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6-Mercaptopurine-riboside-5'-triphosphate (aqueous solution) - ≥95%, high purity , CAS No.27652-34-2

  • ≥95%
Item Number
M276546
Grouped product items
SKUSizeAvailabilityPrice Qty
M276546-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$419.90

Competitive T4 RNA ligase inhibitor

View related series
DNA/RNA Synthesis

Basic Description

Synonyms6-Thioinosine-5'-triphosphate | BDBM50594498 | 9H-Purine-6(1H)-thione, 9-beta-D-ribofuranosyl-, 5'-tetrahydrogen triphosphate | 6-thioinosine triphosphate | Inosine 5'-(tetrahydrogen triphosphate), 6-thio- | NSC 169530 | 9-beta-D-Ribofuranosyl-9H-purine-6
Specifications & Purity≥95%
Biochemical and Physiological MechanismsATP analog. Competitive inhibitor of the T4 RNA ligase adenylation reaction.
Storage TempStore at -20°C,Desiccated
Shipped InIce chest + Ice pads
NoteProviding storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Application:

Competitive inhibitor of T4 RNA ligase;
Kinetic parameters with thiopurine methyltransferase;
Interaction with (sodium-potassium ion)-dependent ATPase

Associated Targets

CGAS Tchem Cyclic GMP-AMP synthase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

P2RX3 Tclin P2X purinoceptor 3 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

P2RX4 Tchem P2X purinoceptor 4 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

P2RX7 Tchem P2X purinoceptor 7 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

P2RX2 Tchem P2X purinoceptor 2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

P2RX1 Tchem P2X purinoceptor 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name [[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-sulfanylidene-3H-purin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
INCHI InChI=1S/C10H15N4O13P3S/c15-6-4(1-24-29(20,21)27-30(22,23)26-28(17,18)19)25-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)31/h2-4,6-7,10,15-16H,1H2,(H,20,21)(H,22,23)(H,11,12,31)(H2,17,18,19)/t4-,6-,7-,10-/m1/s1
InChi Key GQNRDWAOABGWGP-KQYNXXCUSA-N
Canonical SMILES C1=NC(=S)C2=C(N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O
Isomeric SMILES C1=NC(=S)C2=C(N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O
PubChem CID 3036942
Molecular Weight 524.22 (free acid)

Certificates

Certificate of Analysis(COA)

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2 results found

Lot NumberCertificate TypeDateItem
G2415432Certificate of AnalysisMar 29, 2024 M276546
G2415433Certificate of AnalysisMar 29, 2024 M276546

Chemical and Physical Properties

SolubilitySupplied in water (10 mM)

Related Documents

Solution Calculators