Determine the necessary mass, volume, or concentration for preparing a solution.
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SKU | Size | Availability | Price | Qty |
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N341740-5mg | 5mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $48.90 | |
N341740-25mg | 25mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $220.90 | |
N341740-100mg | 100mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $793.90 |
an inhibitor of Na+/H+ antiport
Synonyms | 3-amino-5-(azepan-1-yl)-N-carbamimidoyl-6-chloropyrazine-2-carboxamide | NCGC00015108-06 | Spectrum2_001669 | Spectrum3_001662 | CHEBI:76400 | NCGC00015108-09 | NCGC00015108-03 | NCGC00093601-02 | SCHEMBL9852488 | 3-amino-5-(azepan-1-yl)-6-chloro-N-(diami |
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Specifications & Purity | Moligand™, ≥98% |
Storage Temp | Store at 2-8°C |
Shipped In | Wet ice |
Grade | Moligand™ |
Action Type | ALLOSTERIC MODULATOR |
Mechanism of action | Allosteric modulator of α 2A-adrenoceptor;Allosteric modulator of GnRH 1 receptor |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | 3-amino-5-(azepan-1-yl)-6-chloro-N-(diaminomethylidene)pyrazine-2-carboxamide |
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INCHI | InChI=1S/C12H18ClN7O/c13-8-10(20-5-3-1-2-4-6-20)18-9(14)7(17-8)11(21)19-12(15)16/h1-6H2,(H2,14,18)(H4,15,16,19,21) |
InChi Key | RQQJJXVETXFINY-UHFFFAOYSA-N |
Canonical SMILES | C1CCCN(CC1)C2=NC(=C(N=C2Cl)C(=O)N=C(N)N)N |
Isomeric SMILES | C1CCCN(CC1)C2=NC(=C(N=C2Cl)C(=O)N=C(N)N)N |
WGK Germany | 3 |
Alternate CAS | 1428-95-1 |
PubChem CID | 1794 |
MeSH Entry Terms | 3-amino-6-chloro-5-(1-homopiperidyl)-N-(diaminomethylene)pyrazinecarboxamide;5-(N,N-hexamethylene)amiloride;5-HMA;hexamethylene amiloride;hexamethyleneamiloride;HMA-5 |
Molecular Weight | 311.77 |
Enter Lot Number to search for COA:
Solubility | Soluble in 0.1N Hydrochloric Acid: 20 mg/ml |
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Pictogram(s) | GHS06 |
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Signal | Danger |
Hazard Statements | H301:Toxic if swallowed H311:Toxic in contact with skin H331:Toxic if inhaled |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P330:Rinse mouth. P361+P364:Take off immediately all contaminated clothing and wash it before reuse. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P316:Get emergency medical help immediately. |
WGK Germany | 3 |
RIDADR | UN28116.1/PGIII |
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1. Yang Gao, Kunming Li, Xiuyan Ren, Guanghui Gao. (2023) Thermochromic Hydrogels with Opaque-Transparent Gradient Transition for Switchable Window and Temperature Monitor. CHEMISTRY-A EUROPEAN JOURNAL, (e202302147). [PMID:37584162] [10.1002/chem.202302147] |
2. Xiuhua Sun, Shanshan Pan, Zhiren Guo, Yingxin Cui, Liang Ma, Xiaosong Yu, Taijiang Gui, Shougang Chen, Yan Liu, Changlu Gao. (2023) Synergy effect of bactericidal and antifouling with structure reversion and hydrolysis of cationic amphiphilic copolymer PHMA-b-PCBMAE to zwitterionic copolymer. PROGRESS IN ORGANIC COATINGS, 179 (107508). [PMID:] [10.1016/j.porgcoat.2023.107508] |
3. Liang YaoYao, Luo Juan, Yang Chenhao, Guo Shuning, Zhang Bowen, Chen Fengqianrui, Su Kairui, Zhang Yulong, Dong Yi, Wang Zhihao, Fu Hongda, Sui Guangchao, Wang Pengchao. (2022) Directed evolution of the PobR allosteric transcription factor to generate a biosensor for 4-hydroxymandelic acid. WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY, 38 (6): (1-10). [PMID:35501522] [10.1007/s11274-022-03286-5] |
4. Haiquan Zhang, Zijing Liu, Junping Mai, Ning Wang, Jie Zhong, Xianmin Mai, Nan Zhang. (2021) Super-elastic smart phase change material (SPCM) for thermal energy storage. CHEMICAL ENGINEERING JOURNAL, 411 (128482). [PMID:] [10.1016/j.cej.2021.128482] |
