4-iodo-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-Benzeneacetamide , CAS No.942296-25-5

Item Number

I487379

Grouped product items
SKU	Size	Availability	Price	Qty
I487379-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$315.90

Basic Description

Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	Description PHL is a strong inhibitor of several LuxR-type receptors, including LuxR fromV. fischeri,TraR fromA. tumefaciens, the putative LuxR-type receptor fromA. baumannii– AbaR, and RhlR fromP.aeruginosa. This compound represents a good choice for initial testing of LuxR-type receptor inhibition.

Associated Targets(non-human)

luxR Transcriptional activator protein luxR (400 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

traR Transcriptional activator protein traR (147 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

lasR Transcriptional activator protein lasR (432 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	2-(4-iodophenyl)-N-[(3S)-2-oxooxolan-3-yl]acetamide
INCHI	InChI=1S/C12H12INO3/c13-9-3-1-8(2-4-9)7-11(15)14-10-5-6-17-12(10)16/h1-4,10H,5-7H2,(H,14,15)/t10-/m0/s1
InChi Key	IMJUHEKUNKCNGB-JTQLQIEISA-N
Canonical SMILES	C1COC(=O)C1NC(=O)CC2=CC=C(C=C2)I
Isomeric SMILES	C1COC(=O)[C@H]1NC(=O)CC2=CC=C(C=C2)I
PubChem CID	25014705
Molecular Weight	345.13

References

1. Michael A Welsh, Nora R Eibergen, Joseph D Moore, Helen E Blackwell,. (2015-01-13) Small molecule disruption of quorum sensing cross-regulation in pseudomonas aeruginosa causes major and unexpected alterations to virulence phenotypes.. Journal of the American Chemical Society, 137 ((4)): ( 1510-1519 ). [PMID:25574853]

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Basic Description