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SKU

Size

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Price

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N106144-25g

25g

Available within 4-8 weeks(?)

$16.90

N106144-100g

100g

Available within 4-8 weeks(?)

$22.90

N106144-250g

250g

In stock

$40.90

N106144-500g

500g

In stock

$72.90

Basic Description

Synonyms	4-Nitrobenzoyl chloride \| 122-04-3 \| P-NITROBENZOYL CHLORIDE \| Benzoyl chloride, 4-nitro- \| 4-Nitrobenzoic acid chloride \| p-Nitrobenzoic acid chloride \| 4-Nitro-benzoyl chloride \| Benzoyl chloride, p-nitro- \| para-nitrobenzoyl chloride \| 4-Nitrobenzoyl-d4Chloride \| Nitroben
Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	4-Nitrobenzoyl chloride reacts with triphenylphosphonium salt to synthesize benzofurans (potential positron emission tomography (PET) tracers) by the intramolecular Wittig reaction.It has been used for the derivatisation of Adiol (Androstenediol, an endog
Storage Temp	Room temperature,Desiccated
Shipped In	Normal

Associated Targets(Human)

APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (0 Activities)

Discover Target: APEX1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ALDH1A1 Tchem Retinal dehydrogenase 1 (0 Activities)

Discover Target: ALDH1A1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)

Discover Target: ALDH1A1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Lymphoblastoid cell (5959 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)

Discover Target: APEX1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Rattus norvegicus (775804 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	4-nitrobenzoyl chloride
INCHI	InChI=1S/C7H4ClNO3/c8-7(10)5-1-3-6(4-2-5)9(11)12/h1-4H
InChi Key	SKDHHIUENRGTHK-UHFFFAOYSA-N
Canonical SMILES	C1=CC(=CC=C1C(=O)Cl)[N+](=O)[O-]
Isomeric SMILES	C1=CC(=CC=C1C(=O)Cl)[N+](=O)[O-]
WGK Germany	2
RTECS	DM6651000
PubChem CID	8502
UN Number	1759
Packing Group	I
Molecular Weight	185.56
Beilstein	473192

Certificates

Certificate of Analysis(COA)

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17 results found

Lot Number	Certificate Type	Date	Item
A2206183	Certificate of Analysis	Oct 07, 2023	N106144
A2206184	Certificate of Analysis	Oct 07, 2023	N106144
A2206186	Certificate of Analysis	Oct 07, 2023	N106144
A2206181	Certificate of Analysis	Oct 07, 2023	N106144
I2320322	Certificate of Analysis	Sep 27, 2023	N106144
I2320321	Certificate of Analysis	Sep 27, 2023	N106144
I2320320	Certificate of Analysis	Sep 27, 2023	N106144
I2320310	Certificate of Analysis	Sep 27, 2023	N106144
A2206188	Certificate of Analysis	Sep 11, 2023	N106144
H2209686	Certificate of Analysis	Aug 26, 2022	N106144
D2307433	Certificate of Analysis	Aug 26, 2022	N106144
H2209682	Certificate of Analysis	Aug 24, 2022	N106144
H2209683	Certificate of Analysis	Aug 24, 2022	N106144
H2209684	Certificate of Analysis	Aug 24, 2022	N106144
H2209685	Certificate of Analysis	Aug 24, 2022	N106144
C2229002	Certificate of Analysis	Mar 29, 2022	N106144
E2006022	Certificate of Analysis	Feb 16, 2022	N106144

Chemical and Physical Properties

Solubility	Soluble in Ether,Benzene,Acetone,Toluene
Sensitivity	Hygroscopic.
Flash Point(°F)	215.6 °F - closed cup
Flash Point(°C)	102℃
Boil Point(°C)	202-205°C（14kPa）
Melt Point(°C)	73°C

Safety and Hazards(GHS)

Pictogram(s)	GHS08, GHS05
Signal	Danger
Hazard Statements	H314:Causes severe skin burns and eye damage H290:May be corrosive to metals
Precautionary Statements	P280:Wear protective gloves/protective clothing/eye protection/face protection. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P363:Wash contaminated clothing before reuse. P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. P302+P361+P354:IF ON SKIN: Take off Immediately all contaminated clothing. Immediately rinse with water for several minutes. P316:Get emergency medical help immediately.
WGK Germany	2
RTECS	DM6651000
Class	8
Merck Index	6589

