5′-Deoxy-5′-(methylthio)adenosine - 95%, high purity , CAS No.2457-80-9

  • ≥95%
Item Number
D168979
Grouped product items
SKUSizeAvailabilityPrice Qty
D168979-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$48.90
D168979-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$83.90
D168979-100mg
100mg
In stock
$147.90
D168979-250mg
250mg
In stock
$333.90
D168979-1g
1g
In stock
$1,198.90

Potent adenosine A 1 receptor agonist

Basic Description

SynonymsMethylthioadenosine | 2457-80-9 | 5'-methylthioadenosine | 5'-S-methyl-5'-thioadenosine | 5'-Deoxy-5'-(methylthio)adenosine | 5'-DEOXY-5'-METHYLTHIOADENOSINE | Vitamin L2 | 5-Methylthioadenosine | (2R,3R,4S,5S)-2-(6-Amino-9H-purin-9-yl)-5-((methylthio)methyl)tetrahydrofu
Specifications & Purity≥95%
Biochemical and Physiological MechanismsPotent A 1 receptor agonist (K i = 10 μM). Also an A 2 receptor antagonist and potent cAMP phosphodiesterase inhibitor (K i = 62 μM). Regulates gene expression, proliferation, differentiation and apoptosis. Anti-inflammatory agent. Orally active. Active i
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Associated Targets(Human)

COMT Tclin Catechol O-methyltransferase (404 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADORA1 Tclin Adenosine A1 receptor (17603 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADORA2A Tclin Adenosine A2a receptor (16305 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADORA2B Tclin Adenosine A2b receptor (7672 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADORA3 Tchem Adenosine A3 receptor (15931 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MTAP Tchem S-methyl-5-thioadenosine phosphorylase (233 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
INMT Tchem Indolethylamine N-methyltransferase (111 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FASN Tchem Fatty acid synthase (3390 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CCRF-CEM (65223 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MOLT-4 (49676 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADORA1 Tclin Adenosine receptor (26 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PRMT5 Tchem PRMT5/MEP50 complex (963 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Srm Spermidine synthase (60 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ahcy Adenosylhomocysteinase (45 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trypanosoma brucei brucei (13300 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
L1210 (27553 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
L5178Y (1809 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
mtaD 5-methylthioadenosine/S-adenosylhomocysteine deaminase (15 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Adora2b Adenosine A2 receptor (1828 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name (2R,3R,4S,5S)-2-(6-aminopurin-9-yl)-5-(methylsulfanylmethyl)oxolane-3,4-diol
INCHI InChI=1S/C11H15N5O3S/c1-20-2-5-7(17)8(18)11(19-5)16-4-15-6-9(12)13-3-14-10(6)16/h3-5,7-8,11,17-18H,2H2,1H3,(H2,12,13,14)/t5-,7-,8-,11-/m1/s1
InChi Key WUUGFSXJNOTRMR-IOSLPCCCSA-N
Canonical SMILES CSCC1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)O)O
Isomeric SMILES CSC[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)O
PubChem CID 439176
Molecular Weight 297.33

Certificates

Certificate of Analysis(COA)

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9 results found

Lot NumberCertificate TypeDateItem
K2117911Certificate of AnalysisSep 09, 2024 D168979
C2212544Certificate of AnalysisMay 10, 2022 D168979
A2416035Certificate of AnalysisMar 23, 2022 D168979
E2231162Certificate of AnalysisMar 23, 2022 D168979
E2231172Certificate of AnalysisMar 23, 2022 D168979
E2231173Certificate of AnalysisMar 23, 2022 D168979
E2231176Certificate of AnalysisMar 23, 2022 D168979
I2406168Certificate of AnalysisMar 23, 2022 D168979
B2307290Certificate of AnalysisJun 22, 2021 D168979

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H302:Harmful if swallowed

Precautionary Statements

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P270:Do not eat, drink or smoke when using this product.

P330:Rinse mouth.

P301+P317:IF SWALLOWED: Get medical help.

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