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4-(N-nitrosomethylamino)-1-(3-pyridyl)-1-butanone - 98%, high purity , CAS No.64091-91-4
Basic Description Synonyms 64091-91-4 | 4-(N-Nitrosomethylamino)-1-(3-pyridyl)-1-butanone | 4-(METHYLNITROSAMINO)-1-(3-PYRIDYL)-1-BUTANONE | NNK | NNK (carcinogen) | 4-(N-Methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | 1-Butanone, 4-(methylnitrosoamino)-1-(3-pyridinyl)- | CCRIS 1150 | 4-(N-Nitros Specifications & Purity ≥95% Storage Temp Store at 2-8°C,Protected from light,Argon charged Shipped In Wet ice Product Description
Product Describtion:
NNK is a nitrosate derivative of nicotine. NNK activates ERK1/2 and PKC α， Simultaneously stimulating Bcl2 phosphorylation in Ser70 and c-Myc in Thr58 and Ser62. NNK can induce the survival and proliferation of human lung cancer cells. NNK can be used to construct a lung cancer mouse model.
Associated Targets(Human) Names and Identifiers IUPAC Name N-methyl-N-(4-oxo-4-pyridin-3-ylbutyl)nitrous amide INCHI InChI=1S/C10H13N3O2/c1-13(12-15)7-3-5-10(14)9-4-2-6-11-8-9/h2,4,6,8H,3,5,7H2,1H3 InChi Key FLAQQSHRLBFIEZ-UHFFFAOYSA-N Canonical SMILES CN(CCCC(=O)C1=CN=CC=C1)N=O Isomeric SMILES CN(CCCC(=O)C1=CN=CC=C1)N=O PubChem CID 47289 UN Number 2811 Packing Group I Molecular Weight 207.23
Chemical and Physical Properties Sensitivity Light、Moisture sensitive Melt Point(°C) 63-65℃
Safety and Hazards(GHS) Pictogram(s) GHS06 , GHS08 , GHS07 Signal Danger Hazard Statements H301: Toxic if swallowed
Class 6.1
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