Grouped product items

SKU

Size

Availability

Price

Qty

N105745-25g

25g

In stock

$16.90

N105745-100g

100g

In stock

$37.90

N105745-500g

500g

Available within 4-8 weeks(?)

$93.90

Basic Description

Synonyms	4'-Nitroacetophenone \| 100-19-6 \| p-Nitroacetophenone \| 1-(4-Nitrophenyl)ethanone \| 4-NITROACETOPHENONE \| p-Acetylnitrobenzene \| Ethanone, 1-(4-nitrophenyl)- \| p-Nitrophenyl methyl ketone \| 1-(4-Nitrophenyl)ethan-1-one \| Paranitroacetophenone \| Acetophenone, 4'-nitro- \| Methyl
Specifications & Purity	≥97%
Shipped In	Normal

Associated Targets(Human)

GMNN Tbio Geminin (0 Activities)

Discover Target: GMNN

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

AR Tclin Androgen receptor (0 Activities)

Discover Target: AR

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NFE2L2 Tchem Nuclear factor erythroid 2-related factor 2 (0 Activities)

Discover Target: NFE2L2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CXCL8 Tchem Interleukin-8 (0 Activities)

Discover Target: CXCL8

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MAPK1 Tchem Mitogen-activated protein kinase 1 (0 Activities)

Discover Target: MAPK1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

AR Tclin Androgen Receptor (11781 Activities)

Discover Target: AR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CXCL8 Tchem Interleukin-8 (642 Activities)

Discover Target: CXCL8

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GMNN Tbio Geminin (128009 Activities)

Discover Target: GMNN

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Mapk1 MAP kinase ERK2 (650 Activities)

Discover Target: Mapk1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Salmonella typhimurium (15756 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Plasmodium falciparum (966862 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Akr1c9 3-alpha-hydroxysteroid dehydrogenase (27 Activities)

Discover Target: Akr1c9

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)

Discover Target: Nfe2l2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

Pubchem Sid	488180459
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488180459
IUPAC Name	1-(4-nitrophenyl)ethanone
INCHI	InChI=1S/C8H7NO3/c1-6(10)7-2-4-8(5-3-7)9(11)12/h2-5H,1H3
InChi Key	YQYGPGKTNQNXMH-UHFFFAOYSA-N
Canonical SMILES	CC(=O)C1=CC=C(C=C1)[N+](=O)[O-]
Isomeric SMILES	CC(=O)C1=CC=C(C=C1)[N+](=O)[O-]
WGK Germany	3
RTECS	AM9627000
PubChem CID	7487
UN Number	2811
Packing Group	I
Molecular Weight	165.14
Beilstein	7288
Reaxy-Rn	607777

Certificates

Certificate of Analysis(COA)

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To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

6 results found

Lot Number	Certificate Type	Date	Item
I2404102	Certificate of Analysis	Sep 11, 2024	N105745
F2411368	Certificate of Analysis	Apr 25, 2024	N105745
D1629070	Certificate of Analysis	Dec 19, 2023	N105745
D2321427	Certificate of Analysis	May 06, 2022	N105745
D2321429	Certificate of Analysis	May 06, 2022	N105745
G1811028	Certificate of Analysis	May 06, 2022	N105745

Chemical and Physical Properties

Solubility	Easily soluble in hot ethanol, ether, and benzene, insoluble in water.
Boil Point(°C)	202°C
Melt Point(°C)	79°C

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
WGK Germany	3
RTECS	AM9627000
Reaxy-Rn	607777
Class	6.1

Citations of This Product

1. Kai Sun, Yuewen Shao, Cong Ming, Mengjiao Fan, Huailin Fan, Lijun Zhang, Shu Zhang, Yi Wang, Guozhu Chen, Xun Hu. (2023) Copper-based catalysts synthesized during hydrogenation. CHEMICAL ENGINEERING SCIENCE, 276 (118819). [PMID:]

