(4-Methyl-2-oxochromen-7-yl) furan-2-carboxylate , CAS No.87468-02-8

Item Number
M668456
Grouped product items
SKUSizeAvailabilityPrice Qty
M668456-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$999.90
M668456-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,999.90

Basic Description

Synonyms(4-methyl-2-oxochromen-7-yl) furan-2-carboxylate | 4-methyl-2-oxo-2H-chromen-7-yl furan-2-carboxylate | MLS000712758 | 2-Furancarboxylic acid, 4-methyl-2-oxo-2H-1-benzopyran-7-yl ester | SMR000282525 | ChemDiv2_000087 | Oprea1_667731 | Oprea1_783928 | CBD

Product Properties

ALogP3.1

Associated Targets(Human)

F2 Tclin Prothrombin (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
F2 Tclin Thrombin (11687 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
F12 Tchem Coagulation factor XII (1450 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SMPD1 Tchem Sphingomyelin phosphodiesterase (13561 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GMNN Tbio Geminin (128009 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KMT2A Tchem Histone-lysine N-methyltransferase MLL (17327 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CBX1 Tbio Chromobox protein homolog 1 (92434 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ATXN2 Tbio Ataxin-2 (54410 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Luciferin 4-monooxygenase (66902 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Impa1 Inositol monophosphatase 1 (16203 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NS1 Nonstructural protein 1 (33327 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
3C-like protease (101 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name (4-methyl-2-oxochromen-7-yl) furan-2-carboxylate
INCHI InChI=1S/C15H10O5/c1-9-7-14(16)20-13-8-10(4-5-11(9)13)19-15(17)12-3-2-6-18-12/h2-8H,1H3
InChi Key WVAYNWNBGPUATF-UHFFFAOYSA-N
Canonical SMILES CC1=CC(=O)OC2=C1C=CC(=C2)OC(=O)C3=CC=CO3
Isomeric SMILES CC1=CC(=O)OC2=C1C=CC(=C2)OC(=O)C3=CC=CO3
PubChem CID 728528
Molecular Weight 270.24

Certificates

Certificate of Analysis(COA)

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Related Documents

Citations of This Product

1. Kechun Chen, Bingtian Xu, Xuan Xiao, Lu Long, Qian Zhao, Zicen Fang, Xingxing Tu, Jiakang Wang, Jiangping Xu, Haitao Wang.  (2024)  Involvement of CKS1B in the anti-inflammatory effects of cannabidiol in experimental stroke models.  EXPERIMENTAL NEUROLOGY,  373  (114654).  [PMID:38104887] [10.1016/j.expneurol.2023.114654]
2. Shi Jiachen, Ma Qiuling, Su Wenting, Liu Congyan, Zhang Huangqin, Liu Yuping, Li Xiaoqi, Jiang Xi, Ge Chang, Kong Fei, Chen Yan, Qu Ding.  (2023)  Effervescent cannabidiol solid dispersion-doped dissolving microneedles for boosted melanoma therapy via the “TRPV1-NFATc1-ATF3” pathway and tumor microenvironment engineering.  Biomaterials Research,  27  (1): (1-15).  [PMID:37198657] [10.1186/s40824-023-00390-x]
3. Qunfang Yang, Tao Liu, Haiping Zheng, Zechen Zhou, Yan Huang, Honglin Jia, Shixiang Fu, Xuan Zhang, Haigang Zhang, Ya Liu, Xiaohong Chen, Wenjun Shan.  (2023)  A nanoformulation for immunosuppression reversal and broad-spectrum self-amplifying antitumor ferroptosis-immunotherapy.  BIOMATERIALS,  292  (121936).  [PMID:36502663] [10.1016/j.biomaterials.2022.121936]
4. Xu Bing-tian, Li Meng-fan, Chen Ke-chun, Li Xing, Cai Ning-bo, Xu Jiang-ping, Wang Hai-tao.  (2022)  Mitofusin-2 mediates cannabidiol-induced neuroprotection against cerebral ischemia in rats.  ACTA PHARMACOLOGICA SINICA,  44  (3): (499-512).  [PMID:36229600] [10.1038/s41401-022-01004-3]
5. Yongzhou Yu, Zuxiao Yang, Baohua Jin, Xia Qin, Xiaoque Zhu, Jiahui Sun, Lifang Huo, Ri Wang, Yongyun Shi, Zhanfeng Jia, Yun Stone Shi, Shifeng Chu, Dezhi Kong, Wei Zhang.  (2020)  Cannabidiol inhibits febrile seizure by modulating AMPA receptor kinetics through its interaction with the N-terminal domain of GluA1/GluA2.  PHARMACOLOGICAL RESEARCH,  161  (105128).  [PMID:32805354] [10.1016/j.phrs.2020.105128]

References

1. Kechun Chen, Bingtian Xu, Xuan Xiao, Lu Long, Qian Zhao, Zicen Fang, Xingxing Tu, Jiakang Wang, Jiangping Xu, Haitao Wang.  (2024)  Involvement of CKS1B in the anti-inflammatory effects of cannabidiol in experimental stroke models.  EXPERIMENTAL NEUROLOGY,  373  (114654).  [PMID:38104887] [10.1016/j.expneurol.2023.114654]
2. Shi Jiachen, Ma Qiuling, Su Wenting, Liu Congyan, Zhang Huangqin, Liu Yuping, Li Xiaoqi, Jiang Xi, Ge Chang, Kong Fei, Chen Yan, Qu Ding.  (2023)  Effervescent cannabidiol solid dispersion-doped dissolving microneedles for boosted melanoma therapy via the “TRPV1-NFATc1-ATF3” pathway and tumor microenvironment engineering.  Biomaterials Research,  27  (1): (1-15).  [PMID:37198657] [10.1186/s40824-023-00390-x]
3. Qunfang Yang, Tao Liu, Haiping Zheng, Zechen Zhou, Yan Huang, Honglin Jia, Shixiang Fu, Xuan Zhang, Haigang Zhang, Ya Liu, Xiaohong Chen, Wenjun Shan.  (2023)  A nanoformulation for immunosuppression reversal and broad-spectrum self-amplifying antitumor ferroptosis-immunotherapy.  BIOMATERIALS,  292  (121936).  [PMID:36502663] [10.1016/j.biomaterials.2022.121936]
4. Xu Bing-tian, Li Meng-fan, Chen Ke-chun, Li Xing, Cai Ning-bo, Xu Jiang-ping, Wang Hai-tao.  (2022)  Mitofusin-2 mediates cannabidiol-induced neuroprotection against cerebral ischemia in rats.  ACTA PHARMACOLOGICA SINICA,  44  (3): (499-512).  [PMID:36229600] [10.1038/s41401-022-01004-3]
5. Yongzhou Yu, Zuxiao Yang, Baohua Jin, Xia Qin, Xiaoque Zhu, Jiahui Sun, Lifang Huo, Ri Wang, Yongyun Shi, Zhanfeng Jia, Yun Stone Shi, Shifeng Chu, Dezhi Kong, Wei Zhang.  (2020)  Cannabidiol inhibits febrile seizure by modulating AMPA receptor kinetics through its interaction with the N-terminal domain of GluA1/GluA2.  PHARMACOLOGICAL RESEARCH,  161  (105128).  [PMID:32805354] [10.1016/j.phrs.2020.105128]

Solution Calculators