Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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E274770-20mg | 20mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $199.90 |
Arachidonic acid uptake inhibitor
Synonyms | Bio1_000150 | HMS3402I11 | Eicosatetraynoic acid | HMS1989I11 | HMS1361I11 | NCGC00021784-05 | MLS000069514 | NCGC00018135-04 | SCHEMBL68751 | UNII-5FEJ8J06DR | BSPBio_001449 | KBio3_000337 | MGLDCXPLYOWQRP-UHFFFAOYSA-N | Opera_ID_402 | cid_1780 | BDBM317 |
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Specifications & Purity | Moligand™, ≥98% |
Biochemical and Physiological Mechanisms | Arachidonic acid uptake inhibitor. Inhibits cyclooxygenase (ID 50 =8 µM) and lipoxygenases 5-, 12- and 15- (ID 50 =10, 0.3, and 0.2 µM respectively). Active in vivo and in vitro . |
Storage Temp | Store at 2-8°C |
Shipped In | Wet ice |
Grade | Moligand™ |
Action Type | AGONIST |
Mechanism of action | Agonist of Peroxisome proliferator-activated receptor-α |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Store at +4°C. The product can be stored for up to 12 months. |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | icosa-5,8,11,14-tetraynoic acid |
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INCHI | InChI=1S/C20H24O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h2-5,8,11,14,17-19H2,1H3,(H,21,22) |
InChi Key | MGLDCXPLYOWQRP-UHFFFAOYSA-N |
Canonical SMILES | CCCCCC#CCC#CCC#CCC#CCCCC(=O)O |
Isomeric SMILES | CCCCCC#CCC#CCC#CCC#CCCCC(=O)O |
PubChem CID | 1780 |
Molecular Weight | 296.5 |
PubChem CID | 1780 |
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ChEMBL Ligand | CHEMBL458328 |
BindingDB Ligand | 31752 |
CAS Registry No. | 1191-85-1 |
RCSB PDB Ligand | ITY |
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Solubility | Soluble in ethanol and DMSO |
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