References

1. H B Michaels. (1986-07-01) Oxygen depletion in irradiated aqueous solutions containing electron affinic hypoxic cell radiosensitizers.. International journal of radiation oncology, biology, physics, 12 ((7)): (1055-1058). [PMID:3744926]
2. A M Rauth,R A McClelland,H B Michaels,R Battistella. (1984-08-01) The oxygen dependence of the reduction of nitroimidazoles in a radiolytic model system.. International journal of radiation oncology, biology, physics, 10 ((8)): (1323-1326). [PMID:6236187]
3. M V Lafleur,H Loman. (1982-03-01) Influence of anoxic sensitizers on the radiation damage in biologically active DNA in aqueous solution.. International journal of radiation biology and related studies in physics, chemistry, and medicine, 41 ((3)): (295-302). [PMID:6279534]
4. M Abe,M Takahashi,K Ono,M Hiraoka. (1982-06-01) [Cancer and radiotherapy. (4). Hypoxic cell sensitizers and hyperthermia combined with radiation in cancer treatment].. Iyo denshi to seitai kogaku. Japanese journal of medical electronics and biological engineering, 20 ((3)): (203-209). [PMID:6759728]
5. G J Fisher,B M Sutherland,J C Sutherland. (1983-05-01) Action spectra for ultraviolet photosensitized killing of mammalian cells by misonidazole and para-nitroacetophenone.. Radiation research, 94 ((2)): (231-238). [PMID:6856772]
6. K Tatsumi,A Inoue,H Yoshimura. (1981-02-01) Mode of reactions between xanthine oxidase and aromatic nitro compounds.. Journal of pharmacobio-dynamics, 4 ((2)): (101-108). [PMID:6895090]
7. Y G Smeyers,A De Bueren,R Alcala,M V Alvarez. (1981-06-01) Theoretical approach for radiosensitizers. Correlation between calculated electroaffinity and sensitization factors of nitro-compounds.. International journal of radiation biology and related studies in physics, chemistry, and medicine, 39 ((6)): (649-653). [PMID:6972930]
8. B C Millar,E M Fielden,T C Jenkins. (1981-11-01) The effect of combinations of nitroaromatic and nitroxyl radiosensitizers on the radiation survival response of Chinese hamster cells, V.79-753B, in vitro.. Radiation research, 88 ((2)): (369-376). [PMID:7302142]
9. C M Krishna,A K Roy. (1993-02-01) Study of photodynamic reactions of p-nitroacetophenone using ESR and optical techniques.. Indian journal of biochemistry & biophysics, 30 ((1)): (7-9). [PMID:8389727]
10. N Iwata,N Inazu,S Hara,T Yanase,S Kano,T Endo,F Kuriiwa,Y Sato,T Satoh. (1993-04-22) Interindividual variability of carbonyl reductase levels in human livers.. Biochemical pharmacology, 45 ((8)): (1711-1714). [PMID:8484808]
11. J M Wong,W Kalow,D Kadar,Y Takamatsu,T Inaba. (1993-04-01) Carbonyl (phenone) reductase in human liver: inter-individual variability.. Pharmacogenetics, 3 ((2)): (110-115). [PMID:8518835]
12. E M Fielden,D Ewing,P B Roberts. (1974-06-01) Additive effects in the radiosensitization of B. megaterium spores by p-nitroacetophenone and norpseudopelletierine-N-oxyl.. Radiation research, 58 ((3)): (489-497). [PMID:10876639]
13. Wing-Yin Tsang,John P Richard. (2009-10-01) Structure-reactivity effects on primary deuterium isotope effects on protonation of ring-substituted alpha-methoxystyrenes.. Journal of the American Chemical Society, 131 ((39)): (13952-13962). [PMID:19788330]
14. Amy Christiansen,Alexa Peterson,Scott C Anderson,Riley Lass,Maja Johnson,Amanda M Nienow. (2015-12-01) Analysis of the Photodegradation of the Imidazolinone Herbicides Imazamox, Imazapic, Imazaquin, and Imazamethabenz-methyl in Aqueous Solution.. Journal of agricultural and food chemistry, 63 ((50)): (10768-10777). [PMID:26616105]
