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G protein-coupled receptors (GPCRs)
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5-HEAT , CAS No.214416-49-6, Agonist of MT 1 receptor;Antagonist of MT 2 receptor

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5-HEAT , CAS No.214416-49-6, Agonist of MT 1 receptor;Antagonist of MT 2 receptor

Moligand™

CAS#: 214416-49-6
PubChem CID: 10849065

Item Number

H607220

Grouped product items
SKU	Size	Availability	Price	Qty
H607220-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$572.90
H607220-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,000.90

View related series

MT1 receptor Agonist MT2 receptor Antagonist

Basic Description

Synonyms	5-HEAT \| 214416-49-6 \| 5-hydroxyethoxy-N-acetyltryptamine \| N-[2-[5-(2-hydroxyethoxy)-1H-indol-3-yl]ethyl]acetamide \| CHEMBL126809 \| Acetamide, N-[2-[5-(2-hydroxyethoxy)-1H-indol-3-yl]ethyl]- \| n-{2-[5-(2-hydroxyethoxy)-1h-indol-3-yl]ethyl}acetamide \| GTPL1345 \| SCHEMBL6
Specifications & Purity	Moligand™
Grade	Moligand™
Action Type	AGONIST, ANTAGONIST
Mechanism of action	Agonist of MT 1 receptor;Antagonist of MT 2 receptor

Associated Targets(Human)

MTNR1A Tclin Melatonin receptor type 1A (2 Activities)

Discover Target: MTNR1A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MTNR1B Tclin Melatonin receptor type 1B (2 Activities)

Discover Target: MTNR1B

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MTNR1A Tclin Melatonin receptor 1A (2519 Activities)

Discover Target: MTNR1A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MTNR1A Tclin Melatonin receptor (989 Activities)

Discover Target: MTNR1A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Melatonin receptor 1B (19 Activities)

Discover Target:

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Melatonin receptor 1C (17 Activities)

Discover Target:

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	N-[2-[5-(2-hydroxyethoxy)-1H-indol-3-yl]ethyl]acetamide
INCHI	InChI=1S/C14H18N2O3/c1-10(18)15-5-4-11-9-16-14-3-2-12(8-13(11)14)19-7-6-17/h2-3,8-9,16-17H,4-7H2,1H3,(H,15,18)
InChi Key	CZPLTTWZQPLXMQ-UHFFFAOYSA-N
Canonical SMILES	OCCOc1ccc2c(c1)c(CCNC(=O)C)c[nH]2
Isomeric SMILES	CC(=O)NCCC1=CNC2=C1C=C(C=C2)OCCO
PubChem CID	10849065

Database links

PubChem CID	10849065
ChEMBL Ligand	CHEMBL126809
BindingDB Ligand	50066965
CAS Registry No.	214416-49-6
GPCRdb Ligand	5-HEAT

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5-HEAT , CAS No.214416-49-6, Agonist of MT 1 receptor;Antagonist of MT 2 receptor

Basic Description

Associated Targets(Human)

Associated Targets(non-human)

Names and Identifiers

Database links

Certificates

Certificate of Analysis(COA)

Related Documents

Solution Calculators

Molarity Calculator

Dilution Calculator

Reconstitution Calculator