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- 5-Methylcytidine - 10mM in DMSO, high purity , CAS No.2140-61-6
5-Methylcytidine - 10mM in DMSO, high purity , CAS No.2140-61-6
Endogenous modified nucleoside. DNA methylation marker.
Basic Description
Synonyms | 5-Methylcytidine | 2140-61-6 | Cytidine, 5-methyl- | 5-methyl-cytidine | TL9PB228DC | CHEBI:20607 | 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidin-2-one | 4-amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2- |
Specifications & Purity | 10mM in DMSO |
Biochemical and Physiological Mechanisms | Endogenous modified nucleoside. DNA methylation marker. 5-methylcytosine derivative. 5-methyltransferase Trm4 substrate. Accumulates in uncharged histone tRNA molecules when 5-methyltransferase Trm4 is depleted. |
Storage Temp | Store at -80°C |
Shipped In | Ice chest + Ice pads |
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Associated Targets(non-human)
Mechanisms of Action
Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Names and Identifiers
IUPAC Name | 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidin-2-one |
INCHI | InChI=1S/C10H15N3O5/c1-4-2-13(10(17)12-8(4)11)9-7(16)6(15)5(3-14)18-9/h2,5-7,9,14-16H,3H2,1H3,(H2,11,12,17)/t5-,6-,7-,9-/m1/s1 |
InChi Key | ZAYHVCMSTBRABG-JXOAFFINSA-N |
Canonical SMILES | CC1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)O |
Isomeric SMILES | CC1=CN(C(=O)N=C1N)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O |
PubChem CID | 92918 |
Molecular Weight | 257.24 |
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Chemical and Physical Properties
Specific Rotation[α] | 15° (C=2,H2O) |
Melt Point(°C) | 211 °C(dec.) |
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