5. Kunming Li, Shengfei Meng, Shan Xia, Xiuyan Ren, Guanghui Gao. (2020) Durable and Controllable Smart Windows Based on Thermochromic Hydrogels. ACS Applied Materials & Interfaces, 12 (37): (42193–42201). [PMID:32820627] [10.1021/acsami.0c12710] |
6. Yaxin Hu, Xiaoqin Liang, Dongliang Wu, Bang Yu, Yijia Wang, Yifang Mi, Zhihai Cao, Zujin Zhao. (2020) Towards white-light emission of fluorescent polymeric nanoparticles with a single luminogen possessing AIE and TICT properties. Journal of Materials Chemistry C, 8 (2): (734-741). [PMID:] [10.1039/C9TC05690D] |
7. Li Liu, Guangchao Lv, Xiuyan Ren, Xinhe Li, Te Wang, Jingwen Dong, Zeyu Wang, Guangfeng Wu. (2019) Effect of size of latex particles on the mechanical properties of hydrogels reinforced by latex particles. RSC Advances, 9 (26): (14701-14707). [PMID:35516310] [10.1039/C9RA01688K] |
8. Zheng Li, Jianding Chen, Guijin Zou, Tongyuan Zhang, Dafu Wei, Xiang Xu, Yong Guan, Anna Zheng. (2019) Anionic living polymerization of alkyl methacrylate at ambient temperature and its mechanism research. JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY, 57 (10): (1130-1139). [PMID:] [10.1002/pola.29368] |
1. Yang Gao, Kunming Li, Xiuyan Ren, Guanghui Gao. (2023) Thermochromic Hydrogels with Opaque-Transparent Gradient Transition for Switchable Window and Temperature Monitor. CHEMISTRY-A EUROPEAN JOURNAL, (e202302147). [PMID:37584162] [10.1002/chem.202302147] |
2. Xiuhua Sun, Shanshan Pan, Zhiren Guo, Yingxin Cui, Liang Ma, Xiaosong Yu, Taijiang Gui, Shougang Chen, Yan Liu, Changlu Gao. (2023) Synergy effect of bactericidal and antifouling with structure reversion and hydrolysis of cationic amphiphilic copolymer PHMA-b-PCBMAE to zwitterionic copolymer. PROGRESS IN ORGANIC COATINGS, 179 (107508). [PMID:] [10.1016/j.porgcoat.2023.107508] |
3. Liang YaoYao, Luo Juan, Yang Chenhao, Guo Shuning, Zhang Bowen, Chen Fengqianrui, Su Kairui, Zhang Yulong, Dong Yi, Wang Zhihao, Fu Hongda, Sui Guangchao, Wang Pengchao. (2022) Directed evolution of the PobR allosteric transcription factor to generate a biosensor for 4-hydroxymandelic acid. WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY, 38 (6): (1-10). [PMID:35501522] [10.1007/s11274-022-03286-5] |
4. Haiquan Zhang, Zijing Liu, Junping Mai, Ning Wang, Jie Zhong, Xianmin Mai, Nan Zhang. (2021) Super-elastic smart phase change material (SPCM) for thermal energy storage. CHEMICAL ENGINEERING JOURNAL, 411 (128482). [PMID:] [10.1016/j.cej.2021.128482] |
5. Kunming Li, Shengfei Meng, Shan Xia, Xiuyan Ren, Guanghui Gao. (2020) Durable and Controllable Smart Windows Based on Thermochromic Hydrogels. ACS Applied Materials & Interfaces, 12 (37): (42193–42201). [PMID:32820627] [10.1021/acsami.0c12710] |
6. Yaxin Hu, Xiaoqin Liang, Dongliang Wu, Bang Yu, Yijia Wang, Yifang Mi, Zhihai Cao, Zujin Zhao. (2020) Towards white-light emission of fluorescent polymeric nanoparticles with a single luminogen possessing AIE and TICT properties. Journal of Materials Chemistry C, 8 (2): (734-741). [PMID:] [10.1039/C9TC05690D] |
7. Li Liu, Guangchao Lv, Xiuyan Ren, Xinhe Li, Te Wang, Jingwen Dong, Zeyu Wang, Guangfeng Wu. (2019) Effect of size of latex particles on the mechanical properties of hydrogels reinforced by latex particles. RSC Advances, 9 (26): (14701-14707). [PMID:35516310] [10.1039/C9RA01688K] |
8. Zheng Li, Jianding Chen, Guijin Zou, Tongyuan Zhang, Dafu Wei, Xiang Xu, Yong Guan, Anna Zheng. (2019) Anionic living polymerization of alkyl methacrylate at ambient temperature and its mechanism research. JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY, 57 (10): (1130-1139). [PMID:] [10.1002/pola.29368] |