6-Thioguanine - 98%, high purity , DNA inhibitor, CAS No.154-42-7, DNA inhibitor

Item Number

T106639

• Synonyms: Tioguanin | Tioguanina [INN-Spanish] | THG | WIX31ZPX66 | 2-Amino 6MP | SMR000857244 | Thioguanine2-Amino-6-purinethiol | Tioguaninum [INN-Latin] | DX4 | MLS001333131 | 2-Amino-1,7-dihydro-6H-purin-6-thion | 2-Amino-1,7-dihydro-6H-purin-6-thion [Czech] |
• Specifications & Purity: Moligand™, ≥98%
• Biochemical and Physiological Mechanisms: Antimetabolite used in the treatment of leukemias. Competes with hypoxanthine and guanine for the enzyme hypoxanthine-guanine phosphoribosyltransferase, which catalzyes a critical step in the generation of purine nucleotides. Ribosylated and phosphorylate
• Shipped In: Normal
• Grade: Moligand™
• Action Type: INHIBITOR
• Mechanism of action: DNA inhibitor
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

6-Thioguanine is a chemotherapy drug that demonstrates immunosuppressive, anti-neoplastic, and anti-cancer activities. This chemical is often used to treat leukemia and inflammatory diseases. Chemical produces dose-dependent inhibition of stimulated expression of TRAIL protein.
An immunosuppressive, anti-neoplastic, and anti-cancer