Citations of This Product

1. Jing Ye, Qinghua Li, Yushan Zhang, Qi Su, Zujian Feng, Pingsheng Huang, Chuangnian Zhang, Yinglei Zhai, Weiwei Wang. (2023) ROS scavenging and immunoregulative EGCG@Cerium complex loaded in antibacterial polyethylene glycol-chitosan hydrogel dressing for skin wound healing. Acta Biomaterialia, [PMID:37230435]
2. Ge Zhu, Haoji Lao, Feng Feng, Minyan Wang, Xingzhong Fang, Guofei Chen. (2022) Synthesis and characterization of poly(amide-imide)s with high Tg and low CTE derived from isomeric amide-containing diamines. EUROPEAN POLYMER JOURNAL, 179 (111558). [PMID:]
3. Shengdao Wang, Shuwen Zhang, Yanchao Yang, Zhongxin Dong, Guibin Wang. (2022) Direct electrochemical grafting of crystalline PAEK macromolecule on carbon fiber to enhance the interfacial properties of PEEK/CF composites. COMPOSITES SCIENCE AND TECHNOLOGY, 220 (109262). [PMID:]

References

1. G Lindwall,T D Boyer. (1987-04-15) Excretion of glutathione conjugates by primary cultured rat hepatocytes.. The Journal of biological chemistry, 262 ((11)): (5151-5158). [PMID:3558387]
2. S Nojiri,N Taguchi,M Oishi,S Suzuki. (2000-10-24) Determination of sugar alcohols in confectioneries by high-performance liquid chromatography after nitrobenzoylation.. Journal of chromatography. A, 893 ((1)): (195-200). [PMID:11043600]
3. Tatsuya Higashi,Yasuaki Ninomiya,Naoko Iwaki,Akinori Yamauchi,Naoki Takayama,Kazutake Shimada. (2006-04-20) Studies on neurosteroids XVIII LC-MS analysis of changes in rat brain and serum testosterone levels induced by immobilization stress and ethanol administration.. Steroids, 71 ((7)): (609-617). [PMID:16620893]
4. Tatsuya Higashi,Naoki Takayama,Mariko Kyutoku,Kazutake Shimada,Eitetsu Koh,Mikio Namiki. (2006-09-19) Liquid chromatography-mass spectrometric assay of androstenediol in prostatic tissue: influence of androgen deprivation therapy on its level.. Steroids, 71 ((11-12)): (1007-1013). [PMID:16978674]
5. Mateusz Janeta,Łukasz John,Jolanta Ejfler,Sławomir Szafert. (2014-10-11) High-yield synthesis of amido-functionalized polyoctahedral oligomeric silsesquioxanes by using acyl chlorides.. Chemistry (Weinheim an der Bergstrasse, Germany), 20 ((48)): (15966-15974). [PMID:25302846]
6. J Foussereau. (1989-05-01) Accidental occupational sensitization to p-nitrobenzoyl chloride in a chemistry student synthesizing procaine.. Contact dermatitis, 20 ((5)): (397-398). [PMID:2766713]
7. M Ishigai,J I Langridge,R S Bordoli. (2001-10-25) A new approach for dynamics of enzyme-catalyzed glutathione conjugation by electrospray quadrupole/time-of-flight mass spectrometry.. Analytical biochemistry, 298 ((1)): (83-92). [PMID:11673899]
8. Meng-Ge Huangfu,Deng-Xiong Shen,Xin-Xin Zhi,Yan Zhang,Yan-Jiang Jia,Yuan-Cheng An,Xin-Ying Wei,Jin-Gang Liu. (2021-03-07) Preparation and Characterization of Electrospun Fluoro-Containing Poly(imide-benzoxazole) Nano-Fibrous Membranes with Low Dielectric Constants and High Thermal Stability.. Nanomaterials (Basel, Switzerland), 11 ((2)): [PMID:33669852]
9. Jing Ye, Qinghua Li, Yushan Zhang, Qi Su, Zujian Feng, Pingsheng Huang, Chuangnian Zhang, Yinglei Zhai, Weiwei Wang. (2023) ROS scavenging and immunoregulative EGCG@Cerium complex loaded in antibacterial polyethylene glycol-chitosan hydrogel dressing for skin wound healing. Acta Biomaterialia, [PMID:37230435]
10. Ge Zhu, Haoji Lao, Feng Feng, Minyan Wang, Xingzhong Fang, Guofei Chen. (2022) Synthesis and characterization of poly(amide-imide)s with high Tg and low CTE derived from isomeric amide-containing diamines. EUROPEAN POLYMER JOURNAL, 179 (111558). [PMID:]
11. Shengdao Wang, Shuwen Zhang, Yanchao Yang, Zhongxin Dong, Guibin Wang. (2022) Direct electrochemical grafting of crystalline PAEK macromolecule on carbon fiber to enhance the interfacial properties of PEEK/CF composites. COMPOSITES SCIENCE AND TECHNOLOGY, 220 (109262). [PMID:]

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4-Nitrobenzoyl chloride - 98%, high purity , CAS No.122-04-3