15. Reid P Milstead,Keeton T Nance,Kulananalu S Tarnas,Kira E Egelhofer,David R Griffith. (2018-09-14) Photochemical degradation of halogenated estrogens under natural solar irradiance.. Environmental science. Processes & impacts, 20 ((10)): (1350-1360). [PMID:30211921]
16. Priya I Hora,William A Arnold. (2020-05-15) Photochemical fate of quaternary ammonium compounds in river water.. Environmental science. Processes & impacts, 22 ((6)): (1368-1381). [PMID:32406464]
17. P J Rao,E Bothe,D Schulte-Frohlinde. (1992-05-01) Reaction of dithiothreitol and para-nitroacetophenone with different radical precursors of .OH radical-induced strand break formation of single-stranded DNA in anoxic aqueous solution.. International journal of radiation biology, 61 ((5)): (577-591). [PMID:1349622]
18. R F Anderson,K B Patel. (1983-03-01) Metabolic potentiation of the radiosensitization of hypoxic bacterial cells afforded by nitroaromatic compounds.. Radiation research, 93 ((3)): (516-524). [PMID:6344127]
19. K Washino,W Schnabel. (1982-03-01) Radiation-induced molecular size changes in DNA in the presence of p-nitroacetophenone. Pulse radiolysis in conjunction with light-scattering measurements.. International journal of radiation biology and related studies in physics, chemistry, and medicine, 41 ((3)): (271-282). [PMID:6978317]
20. C T Aravindakumar,H Mohan,M Mudaliar,B S Rao,J P Mittal,M N Schuchmann,C Von Sonntag. (1994-10-01) Addition of e-aq and H atoms to hypoxanthine and inosine and the reactions of alpha-hydroxyalkyl radicals with purines. A pulse radiolysis and product analysis study.. International journal of radiation biology, 66 ((4)): (351-365). [PMID:7930837]
21. N Cénas,K Ollinger. (1994-11-15) Redox conversions of methemoglobin during redox cycling of quinones and aromatic nitrocompounds.. Archives of biochemistry and biophysics, 315 ((1)): (170-176). [PMID:7979395]
22. O A Barski,K Watanabe. (1993-04-05) Kinetic mechanism of ketoreductase activity of prostaglandin F synthase from bovine lung.. FEBS letters, 320 ((2)): (107-110). [PMID:8458424]
23. D A Agnew,L D Skarsgard. (1974-02-01) Chemical radiosensitization of anoxic mammalian cells: effect of cell concentration.. Radiation research, 57 ((2)): (246-259). [PMID:10874940]
24. D Ewing,E M Fielden,P B Roberts. (1974-06-01) Modification of radiation sensitivity of Bacillus megaterium spores by N2O and p-nitroacetophenone.. Radiation research, 58 ((3)): (481-488). [PMID:10876638]
25. Grant C Wallace,Michael Sander,Yu-Ping Chin,William A Arnold. (2017-05-04) Quantifying the electron donating capacities of sulfide and dissolved organic matter in sediment pore waters of wetlands.. Environmental science. Processes & impacts, 19 ((5)): (758-767). [PMID:28466914]
26. Lise Schoonen,Kayleigh S van Esterik,Chunqiu Zhang,Rein V Ulijn,Roeland J M Nolte,Jan C M van Hest. (2017-11-09) Alternative application of an affinity purification tag: hexahistidines in ester hydrolysis.. Scientific reports, 7 ((1)): (14772-14772). [PMID:29116178]
27. Katryn L Williams,Richie Kaur,Alexander S McFall,Jacob Kalbfleisch,Joshua J Gladfelder,David B Ball,Cort Anastasio,Ronald S Tjeerdema. (2018-05-15) Aqueous Photolysis of Benzobicyclon Hydrolysate.. Journal of agricultural and food chemistry, 66 ((22)): (5462-5472). [PMID:29754487]
28. Kai Sun, Yuewen Shao, Cong Ming, Mengjiao Fan, Huailin Fan, Lijun Zhang, Shu Zhang, Yi Wang, Guozhu Chen, Xun Hu. (2023) Copper-based catalysts synthesized during hydrogenation. CHEMICAL ENGINEERING SCIENCE, 276 (118819). [PMID:]

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4′-Nitroacetophenone - 97%, high purity , CAS No.100-19-6