5-Ethynyluracil - 97%, high purity , Dihydropyrimidine dehydrogenase inhibitor, CAS No.59989-18-3, Dihydropyrimidine dehydrogenase inhibitor

  • ≥97%
Item Number
E404403
Grouped product items
SKUSizeAvailabilityPrice Qty
E404403-50mg
50mg
In stock
$23.90
E404403-250mg
250mg
In stock
$96.90

Basic Description

Synonyms2E2W0W5XIU | Y3G | 5-Ethynyl-2-hydroxypyrimidin-4(1H)-one | ADH-300004 | BDBM50124202 | 5-Ethynyl-6-hydroxypyrimidin-2(1H)-one | Compound 776C | FT-0667865 | 5-ETHYNYLURACIL | 5-ethynyl-uracil | 5-Ethynylpyrimidine-2,4-diol | ZB1821 | 5-ethynyl-1H-pyrimid
Specifications & Purity≥97%
Storage TempStore at 2-8°C,Protected from light,Argon charged
Shipped InWet ice
Action TypeINHIBITOR
Mechanism of actionDihydropyrimidine dehydrogenase inhibitor
Product Description

Maximum Absorption Wavelength:284(MeOH)nm

Product Properties

ALogP-0.7

Associated Targets(Human)

DPYD Tclin Dihydropyrimidine dehydrogenase [NADP(+)] (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
DPYD Tclin Dihydropyrimidine dehydrogenase (17 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 5-ethynyl-1H-pyrimidine-2,4-dione
INCHI InChI=1S/C6H4N2O2/c1-2-4-3-7-6(10)8-5(4)9/h1,3H,(H2,7,8,9,10)
InChi Key JOZGNYDSEBIJDH-UHFFFAOYSA-N
Canonical SMILES C#CC1=CNC(=O)NC1=O
Isomeric SMILES C#CC1=CNC(=O)NC1=O
PubChem CID 43157
Molecular Weight 136.11
Reaxy-Rn 638299

Certificates

Certificate of Analysis(COA)

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2 results found

Lot NumberCertificate TypeDateItem
B2302180Certificate of AnalysisSep 26, 2022 E404403
B2302181Certificate of AnalysisSep 26, 2022 E404403

Chemical and Physical Properties

SolubilityDMSO (Slightly), Methanol (Very Slightly, Heated)
SensitivityLight sensitive
Melt Point(°C)320 °C(dec.)

Safety and Hazards(GHS)

Reaxy-Rn 638299
Merck Index 3584

Related Documents

Solution Calculators