biochemical evaluation and rationalisation of the inhibitory activity of a series of 4-hydroxyphenyl ketones as potential inhibitors of 17beta-hydroxysteroid dehydrogenase type 3 (17beta-HSD3)..  Bioorganic & medicinal chemistry letters,  16  ((17)): (4519-4522).  [PMID:16797984]
4. Alfonso Pérez-Garrido,Aliuska Morales Helguera,Adela Abellán Guillén,M Natália D S Cordeiro,Amalio Garrido Escudero.  (2008-12-06)  Convenient QSAR model for predicting the complexation of structurally diverse compounds with beta-cyclodextrins..  Bioorganic & medicinal chemistry,  17  ((2)): (896-904).  [PMID:19056282]
5. Naomi L Kruhlak,Sydney S Choi,Joseph F Contrera,James L Weaver,James M Willard,Kenneth L Hastings,Lawrence F Sancilio.  (2008-01-01)  Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models..  Toxicology mechanisms and methods,  18  ((2-3)): (217-227).  [PMID:20020916]
6. Zack E Bryant,Romy F J Janser,Medina Jabarkhail,Melissa S Candelaria-Lyons,Brittni B Romero,Severine Van slambrouck,Wim F A Steelant,Ingo Janser.  (2011-01-14)  Inhibitory effects of ethacrynic acid analogues lacking the α,β-unsaturated carbonyl unit and para-acylated phenols on human cancer cells..  Bioorganic & medicinal chemistry letters,  21  ((3)): (912-915).  [PMID:21227691]
7. Morio Yoshimura,Keisuke Ochi,Hiroshi Sekiya,Eiji Tamai,Jun Maki,Atsuko Tada,Naoki Sugimoto,Hiroshi Akiyama,Yoshiaki Amakura.  (2017-09-05)  Identification of Characteristic Phenolic Constituents in Mousouchiku Extract Used as Food Additives..  Chemical & pharmaceutical bulletin,  65  ((9)): (878-882).  [PMID:28867716]
8. Anthony R Horner,Rachael E Wilson,Stephen R Groskreutz,Bridget E Murray,Stephen G Weber.  (2019-01-11)  Evaluation of three temperature- and mobile phase-dependent retention models for reversed-phase liquid chromatographic retention and apparent retention enthalpy..  Journal of chromatography. A,  1589  (73-82).  [PMID:30626503]
9. F da S Knudsen,G Cilento.  (1992-02-01)  Chemiexcitation in the peroxidative metabolism of diethylstilbestrol. Metabolic products..  Photochemistry and photobiology,  55  ((2)): (267-277).  [PMID:1542708]
10. R Cizmáriková,A Dingová,J Kozlovský,O Greksáková.  (1990-11-01)  [Derivatives of para-hydroxyacetophenone and para-hydroxypropiophenone as a potential new beta-adrenolytic agent]..  Ceskoslovenska farmacie,  39  ((9)): (403-408).  [PMID:1982858]
11. R Cizmáriková,E Racanská,O Greksáková.  (1993-04-01)  [Changes in basic nitrogen in a group of potential new beta- adrenolytics--derivatives of p-hydroxyacetophenone and p-hydroxypropiofenone]..  Ceskoslovenska farmacie,  42  ((2)): (82-85).  [PMID:8104716]
12. A Tanner,D J Hopper.  (2000-11-14)  Conversion of 4-hydroxyacetophenone into 4-phenyl acetate by a flavin adenine dinucleotide-containing Baeyer-Villiger-type monooxygenase..  Journal of bacteriology,  182  ((23)): (6565-6569).  [PMID:11073896]

Solution Calculators