Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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A337197-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $266.90 | |
A337197-500mg | 500mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $475.90 | |
A337197-1g | 1g | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $665.90 | |
A337197-5g | 5g | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,330.90 | |
A337197-10g | 10g | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,033.90 |
an acetazolamide intermediate
Synonyms | 5-Amino-1,3,4-thiadiazole-2-sulfonamide | 14949-00-9 | Tio-urasin | Zolamide | 1,3,4-Thiadiazole-2-sulfonamide, 5-amino- | CL 5343 | 5-Amino-TDSNH2 | 2-Amino-1,3,4-thiadiazole-5-sulfonamide | 2-Amino-1,3,4-thiadazole-5-sulfonamide | CHEMBL265674 | F687N81LIZ | MFCD03425417 | NSC |
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Storage Temp | Store at 2-8°C |
Shipped In | Wet ice |
Product Description | 5-Amino-1,3,4-thiadiazole-2-sulfonamide is an acetazolamide intermediate. |
pKa | pKa: 7.76 (Predicted) |
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Ki Data | CA VII: Ki= 5.2 nM (human); CA XII: Ki= 33 nM (human); CA IX: Ki= 41 nM (human); Carbonic anhydrase 15: Ki= 48 nM (mouse); CA II: Ki= 60 nM (human) |
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IUPAC Name | 5-amino-1,3,4-thiadiazole-2-sulfonamide |
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INCHI | InChI=1S/C2H4N4O2S2/c3-1-5-6-2(9-1)10(4,7)8/h(H2,3,5)(H2,4,7,8) |
InChi Key | VGMVBPQOACUDRU-UHFFFAOYSA-N |
Canonical SMILES | C1(=NN=C(S1)S(=O)(=O)N)N |
Isomeric SMILES | C1(=NN=C(S1)S(=O)(=O)N)N |
PubChem CID | 84724 |
Molecular Weight | 180.21 |
Enter Lot Number to search for COA:
Solubility | Soluble in DMSO, and methanol. |
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Refractive Index | n20D1.68 (Predicted) |
Boil Point(°C) | ~484.2° C at 760 mmHg (Predicted) |
Melt Point(°C) | 188-190° C (dec.) |
Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |