Grouped product items

SKU

Size

Availability

Price

Qty

F169520-100mg

100mg

Available within 4-8 weeks(?)

$48.90

F169520-250mg

250mg

Available within 4-8 weeks(?)

$110.90

Basic Description

Synonyms	1-.beta.-D-Arabinofuranosyl-5-fluoro-(1H,3H)-pyrimidine-2,4-dione \| 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-fluoro-pyrimidine-2,4-dione \| 2,4(1H,3H)-Pyrimidinedione, 1-.beta.-D-arabinofuranosyl-5-fluoro- \| 5UD \| BP-58617 \|
Specifications & Purity	Moligand™, ≥98%
Storage Temp	Store at 2-8°C,Argon charged
Shipped In	Wet ice
Grade	Moligand™
Note	250mg卖完停产，不再备货
Product Description	proapoptotic anitproliferative plant growth regulator

Associated Targets(Human)

HBB Tbio Hemoglobin beta chain (329 Activities)

Discover Target: HBB

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GLP1R Tclin Glucagon-like peptide 1 receptor (111429 Activities)

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TP53 Tchem Cellular tumor antigen p53 (48468 Activities)

Discover Target: TP53

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A498 (42825 Activities)

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ACHN (49357 Activities)

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CAKI-1 (44928 Activities)

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CCRF-CEM (65223 Activities)

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COLO 205 (50209 Activities)

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COLO 320DM (191 Activities)

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DLD-1 (17511 Activities)

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DMS-273 (14108 Activities)

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DU-145 (51482 Activities)

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HL-60 (67320 Activities)

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HT-1080 (3966 Activities)

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HT-29 (80576 Activities)

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IM-9 (160 Activities)

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K562 (73714 Activities)

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KM12 (47707 Activities)

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M14 (47487 Activities)

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MCF7 (126967 Activities)

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MKN-28 (466 Activities)

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MKN-45 (2102 Activities)

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MOLT-3 (638 Activities)

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MOLT-4 (49676 Activities)

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NUGC-3 (976 Activities)

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OVCAR-3 (48710 Activities)

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OVCAR-4 (44535 Activities)

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OVCAR-5 (45555 Activities)

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OVCAR-8 (47708 Activities)

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PANC-1 (6144 Activities)

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PC-3 (62116 Activities)

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PHA-Ly (22 Activities)

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Raji (5516 Activities)

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RPMI-8226 (44974 Activities)

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RXF 393 (41971 Activities)

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RXF 631 (11415 Activities)

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SF-295 (48000 Activities)

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SK-MEL-2 (46422 Activities)

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SK-MEL-28 (48833 Activities)

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SK-MEL-5 (47095 Activities)

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SK-OV-3 (52876 Activities)

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SN12C (47755 Activities)

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SNB-19 (46794 Activities)

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SNB-78 (14240 Activities)

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SW48 (312 Activities)

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T-24 (2342 Activities)

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TK-10 (45540 Activities)

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U-251 (51189 Activities)

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U-937 (7138 Activities)

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UACC-257 (46019 Activities)

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Associated Targets(non-human)

tmk Thymidylate kinase (360 Activities)

Discover Target: tmk

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Abcb1b P-glycoprotein 1 (174 Activities)

Discover Target: Abcb1b

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Human alphaherpesvirus 2 (4932 Activities)

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Human respirovirus 3 (1674 Activities)

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Mus musculus (284745 Activities)

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Vaccinia virus (4609 Activities)

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Human alphaherpesvirus 1 (11089 Activities)

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Sindbis virus (1599 Activities)

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Vesicular stomatitis virus (4460 Activities)

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Punta Toro virus (1491 Activities)

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Coxsackievirus B4 (2249 Activities)

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Respiratory syncytial virus (3434 Activities)

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CCRF S-180 (1031 Activities)

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FM3A (1296 Activities)

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L1210 (27553 Activities)

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Mammalian orthoreovirus 1 (1523 Activities)

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Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)

Discover Target: Nfe2l2

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HSP40, subfamily A, putative (505 Activities)

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vpr Aberrant vpr protein (14595 Activities)

Discover Target: vpr

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SKN7 Transcription factor SKN7 (365 Activities)

Discover Target: SKN7

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Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-fluoropyrimidine-2,4-dione
INCHI	InChI=1S/C9H11FN2O6/c10-3-1-12(9(17)11-7(3)16)8-6(15)5(14)4(2-13)18-8/h1,4-6,8,13-15H,2H2,(H,11,16,17)/t4-,5-,6-,8-/m1/s1
InChi Key	FHIDNBAQOFJWCA-UAKXSSHOSA-N
Canonical SMILES	C1=C(C(=O)NC(=O)N1C2C(C(C(O2)CO)O)O)F
Isomeric SMILES	C1=C(C(=O)NC(=O)N1[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)F
PubChem CID	9427
Molecular Weight	262.19

Database links

PubChem CID	9427
ChEBI	CHEBI:40154
CAS Registry No.	316-46-1
ChEMBL Ligand	CHEMBL54918
RCSB PDB Ligand	5UD

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number	Certificate Type	Date	Item
H1909229	Certificate of Analysis	Jun 17, 2022	F169520
B2224455	Certificate of Analysis	Jan 19, 2022	F169520
B2224481	Certificate of Analysis	Jan 19, 2022	F169520

Chemical and Physical Properties

Solubility	Soluble in Methanol (Slightly), Water (Slightly).
Specific Rotation[α]	18° (C=1,H2O)
Melt Point(°C)	185°C

Safety and Hazards(GHS)

Pictogram(s)	GHS08, GHS07
Signal	Warning
Hazard Statements	H341:Suspected of causing genetic defects H351:Suspected of causing cancer H302:Harmful if swallowed H312:Harmful in contact with skin H332:Harmful if inhaled
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P281:Use personal protective equipment as required. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P301+P317:IF SWALLOWED: Get medical help. P318:if exposed or concerned, get medical advice. P317:Get emergency medical help.

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5-Fluorouridine - 98%, high purity , CAS No.316-46-1

Basic Description

Associated Targets(Human)

Associated Targets(non-human)

Mechanisms of Action

Names and Identifiers

Database links

Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties

Safety and Hazards(GHS)

Related Documents

Solution Calculators

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

SKU	Size	Availability	Price	Qty
F169520-100mg	100mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$48.90
F169520-250mg	250mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$110.90