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5-Nitro-α-oxo-N-(1R)-phenylethyl]-1H-indole-3-acetamide - >99%, high purity , CAS No.355022-97-8
Basic Description
Specifications & Purity | ≥99% |
Storage Temp | Room temperature |
Shipped In | Normal |
Product Description | TCS 1205 is reported to be a GABA|A|α1 partial agonist and GABA|A|α2 agonist|in vitro. |
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Product Properties
Ki Data | GABAA α2: Ki= 14 nM; GABAA α1: Ki= 121 nM |
Associated Targets(Human)
Associated Targets(non-human)
Names and Identifiers
IUPAC Name | 2-(5-nitro-1H-indol-3-yl)-2-oxo-N-[(1R)-1-phenylethyl]acetamide |
INCHI | InChI=1S/C18H15N3O4/c1-11(12-5-3-2-4-6-12)20-18(23)17(22)15-10-19-16-8-7-13(21(24)25)9-14(15)16/h2-11,19H,1H3,(H,20,23)/t11-/m1/s1 |
InChi Key | VCKKJKQZHHPPDR-LLVKDONJSA-N |
Canonical SMILES | CC(C1=CC=CC=C1)NC(=O)C(=O)C2=CNC3=C2C=C(C=C3)[N+](=O)[O-] |
Isomeric SMILES | C[C@H](C1=CC=CC=C1)NC(=O)C(=O)C2=CNC3=C2C=C(C=C3)[N+](=O)[O-] |
PubChem CID | 10315001 |
Molecular Weight | 337.33 |
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Chemical and Physical Properties
Solubility | Soluble in DMSO (100 mM). |
Specific Rotation[α] | α20D-45.7°, c = 1.2 in DMF |
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