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4-Methyl-2-(1-piperidinyl)-quinoline - 10mM in DMSO, high purity , CAS No.5465-86-1(DMSO)
Basic Description Synonyms 5465-86-1 | ML204 | 4-methyl-2-(piperidin-1-yl)quinoline | ML 204 | 4-methyl-2-piperidin-1-ylquinoline | 4-Methyl-2-(1-piperidinyl)-quinoline | 4-Methyl-2-(1-piperidinyl)quinoline | 5465-86-1 (free base) | ML-204 | VU0024172-3 | NSC25850 | Cambridge id 5563912 | MLS001007138 | 4-m Specifications & Purity Moligand™, 10mM in DMSO Biochemical and Physiological Mechanisms Blocker of TRPC4 channels (IC50values are 0.96 and 2.6μM in fluorescent and electrophysiological assays, respectively). Exhibits 19-fold selectivity against TRPC6 and 9-fold selectivity against TRPC5; displays no significant activity at TRPV1, TRPV3, TRPA Storage Temp Store at -80°C Shipped In Ice chest + Ice pads Grade Moligand™
Associated Targets(Human) Associated Targets(non-human) Names and Identifiers IUPAC Name 4-methyl-2-piperidin-1-ylquinoline INCHI InChI=1S/C15H18N2/c1-12-11-15(17-9-5-2-6-10-17)16-14-8-4-3-7-13(12)14/h3-4,7-8,11H,2,5-6,9-10H2,1H3 InChi Key USYRQXDHKXGTCK-UHFFFAOYSA-N Canonical SMILES CC1=CC(=NC2=CC=CC=C12)N3CCCCC3 Isomeric SMILES CC1=CC(=NC2=CC=CC=C12)N3CCCCC3 WGK Germany 3 PubChem CID 230710 Molecular Weight 226.32
Chemical and Physical Properties Solubility Solvent:DMSO, Max Conc. mg/mL: 22.63, Max Conc. mM: 100; Solvent:1eq. HCl, Max Conc. mg/mL: 5.66, Max Conc. mM: 25 with gentle warming
Safety and Hazards(GHS) Hazard Statements H302: Harmful if swallowed
WGK Germany 3
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