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5-Ethynyl-2'-deoxyuridine (EdU) , CAS No.61135-33-9
Metaboling Labeling reagents
Basic Description Synonyms 5-Ethynyl-2'-deoxyuridine|61135-33-9|2'-Deoxy-5-ethynyluridine|5-Ethynyl-2'-dU|Uridine, 2'-deoxy-5-ethynyl-|EdU (5-ethynyl-2'-deoxyuridine)|EdU (ethynyldeoxyuridine)|G373S00W2J|5-ethynyl-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimi Storage Temp Store at -20°C Shipped In Ice chest + Ice pads Product Description 5-Ethynyl-2_-deoxyuridine (EdU) is a thymidine analog that can be incorporated into replicating DNA for detection of cell proliferations. The alkyne handler can be used for subsequent ligation to azide-containing molecules through a highly efficient click chemistry reaction.
Names and Identifiers IUPAC Name 5-ethynyl-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione INCHI InChI=1S/C11H12N2O5/c1-2-6-4-13(11(17)12-10(6)16)9-3-7(15)8(5-14)18-9/h1,4,7-9,14-15H,3,5H2,(H,12,16,17)/t7-,8+,9+/m0/s1 InChi Key CDEURGJCGCHYFH-DJLDLDEBSA-N Canonical SMILES C#CC1=CN(C(=O)NC1=O)C2CC(C(O2)CO)O Isomeric SMILES C#CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)CO)O WGK Germany 3 PubChem CID 472172 Molecular Weight 252.22
Chemical and Physical Properties Specific Rotation[α] [α]D:23° (C=0.7,MeOH) Melt Point(°C) 199 °C
Safety and Hazards(GHS) Pictogram(s) GHS08 Signal Danger Hazard Statements H340: May cause genetic defects
H361: Suspected of damaging fertility or the unborn child
Precautionary Statements P280: Wear protective gloves/protective clothing/eye protection/face protection.
P405: Store locked up.
P501: Dispose of contents/container to ...
P281: Use personal protective equipment as required.
P203: Obtain, read and follow all safety instructions before use.
P318: if exposed or concerned, get medical advice.
WGK Germany 3
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