6-HydroxyMelatonin - 95%, high purity , CAS No.2208-41-5, Agonist of MT 1 receptor;Agonist of MT 2 receptor

Item Number
H133184
Grouped product items
SKUSizeAvailabilityPrice Qty
H133184-1mg
1mg
In stock
$257.90
H133184-5mg
5mg
In stock
$892.90
H133184-10mg
10mg
In stock
$1,249.90
H133184-25mg
25mg
In stock
$2,187.90
H133184-50mg
50mg
In stock
$3,062.90
H133184-100mg
100mg
In stock
$4,288.90
H133184-250mg
250mg
In stock
$6,866.90

Basic Description

SynonymsFT-0669728 | LP00612 | MLS000860057 | UNII-TV437T5077 | 6-hydroxy melatonin | NCGC00015495-06 | 5-22-12-00353 (Beilstein Handbook Reference) | SR-01000075901-1 | CHEBI:2198 | AS-78853 | Melatonin,6-Hydroxy | NCGC00015495-04 | C05643 | CCG-204701 | HMS2231
Specifications & PurityMoligand™, ≥95%
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeAGONIST
Mechanism of actionAgonist of MT 1 receptor;Agonist of MT 2 receptor

Associated Targets(Human)

MTNR1A Tclin Melatonin receptor type 1A (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
MTNR1B Tclin Melatonin receptor type 1B (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ARSA Tbio Cerebroside-sulfatase (655 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALOX15B Tchem Arachidonate 15-lipoxygenase, type II (7244 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MTNR1A Tclin Melatonin receptor 1A (2519 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2D6 Tclin Cytochrome P450 2D6 (33882 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP1A2 Tchem Cytochrome P450 1A2 (26471 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2C9 Tchem Cytochrome P450 2C9 (32119 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2C19 Tchem Cytochrome P450 2C19 (29246 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FEN1 Tchem Flap endonuclease 1 (12055 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UGT2B7 Tchem UDP-glucuronosyltransferase 2B7 (787 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HSD17B10 Tchem Endoplasmic reticulum-associated amyloid beta-peptide-binding protein (20669 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM4E Tchem Lysine-specific demethylase 4D-like (40243 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HPGD Tchem 15-hydroxyprostaglandin dehydrogenase [NAD+] (24926 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GMNN Tbio Geminin (128009 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ATAD5 Tbio ATPase family AAA domain-containing protein 5 (122566 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MPHOSPH8 Tbio M-phase phosphoprotein 8 (656 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UGT1A7 Tbio UDP-glucuronosyltransferase 1-7 (106 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UGT1A10 Tbio UDP-glucuronosyltransferase 1-10 (257 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RGS4 Tchem Regulator of G-protein signaling 4 (13867 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MTNR1A Tclin Melatonin receptor (989 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GLS Tchem Glutaminase kidney isoform, mitochondrial (16997 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RACGAP1 Tbio Rac GTPase-activating protein 1 (2057 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Melatonin receptor 1B (19 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Npsr1 Neuropeptide S receptor (260 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
fba Putative fructose-1,6-bisphosphate aldolase (15559 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FTL Ferritin light chain (43324 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name N-[2-(6-hydroxy-5-methoxy-1H-indol-3-yl)ethyl]acetamide
INCHI InChI=1S/C13H16N2O3/c1-8(16)14-4-3-9-7-15-11-6-12(17)13(18-2)5-10(9)11/h5-7,15,17H,3-4H2,1-2H3,(H,14,16)
InChi Key OMYMRCXOJJZYKE-UHFFFAOYSA-N
Canonical SMILES CC(=O)NCCC1=CNC2=CC(=C(C=C21)OC)O
Isomeric SMILES CC(=O)NCCC1=CNC2=CC(=C(C=C21)OC)O
WGK Germany 3
RTECS AC3607000
PubChem CID 1864
Molecular Weight 248.28

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

9 results found

Lot NumberCertificate TypeDateItem
C2202223Certificate of AnalysisMar 11, 2022 H133184
D1912157Certificate of AnalysisFeb 22, 2022 H133184
E2227011Certificate of AnalysisFeb 09, 2022 H133184
E2227021Certificate of AnalysisFeb 09, 2022 H133184
E2227028Certificate of AnalysisFeb 09, 2022 H133184
E2227035Certificate of AnalysisFeb 09, 2022 H133184
E2227037Certificate of AnalysisFeb 09, 2022 H133184
E2227045Certificate of AnalysisFeb 09, 2022 H133184
E2227046Certificate of AnalysisFeb 09, 2022 H133184

Safety and Hazards(GHS)

Pictogram(s) GHS08,   GHS07
Signal Warning
Hazard Statements

H351:Suspected of causing cancer

H302:Harmful if swallowed

Precautionary Statements

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P270:Do not eat, drink or smoke when using this product.

P330:Rinse mouth.

P203:Obtain, read and follow all safety instructions before use.

P301+P317:IF SWALLOWED: Get medical help.

P318:if exposed or concerned, get medical advice.

WGK Germany 3
RTECS AC3607000

Related Documents

Citations of This Product

1. Yu Meng Wang,Wei Yi Wang,Li Yan Sun,Qiang Li,Zhi Jun Zhao,Jian Hu,Rong Yu Zhang,Li Hua Wang.  (2020-11-25)  Serum Metabolomic Indicates Potential Biomarkers and Metabolic Pathways of Pediatric Kashin-Beck Disease..  Biomedical and environmental sciences : BES,  33  ((10)): (750-759).  [PMID:33228834]

References

1. Yu Meng Wang,Wei Yi Wang,Li Yan Sun,Qiang Li,Zhi Jun Zhao,Jian Hu,Rong Yu Zhang,Li Hua Wang.  (2020-11-25)  Serum Metabolomic Indicates Potential Biomarkers and Metabolic Pathways of Pediatric Kashin-Beck Disease..  Biomedical and environmental sciences : BES,  33  ((10)): (750-759).  [PMID:33228834]

Solution Calculators