5-Methylcytidine - 10mM in DMSO, high purity , CAS No.2140-61-6

  • 10mM in DMSO
Item Number
M422586
Grouped product items
SKUSizeAvailabilityPrice Qty
M422586-1ml
1ml
Available within 4-8 weeks(?)
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$89.90

Endogenous modified nucleoside. DNA methylation marker.

Basic Description

Synonyms5-Methylcytidine | 2140-61-6 | Cytidine, 5-methyl- | 5-methyl-cytidine | TL9PB228DC | CHEBI:20607 | 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidin-2-one | 4-amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-
Specifications & Purity10mM in DMSO
Biochemical and Physiological MechanismsEndogenous modified nucleoside. DNA methylation marker. 5-methylcytosine derivative. 5-methyltransferase Trm4 substrate. Accumulates in uncharged histone tRNA molecules when 5-methyltransferase Trm4 is depleted.
Storage TempStore at -80°C
Shipped InIce chest + Ice pads

Associated Targets(non-human)

L1210 (27553 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
L1210/ara C (6 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Vero (26788 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidin-2-one
INCHI InChI=1S/C10H15N3O5/c1-4-2-13(10(17)12-8(4)11)9-7(16)6(15)5(3-14)18-9/h2,5-7,9,14-16H,3H2,1H3,(H2,11,12,17)/t5-,6-,7-,9-/m1/s1
InChi Key ZAYHVCMSTBRABG-JXOAFFINSA-N
Canonical SMILES CC1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)O
Isomeric SMILES CC1=CN(C(=O)N=C1N)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O
PubChem CID 92918
Molecular Weight 257.24

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

Specific Rotation[α]15° (C=2,H2O)
Melt Point(°C)211 °C(dec.)

Related Documents

Solution Calculators