5-Iodotubercidin - ≥98%, high purity , CAS No.24386-93-4

Item Number

L125077

• Synonyms: 5-Iodotubercidin | 24386-93-4 | 5-iodotubericidin | (2R,3R,4S,5R)-2-(4-AMINO-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-3,4-DIOL | NSC 113939 | 7-iodo-7-deazaadenosine | 7-iodotubercidin | 7-Deaza-7-iodoadenosine | CHEMBL99203 | CHEBI:40167 | (2
• Specifications & Purity: ≥98%
• Biochemical and Physiological Mechanisms: 5-Iodotubercidin (Itu) has been shown to inhibit mitogen-activated protein kinase (ERK2) (Ki = 525 nM), adenosine kinase (ADK) (Ki = 30 nM), casein kinases 1 & 2 (CSNK1A1 & CSNK2A1), protein kinase A (PKA) and insulin receptor kinase (IC50 ranging from 0.
• Storage Temp: Protected from light,Store at -20°C
• Shipped In: Ice chest + Ice pads
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

5-Iodotubercidin(NSC 113939; 5-ITu) is a potent adenosine kinase inhibitor (IC50 = 26 nM).
A potent and competitive inhibitor of ERK2, PKA, and ADK.