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4-OMe-ARM1 , CAS No.O607195, Activator of Leukotriene A 4 hydrolase

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4-OMe-ARM1 , CAS No.O607195, Activator of Leukotriene A 4 hydrolase

Moligand™

PubChem CID: 145704648

Item Number

O607195

Grouped product items
SKU	Size	Availability	Price	Qty
O607195-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,190.90
O607195-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$3,334.90

View related series

Leukotriene A4 hydrolase Activator

Basic Description

Synonyms	compound 7
Specifications & Purity	Moligand™
Grade	Moligand™
Action Type	ACTIVATOR
Mechanism of action	Activator of Leukotriene A 4 hydrolase

Associated Targets(Human)

LTA4H Tchem Leukotriene A-4 hydrolase (1 Activities)

Discover Target: LTA4H

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

LTA4H Tchem Leukotriene A4 hydrolase (1442 Activities)

Discover Target: LTA4H

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	4-(4-{[4-(Methoxy)phenyl]methyl}phenyl)-1,3-thiazol-2-ylamine
INCHI	InChI=1S/C17H16N2OS/c1-20-15-8-4-13(5-9-15)10-12-2-6-14(7-3-12)16-11-21-17(18)19-16/h2-9,11H,10H2,1H3,(H2,18,19)
InChi Key	GGCCOFFVKJCRKJ-UHFFFAOYSA-N
Canonical SMILES	COc1ccc(cc1)Cc1ccc(cc1)c1csc(n1)N
Isomeric SMILES	COC1=CC=C(C=C1)CC2=CC=C(C=C2)C3=CSC(=N3)N
PubChem CID	145704648

Database links

RCSB PDB Ligand	LNJ
PubChem CID	145704648

Certificates

Certificate of Analysis(COA)

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References

1. Lee KH, Petruncio G, Shim A, Burdick M, Zhang Z, Shim YM, Noble SM, Paige M. (2019) Effect of Modifier Structure on the Activation of Leukotriene A₄ Hydrolase Aminopeptidase Activity.. J Med Chem, 62 (23): (10605-10616). [PMID:31751136] [10.1021/op500134e]

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