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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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O648851-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $80.90 | |
O648851-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $168.90 | |
O648851-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $286.90 |
Flavonoids Chalcones Phenols Polyphenols
Synonyms | 20784-60-5|4'-O-Methylbroussochalcone B|(2e)-1-[2-Hydroxy-4-Methoxy-5-(3-Methylbut-2-En-1-Yl)phenyl]-3-(4-Hydroxyphenyl)prop-2-En-1-One|O-Methylbroussochalcone B|(E)-1-[2-hydroxy-4-methoxy-5-(3-methylbut-2-enyl)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one|2 |
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Specifications & Purity | ≥99% |
Biochemical and Physiological Mechanisms | 4'-O-Methylbavachalcone is a chalcone isolated from Psoralea corylifolia , inhibits severe acute respiratory syndrome coronavirus ( SARS-CoV ) papain-like protease ( PLpro ) activity, with an IC 50 of 10.1 μM. |
Storage Temp | Protected from light,Store at -80°C |
Shipped In | Ice chest + Ice pads |
Product Description | 4'-O-Methylbavachalcone is a chalcone isolated from Psoralea corylifolia , inhibits severe acute respiratory syndrome coronavirus ( SARS-CoV ) papain-like protease ( PLpro ) activity, with an IC 50 of 10.1 μM Form:Solid IC50& Target:IC50: 10.1 μM (PLpro) |
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IUPAC Name | (E)-1-[2-hydroxy-4-methoxy-5-(3-methylbut-2-enyl)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one |
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INCHI | InChI=1S/C21H22O4/c1-14(2)4-8-16-12-18(20(24)13-21(16)25-3)19(23)11-7-15-5-9-17(22)10-6-15/h4-7,9-13,22,24H,8H2,1-3H3/b11-7+ |
InChi Key | ZUGCRBMNFSAUOC-YRNVUSSQSA-N |
Canonical SMILES | CC(=CCC1=CC(=C(C=C1OC)O)C(=O)C=CC2=CC=C(C=C2)O)C |
Isomeric SMILES | CC(=CCC1=CC(=C(C=C1OC)O)C(=O)/C=C/C2=CC=C(C=C2)O)C |
Alternate CAS | 20784-60-5 |
PubChem CID | 5321765 |
MeSH Entry Terms | 4'-O-methylbroussochalcone B |
Molecular Weight | 338.4 |
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Solubility | DMSO : 50 mg/mL (147.75 mM; Need ultrasonic) |
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