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5-[(3R,5S)-3-amino-5-(trifluoromethyl)piperidin-1-yl]quinoline-8-carbonitrile , Toll-like receptor 7 antagonist, CAS No.2101938-42-3, Toll-like receptor 7 antagonist

5-[(3R,5S)-3-amino-5-(trifluoromethyl)piperidin-1-yl]quinoline-8-carbonitrile , Toll-like receptor 7 antagonist, CAS No.2101938-42-3, Toll-like receptor 7 antagonist

Item Number

S609400

Grouped product items
SKU	Size	Availability	Price	Qty
S609400-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$316.90
S609400-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,165.90

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Basic Description

Synonyms	2101938-42-3 \| MS-24729 \| 8-Quinolinecarbonitrile, 5-((3R,5S)-3-amino-5-(trifluoromethyl)-1-piperidinyl)- \| Enpatoran [USAN] \| SCHEMBL18980030 \| EX-A5509 \| AKOS040759872 \| 5-[(3R,5S)-3-amino-5-(trifluoromethyl)piperidin-1-yl]quinoline-8-carbonitrile \| M50
Specifications & Purity	Moligand™
Grade	Moligand™
Action Type	ANTAGONIST
Mechanism of action	Toll-like receptor 7 antagonist

ALogP	2.7

TLR7 Tclin Toll-like receptor 7 (0 Activities)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

IUPAC Name	5-[(3R,5S)-3-amino-5-(trifluoromethyl)piperidin-1-yl]quinoline-8-carbonitrile
INCHI	InChI=1S/C16H15F3N4/c17-16(18,19)11-6-12(21)9-23(8-11)14-4-3-10(7-20)15-13(14)2-1-5-22-15/h1-5,11-12H,6,8-9,21H2/t11-,12+/m0/s1
InChi Key	BJXYHBKEQFQVES-NWDGAFQWSA-N
Canonical SMILES	C1C(CN(CC1N)C2=C3C=CC=NC3=C(C=C2)C#N)C(F)(F)F
Isomeric SMILES	C1[C@@H](CN(C[C@@H]1N)C2=C3C=CC=NC3=C(C=C2)C#N)C(F)(F)F
Alternate CAS	2101938-42-3
PubChem CID	129240620
Molecular Weight	320.31

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