Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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S609359-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $700.90 | |
S609359-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,000.90 |
Synonyms | 135415-73-5 | Mdo-cpt | 10,11-Methylenedioxy-20S-camptothecin | 10,11-Methylenedioxycamptothecin | 10,11-Methylenedioxy-20-camptothecin | FL118 | 104155-89-7 | CHEMBL307794 | NSC634724 | compound 5z [PMID: 8410981] | 10H-1,3-Dioxolo(4,5-g)pyrano(3,4:6,7)indolizino(1,2-b)quin |
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Specifications & Purity | Moligand™ |
Grade | Moligand™ |
Action Type | INHIBITOR |
Mechanism of action | Inhibitor of DNA topoisomerase I |
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INCHI | InChI=1S/C21H16N2O6/c1-2-21(26)13-5-15-18-11(7-23(15)19(24)12(13)8-27-20(21)25)3-10-4-16-17(29-9-28-16)6-14(10)22-18/h3-6,26H,2,7-9H2,1H3/t21-/m0/s1 |
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InChi Key | RPFYDENHBPRCTN-NRFANRHFSA-N |
Canonical SMILES | CC[C@@]1(O)C(=O)OCc2c1cc1c3nc4cc5OCOc5cc4cc3Cn1c2=O |
Isomeric SMILES | CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=C6C(=CC5=C4)OCO6)O |
PubChem CID | 72403 |
PubChem CID | 72403 |
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ChEMBL Ligand | CHEMBL307794 |
CAS Registry No. | 104155-89-7 |
BindingDB Ligand | 50036133 |
Enter Lot Number to search for COA:
1. Wall ME, Wani MC, Nicholas AW, Manikumar G, Tele C, Moore L, Truesdale A, Leitner P, Besterman JM. (1993) Plant antitumor agents. 30. Synthesis and structure activity of novel camptothecin analogs.. J Med Chem, 36 (18): (2689-700). [PMID:8410981] |