Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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N136164-5g | 5g | In stock | $55.90 | |
N136164-25g | 25g | In stock | $150.90 | |
N136164-100g | 100g | In stock | $559.90 |
Histone deacetylase inhibitor
Synonyms | 5-Nitroso-8-hydroxyquinoline | 5-Nitrosoquinolin-8-ol | 3565-26-2 | 5-Nitroso-8-quinolinol | NSC 3852 | 8-QUINOLINOL, 5-NITROSO- | Hydron III | 5-Nitrosooxine | 5-Nitroso-8-cinnolinol | 8-Hydroxy-5-nitrosoquinoline | NSC3852 | NSC-3852 | RMH-79 | C9H6N2O2 | P302KW5VDN | MLS000775787 | S |
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Specifications & Purity | ≥95% |
Biochemical and Physiological Mechanisms | Histone deacetylase (HDAC) inhibitor. Causes cell differentiation and antiproliferative activity in MCF-7 human breast cancer cells in vitro and displays antitumor activity in vivo . |
Storage Temp | Store at -20°C,Argon charged |
Shipped In | Ice chest + Ice pads |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | 5-Nitroso-quinolin-8-ol is shown to have cell differentiation and antiproliferative activity in human breast cancer cells in tissue culture and antitumor activity in mice bearing P388 and L1210 leukemic cells. |
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IUPAC Name | 5-nitrosoquinolin-8-ol |
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INCHI | InChI=1S/C9H6N2O2/c12-8-4-3-7(11-13)6-2-1-5-10-9(6)8/h1-5,12H |
InChi Key | RZWRYPGAUIOOMK-UHFFFAOYSA-N |
Canonical SMILES | C1=CC2=C(C=CC(=C2N=C1)O)N=O |
Isomeric SMILES | C1=CC2=C(C=CC(=C2N=C1)O)N=O |
RTECS | VC8237000 |
PubChem CID | 19103 |
Molecular Weight | 174.16 |
Beilstein | 21(1)405 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
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H2217461 | Certificate of Analysis | Jun 19, 2024 | N136164 |
H2217462 | Certificate of Analysis | Jun 19, 2024 | N136164 |
K2021112 | Certificate of Analysis | Sep 14, 2022 | N136164 |
K2021111 | Certificate of Analysis | Sep 14, 2022 | N136164 |
Solubility | DMSO (Slightly), Methanol (Slightly) |
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Sensitivity | Light sensitive |
Pictogram(s) | GHS06, GHS07 |
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Signal | Danger |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H301:Toxic if swallowed |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
RTECS | VC8237000 |