5-(4-Phenoxybutoxy)psoralen - 98%, high purity , CAS No.870653-45-5, Channel blocker of K v1.3

Item Number

P120182

• Synonyms: 5-(4-Phenoxybutoxy)psoralen|870653-45-5|PAP-1|4-(4-phenoxybutoxy)-7H-furo[3,2-g]chromen-7-one|4-(4-phenoxybutoxy)furo[3,2-g]chromen-7-one|CHEMBL444449|7H-Furo[3,2-g][1]benzopyran-7-one, 4-(4-phenoxybutoxy)-|A62C114Q0Q|SPS-4251|7H-Furo(3,2-g)(1)benzopyran-
• Specifications & Purity: Moligand™, ≥98%
• Biochemical and Physiological Mechanisms: Selective inhibitor of Kv1.3, voltage-gated K+ channel. PAP-1 (EC50=2 nM) potently inhibits human T effector memory cell proliferation and delayed hypersensitivity. Effective orally or intraperitoneally. 5-(4-Phenoxybutoxy)psoralen has 23-fold selectivity
• Storage Temp: Store at 2-8°C,Protected from light
• Shipped In: Wet ice
• Grade: Moligand™
• Action Type: CHANNEL BLOCKER
• Mechanism of action: Channel blocker of K v1.3

Product Description

PAP-1 is selective inhibitor of Kv1.3, voltage-gated K+ channel. PAP-1 (EC50=2 nM) potently inhibits human T effector memory cell proliferation and delayed hypersensitivity. Effective orally or intraperitoneally. 5-(4-Phenoxybutoxy)psoralen has 23-fold selectivity for Kv1.3 over Kv1.5, and 33-125-fold selectivity over other Kv1 family channels. In treatment of multiple sclerosis